Search Results - "Koyama, Hironari"

Sedative and physiological effects of alfaxalone intramuscular administration in cynomolgus monkeys (Macaca fascicularis) by WADA, Sou, KOYAMA, Hironari, YAMASHITA, Kazuto

“…To evaluate the sedative and physiological effects of alfaxalone intramuscular (IM) administration, 12 healthy cynomolgus monkeys were administered single IM…”
Get full text

Effect of road transportation on the serum biochemical parameters of cynomolgus monkeys and beagle dogs by OCHI, Takehiro, YAMADA, Azusa, NAGANUMA, Yuki, NISHINA, Noriko, KOYAMA, Hironari

“…To determine the effect of long-distance (approximately 600 km) road transportation on the blood biochemistry of laboratory animals, we investigated the…”
Get full text

Effects of housing conditions on behaviors and biochemical parameters in juvenile cynomolgus monkeys (Macaca fascicularis) by Koyama, Hironari, Tachibana, Yuki, Takaura, Kaoru, Takemoto, Shigetoshi, Morii, Kiyoshi, Wada, Sou, Kaneko, Hayato, Kimura, Mayuko, Toyoda, Atsushi

“…To investigate the effects of environmental enrichment on laboratory monkeys, we studied behavioral and physiological differences following changes in housing…”
Get full text

Disruption of zinc homeostasis and the pathogenesis of senile dementia by Kawahara, Masahiro, Mizuno, Dai, Koyama, Hironari, Konoha, Keiko, Ohkawara, Susumu, Sadakane, Yutaka

“…Zinc (Zn) is an essential trace element that is abundantly present in the brain. Although Zn plays crucial roles in learning and memory, numerous studies have…”
Get full text

Protective activity of carnosine and anserine against zinc-induced neurotoxicity: a possible treatment for vascular dementia by Mizuno, Dai, Konoha-Mizuno, Keiko, Mori, Miwako, Sadakane, Yutaka, Koyama, Hironari, Ohkawara, Susumu, Kawahara, Masahiro

“…Carnosine (β-alanyl- l -histidine) is a small dipeptide with numerous beneficial effects, including the maintenance of the acid-base balance, antioxidant…”
Get full text

d-Histidine and l-histidine attenuate zinc-induced neuronal death in GT1-7 cells by Kawahara, Masahiro, Sadakane, Yutaka, Koyama, Hironari, Konoha, Keiko, Ohkawara, Susumu

“…Although zinc (Zn) is an essential trace element, excess Zn causes neuronal death following transient global ischemia and plays a central role in the…”
Get full text

Involvement of trace elements in the pathogenesis of prion diseases by Mizuno, Dai, Koyama, Hironari, Ohkawara, Susumu, Sadakane, Yutaka, Kawahara, Masahiro

“…Prion diseases are progressive neurodegenerative diseases that are associated with conformational changes that convert normal cellular prion protein (PrP(C))…”
Get more information

Anesthetic Effect of a Combination of Medetomidine-Midazolam-Butorphanol in Cynomolgus Monkeys (Macaca fascicularis) by OCHI, Takehiro, NISHIURA, Ippei, TATSUMI, Mitsuyoshi, HIRANO, Yoshimi, YAHAGI, Kouichi, SAKURAI, Yasuhiro, MATSUYAMA-FUJIWARA, Kanako, SUDO, Yuji, NISHINA, Noriko, KOYAMA, Hironari

“…The anesthetic effect of a combination of medetomidine, midazolam and butorphanol (Me-Mi-Bu) was evaluated in healthy cynomolgus monkeys. The Me-Mi-Bu…”
Get full text

Stimulation of butyrate production by gluconic acid in batch culture of pig cecal digesta and identification of butyrate-producing bacteria by Tsukahara, Takamitsu, Koyama, Hironari, Okada, Masaaki, Ushida, Kazunari

“…Gluconic acid reaches the large intestine to stimulate lactic acid bacteria. However, the fermentation pattern of gluconic acid has yet to be elucidated…”
Get more information

Quantitative and antioxidative behavior of Trolox in rats' blood and brain by HPLC-UV and SMFIA-CL methods by Wada, Mitsuhiro, Wada, Misato, Ikeda, Rie, Fuchigami, Yuki, Koyama, Hironari, Ohkawara, Susumu, Kawakami, Shigeru, Kuroda, Naotaka, Nakashima, Kenichiro

“…Trolox, a water‐soluble vitamin E analogue has been used as a positive control in Trolox equivalent antioxidant capacity and oxygen radical antioxidant…”
Get full text

Effect of new training technique on affinity of cynomolgus monkeys for animal care personnel by Nishimoto, Ai, Tachibana, Yuki, Takaura, Kaoru, Ochi, Takehiro, Koyama, Hironari

