Search Results - "Kozawa, Junji"

Renal function is associated with blood neurofilament light chain level in older adults by Akamine, Shoshin, Marutani, Noriko, Kanayama, Daisuke, Gotoh, Shiho, Maruyama, Riki, Yanagida, Kanta, Sakagami, Yukako, Mori, Kohji, Adachi, Hiroyoshi, Kozawa, Junji, Maeda, Norikazu, Otsuki, Michio, Matsuoka, Takaaki, Iwahashi, Hiromi, Shimomura, Iichiro, Ikeda, Manabu, Kudo, Takashi

“…Neurofilament light chain (NfL) is a novel biomarker of neurodegenerative diseases. It is detectable in the peripheral blood, allowing low-invasive assessment…”
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Increased NKX6.1 expression and decreased ARX expression in alpha cells accompany reduced beta-cell volume in human subjects by Fujita, Yukari, Kozawa, Junji, Fukui, Kenji, Iwahashi, Hiromi, Eguchi, Hidetoshi, Shimomura, Iichiro

“…Pancreatic islet cells have plasticity, such as the abilities to dedifferentiate and transdifferentiate. Islet cell conversion to other characteristic cell is…”
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Ectopic Fat Accumulation in Pancreas and Heart by Kozawa, Junji, Shimomura, Iichiro

“…Ectopic fat is found in liver, muscle, and kidney and is known to accumulate as visceral fat. In recent years, ectopic fat has also been observed in the…”
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Human adipose-derived mesenchymal stem cells prevent type 1 diabetes induced by immune checkpoint blockade by Kawada-Horitani, Emi, Kita, Shunbun, Okita, Tomonori, Nakamura, Yuto, Nishida, Hiroyuki, Honma, Yoichi, Fukuda, Shiro, Tsugawa-Shimizu, Yuri, Kozawa, Junji, Sakaue, Takaaki, Kawachi, Yusuke, Fujishima, Yuya, Nishizawa, Hitoshi, Azuma, Miyuki, Maeda, Norikazu, Shimomura, Iichiro

“…Aims/hypothesis Immunomodulators blocking cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death protein 1 (PD-1) or programmed…”
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A Histological Study of Fulminant Type 1 Diabetes Mellitus Related to Human Cytomegalovirus Reactivation by Yoneda, Sho, Imagawa, Akihisa, Fukui, Kenji, Uno, Sae, Kozawa, Junji, Sakai, Makoto, Yumioka, Toshiki, Iwahashi, Hiromi, Shimomura, Iichiro

“…Abstract Context: Fulminant type 1 diabetes mellitus (T1DM) is thought to be partly caused by virus infection. Objective: This study investigated the mechanism…”
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Characteristics and clinical course of type 1 diabetes mellitus related to anti-programmed cell death-1 therapy by Baden, Megu Yamaguchi, Imagawa, Akihisa, Abiru, Norio, Awata, Takuya, Ikegami, Hiroshi, Uchigata, Yasuko, Oikawa, Yoichi, Osawa, Haruhiko, Kajio, Hiroshi, Kawasaki, Eiji, Kawabata, Yumiko, Kozawa, Junji, Shimada, Akira, Takahashi, Kazuma, Tanaka, Shoichiro, Chujo, Daisuke, Fukui, Tomoyasu, Miura, Junnosuke, Yasuda, Kazuki, Yasuda, Hisafumi, Kobayashi, Tetsuro, Hanafusa, Toshiaki

“…Aims We conducted a national survey to clarify the characteristics and clinical course of type 1 diabetes related to anti-programmed cell death-1 therapy…”
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Preoperative hemoglobin A1c is associated with postoperative bleeding after vitrectomy for vitreous hemorrhage in patients with diabetic retinopathy by Motoda, Saori, Kanai, Masanori, Sakimoto, Susumu, Ozawa, Harutoshi, Ishibashi, Chisaki, Fujita, Shingo, Hosokawa, Yoshiya, Baden, Megu Y., Fujita, Yukari, Kimura, Takekazu, Tokunaga, Ayumi, Nammo, Takao, Fukui, Kenji, Kozawa, Junji, Sakaguchi, Hirokazu, Nishida, Kohji, Shimomura, Iichiro

