Search Results - "Kozik, Zuza"
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Clustering of Tir during enteropathogenic E. coli infection triggers calcium influx-dependent pyroptosis in intestinal epithelial cells
Published in PLoS biology (30-12-2020)“…Clustering of the enteropathogenic Escherichia coli (EPEC) type III secretion system (T3SS) effector translocated intimin receptor (Tir) by intimin leads to…”
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Insights from multi-omic modeling of neurodegeneration in xeroderma pigmentosum using an induced pluripotent stem cell system
Published in Cell reports (Cambridge) (25-06-2024)“…Xeroderma pigmentosum (XP) is caused by defective nucleotide excision repair of DNA damage. This results in hypersensitivity to ultraviolet light and increased…”
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Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7
Published in Molecular oncology (01-02-2024)“…The F‐box and WD repeat domain containing 7 (FBXW7) tumour suppressor gene encodes a substrate‐recognition subunit of Skp, cullin, F‐box (SCF)‐containing…”
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Impaired neutrophil migration underpins host susceptibility to infectious colitis
Published in Mucosal immunology (01-10-2024)“…[Display omitted] Citrobacter rodentium models infection with enteropathogenic Escherichia coli and ulcerative colitis (UC). While C57BL/6 (C57) mice recover,…”
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Abstract PO1-13-04: Distinct immune signatures discriminate between patients defined as exceptional survivors of metastatic breast cancer compared to those with rapidly progressing treatment resistant breast cancers
Published in Cancer research (Chicago, Ill.) (02-05-2024)“…Background: "Atypical responders" can encompass three sub- categories of patients: "exceptional responders" (those with an unusually favourable treatment…”
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