“…To confirm our hypothesis that the sex and age of cynomolgus monkeys influences the effect of training, we employed a new training technique designed to…”
Get full text

Dietary sodium gluconate protects rats from large bowel cancer by stimulating butyrate production by Kameue, Chiyoko, Tsukahara, Takamitsu, Yamada, Kouji, Koyama, Hironari, Iwasaki, Yoshie, Nakayama, Keizo, Ushida, Kazunari

“…Butyrate has an antitumorigenic effect on colorectal cancer cell lines. Dietary sodium gluconate (GNA) promotes butyrate production in the large intestine…”
Get more information

Stimulation of butyrate production through the metabolic interaction among lactic acid bacteria, Lactobacillus acidophilus, and lactic acid-utilizing bacteria, Megasphaera elsdenii, in porcine cecal digesta by Tsukahara, T.(Kyoto Prefectural Univ. (Japan)), Hashizume, K, Koyama, H, Ushida, K

“…In this study, we examined the potential of Megasphaera elsdenii as a probiotic agent in combination with sodium gluconate. We also examined the combination of…”
Get full text

Effects of Transport Stress on Serum Alkaline Phosphatase Activity in Beagle Dogs by Ochi, Takehiro, Nishiura, Ippei, Tatsumi, Mitsuyoshi, Hirano, Yoshimi, Yahagi, Kouichi, Sakurai, Yasuhiro, Sudo, Yuji, Koyama, Hironari, Hagita, Yuichi, Fujimoto, Yoshikatsu, Kitamura, Shinji, Hashimoto, Hideki, Nakamura, Tomoya, Yamada, Asobi, Tanimoto, Masayoshi, Nishina, Noriko

“…Here, to determine the effects of transport stress on blood parameters in dogs, we investigated the changes in hematologic and serum chemical parameters in…”
Get full text

Sedative and physiological effects of alfaxalone intramuscular administration in cynomolgus monkeys (Macaca fascicularis) by WADA, Sou, KOYAMA, Hironari, YAMASHITA, Kazuto

“…To evaluate the sedative and physiological effects of alfaxalone intramuscular (IM) administration, 12 healthy cynomolgus monkeys were administered single IM…”
Get full text

Impacts of dosing and drug withdrawal period on tacrolimus-based triple therapy in a non-human primate renal transplantation model by Naganuma, Yuuki, Maeda, Masashi, Nakamura, Koji, Fukahori, Hidehiko, Satake, Hiroyuki, Murakami, Ryuji, Hanaoka, Kaori, Higashi, Yasuyuki, Koyama, Hironari, Morokata, Tatsuaki

“…Non-human primate (NHP) renal transplantation models are widely used vivo models for researching new immunosuppressive therapies including allograft tolerance…”
Get full text

Zinc, copper, and carnosine attenuate neurotoxicity of prion fragment PrP106-126 by Kawahara, Masahiro, Koyama, Hironari, Nagata, Tetsuya, Sadakane, Yutaka

“…Prion diseases are progressive neurodegenerative diseases that are associated with the conversion of normal cellular prion protein (PrP(C)) to abnormal…”
Get full text

An In Vitro System Comprising Immortalized Hypothalamic Neuronal Cells (GT1–7 Cells) for Evaluation of the Neuroendocrine Effects of Essential Oils by Kawahara, Masahiro, Haneda, Toshihiro, Yamazaki, Kentaro, Mori, Miwako, Konoha-Mizuno, Keiko, Mizuno, Dai, Koyama, Hironari

“…Aromatherapy and plant-based essential oils are widely used as complementary and alternative therapies for symptoms including anxiety. Furthermore, it was…”
Get full text

Effects of housing conditions on behaviors and biochemical parameters in juvenile cynomolgus monkeys (Macaca fascicularis) by KOYAMA, Hironari, TACHIBANA, Yuki, TAKAURA, Kaoru, TAKEMOTO, Shigetoshi, MORII, Kiyoshi, WADA, Sou, KANEKO, Hayato, KIMURA, Mayuko, TOYODA, Atsushi

“…To investigate the effects of environmental enrichment on laboratory monkeys, we studied behavioral and physiological differences following changes in housing…”
Get full text

Megasphaera elsdenii JCM1772T normalizes hyperlactate production in the large intestine of fructooligosaccharide-fed rats by stimulating butyrate production by Hashizume, Kenta, Tsukahara, Takamitsu, Yamada, Kouji, Koyama, Hironari, Ushida, Kazunari

“…Hyperlactate production is related to disorders of the large intestine such as inflammatory bowel diseases. Lactate, an intermediate in hindgut fermentation,…”
Get more information