“…We previously reported that a high HbA1c level 3 months before vitrectomy for vitreous hemorrhage or a large preoperative decrease in the HbA1c level over 3…”
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Daily Glucose Profiles after Switching from Injectable to Oral Semaglutide in Patients with Type 2 Diabetes Mellitus by Takahara, Mitsuyoshi, Shiraiwa, Toshihiko, Katakami, Naoto, Maeno, Yoshifumi, Yamamoto, Kaoru, Shiraiwa, Yuka, Yoshida, Yoko, Kozawa, Junji, Shimomura, Iichiro

“…Objective This prospective observational study explored the changes in the daily glycemic profile after switching from injectable to oral semaglutide in…”
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Genetic assessment using whole-exome sequencing for a young hypertriglyceridemic patient with repeated acute pancreatitis by Fujita, Shingo, Nishizawa, Hitoshi, Miyashita, Yohei, Imada, Tasuku, Yamaguchi, Takashi, Murano, Takeyoshi, Bujo, Hideaki, Asano, Yoshihiro, Kozawa, Junji, Maeda, Norikazu, Shimomura, Iichiro

“…Hypertriglyceridemia is caused not only by environmental factors but also by genetic factors. Severe hypertriglyceridemia is prone to complications of acute…”
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Pancreatic fat is related to the longitudinal decrease in the increment of C‐peptide in glucagon stimulation test in type 2 diabetes patients by Ishibashi, Chisaki, Kozawa, Junji, Hosakawa, Yoshiya, Yoneda, Sho, Kimura, Takekazu, Fujita, Yukari, Fukui, Kenji, Iwahashi, Hiromi, Shimomura, Iichiro

“…Aims/Introduction The relationship between pancreatic fatty infiltration and diabetes is widely known, whereas the causal relationship is not clear…”
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Effect of urinary glucose concentration and pH on signal intensity in magnetic resonance images by Yoshimura, Sho, Tanaka, Hisashi, Kawabata, Shuichi, Kozawa, Junji, Takahashi, Hiroto, Hidaka, Yoh, Hotta, Masaki, Kashiwagi, Nobuo, Tomiyama, Noriyuki

“…Purpose With advances in anti-diabetes drugs, increasing numbers of patients have high urinary glucose concentrations, which may alter magnetic resonance (MR)…”
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Association of crossing capillaries in the finger nailfold with diabetic retinopathy in type 2 diabetes mellitus by Shikama, Maiko, Sonoda, Nao, Morimoto, Akiko, Suga, Sayaka, Tajima, Tetsuya, Kozawa, Junji, Maeda, Norikazu, Otsuki, Michio, Matsuoka, Taka‐Aki, Shimomura, Iichiro, Ohno, Yuko

“…Aims/Introduction Crossing capillaries in the finger nailfold might potentially be a novel diabetic retinopathy (DR) biomarker that could be assessed…”
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Bivalent GAD autoantibody ELISA improves clinical utility and risk prediction for adult autoimmune diabetes by Kawasaki, Eiji, Shimada, Akira, Imagawa, Akihisa, Abiru, Norio, Awata, Takuya, Oikawa, Yoichi, Osawa, Haruhiko, Kawabata, Yumiko, Kozawa, Junji, Kobayashi, Tetsuro, Takahashi, Kazuma, Chujo, Daisuke, Fukui, Tomoyasu, Miura, Junnosuke, Yasuda, Kazuki, Yasuda, Hisafumi, Kajio, Hiroshi, Hanafusa, Toshiaki, Ikegami, Hiroshi

“…Aim/Introduction To investigate the differences in the clinical significance and glutamic acid decarboxylase autoantibody (GADA) affinity between RIA…”
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New diagnostic criteria (2023) for slowly progressive type 1 diabetes (SPIDDM): Report from Committee on Type 1 Diabetes in Japan Diabetes Society (English version) by Shimada, Akira, Kawasaki, Eiji, Abiru, Norio, Awata, Takuya, Oikawa, Yoichi, Osawa, Haruhiko, Kajio, Hiroshi, Kozawa, Junji, Takahashi, Kazuma, Chujo, Daisuke, Noso, Shinsuke, Fukui, Tomoyasu, Miura, Junnosuke, Yasuda, Kazuki, Yasuda, Hisafumi, Imagawa, Akihisa, Ikegami, Hiroshi

