Search Results - "Kozan, Darby"

Is It Ever Wise to Edit Wild-Type Alleles? Engineered CRISPR Alleles Versus Millions of Years of Human Evolution by Kozan, Darby W, Farber, Steven A

“…The tremendous burden of lipid metabolism diseases, coupled with recent developments in human somatic gene editing, has motivated researchers to propose…”
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From worms to humans: Understanding intestinal lipid metabolism via model organisms by Kozan, Darby W., Derrick, Joshua T., Ludington, William B., Farber, Steven A.

“…The intestine is responsible for efficient absorption and packaging of dietary lipids before they enter the circulatory system. This review provides a…”
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A high-cholesterol zebrafish diet promotes hypercholesterolemia and fasting-associated liver steatosis by Jin, Yang, Kozan, Darby, Young, Eric D., Hensley, Monica R., Shen, Meng-Chieh, Wen, Jia, Moll, Tabea, Anderson, Jennifer L., Kozan, Hannah, Rawls, John F., Farber, Steven A.

“…Zebrafish are an ideal model organism to study lipid metabolism and to elucidate the molecular underpinnings of human lipid-associated disorders. Unlike murine…”
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Comparing the utility of in vivo transposon mutagenesis approaches in yeast species to infer gene essentiality by Levitan, Anton, Gale, Andrew N., Dallon, Emma K., Kozan, Darby W., Cunningham, Kyle W., Sharan, Roded, Berman, Judith

“…In vivo transposon mutagenesis, coupled with deep sequencing, enables large-scale genome-wide mutant screens for genes essential in different growth…”
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