“…The diagnostic criteria for slowly progressive type 1 diabetes (slowly progressive insulin-dependent diabetes mellitus; SPIDDM) have been revised by the…”
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Islet inflammation is associated with pancreatic fatty infiltration and hyperglycemia in type 2 diabetes by Horii, Tomomi, Fujita, Yukari, Ishibashi, Chisaki, Fukui, Kenji, Eguchi, Hidetoshi, Kozawa, Junji, Shimomura, Iichiro

“…IntroductionChronic inflammation is observed in type 2 diabetes islets, and fat deposition in the pancreas affects insulin secretion and glucose tolerance…”
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A Japanese patient with a 2p25.3 terminal deletion presented with early‐onset obesity, intellectual disability and diabetes mellitus: A case report by Sakaue, Taka‐aki, Obata, Yoshinari, Fujishima, Yuya, Kozawa, Junji, Otsuki, Michio, Yamamoto, Toshiyuki, Maeda, Norikazu, Nishizawa, Hitoshi, Shimomura, Iichiro

“…ABSTRACT 2p25.3 deletion syndrome is a rare genetic disorder that accompanies various phenotypic features, including early‐onset obesity and intellectual…”
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Homeostasis model assessment of insulin resistance for evaluating insulin sensitivity in patients with type 2 diabetes on insulin therapy by Okita, Kohei, Iwahashi, Hiromi, Kozawa, Junji, Okauchi, Yukiyoshi, Funahashi, Tohru, Imagawa, Akihisa, Shimomura, Iichiro

“…Homeostasis model assessment of insulin resistance (HOMA-IR) is a simple and useful method for evaluating insulin sensitivity. But it is difficult to apply to…”
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Lipid droplet accumulation in β cells in patients with type 2 diabetes is associated with insulin resistance, hyperglycemia and β cell dysfunction involving decreased insulin granules by Horii, Tomomi, Kozawa, Junji, Fujita, Yukari, Kawata, Satoshi, Ozawa, Harutoshi, Ishibashi, Chisaki, Yoneda, Sho, Nammo, Takao, Miyagawa, Jun-ichiro, Eguchi, Hidetoshi, Shimomura, Iichiro

“…Background and objective Pancreatic fat is a form of ectopic fat. Lipid droplets (LDs) are also observed in β cells; however, the pathophysiological…”
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Comparing the clinical significance and antigen specificity of insulinoma‐associated antigen‐2 autoantibodies between radioimmunoassay and enzyme‐linked immunosorbent assay in Japanese patients with type 1 diabetes by Kawasaki, Eiji, Shimada, Akira, Imagawa, Akihisa, Abiru, Norio, Awata, Takuya, Oikawa, Yoichi, Osawa, Haruhiko, Kawabata, Yumiko, Kozawa, Junji, Kobayashi, Tetsuro, Takahashi, Kazuma, Chujo, Daisuke, Fukui, Tomoyasu, Miura, Junnosuke, Yasuda, Kazuki, Yasuda, Hisafumi, Kajio, Hiroshi, Hanafusa, Toshiaki, Ikegami, Hiroshi

“…Aims/Introduction This study aimed to investigate the clinical significance and antigen specificity of autoantibodies to insulinoma‐associated antigen‐2…”
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Immune checkpoint inhibitor-related type 1 diabetes mellitus which develops long after treatment discontinuation: a case report and review of literature by Obata, Yoshinari, Takemoto, Miho, Sakaue, Taka-aki, Kawata, Satoshi, Mukai, Kosuke, Miyashita, Kazuyuki, Kozawa, Junji, Nishizawa, Hitoshi, Shimomura, Iichiro

“…Immune checkpoint inhibitor (ICI)-related type 1 diabetes is an immune-related adverse event (irAE), occurring in slightly less than 1% of patients undergoing…”
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