Search Results - "Koy, C"

Proteoform profiling of peripheral blood serum proteins from pregnant women provides a molecular IUGR signature by Wölter, M., Röwer, C., Koy, C., Rath, W., Pecks, U., Glocker, M.O.

“…Intrauterine growth restriction (IUGR) is an important cause of perinatal morbidity and mortality and contributes substantially to medically indicated preterm…”
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Facile Fabrication and Instant Application of Miniaturized Antibody-Decorated Affinity Columns for Higher-Order Structure and Functional Characterization of TRIM21 Epitope Peptides by Al-Majdoub, M, Opuni, K. F. M, Koy, C, Glocker, M. O

“…Both epitope excision and epitope extraction methods, combined with mass spectrometry, generate precise informations on binding surfaces of full-length…”
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Mass spectrometric and peptide chip characterization of an assembled epitope: analysis of a polyclonal antibody model serum directed against the Sjøgren/systemic lupus erythematosus autoantigen TRIM21 by Al-Majdoub, M., Koy, C., Lorenz, P., Thiesen, H.-J., Glocker, M. O.

“…We demonstrate the development of a mass spectrometry‐based epitope‐mapping procedure in combination with Western blot analysis that works also with antigens…”
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Differentiation of HELLP patients from healthy pregnant women by proteome analysis—On the way towards a clinical marker set by Heitner, J.C., Koy, C., Kreutzer, M., Gerber, B., Reimer, T., Glocker, M.O.

“…As the pathogenesis of the HELLP-syndrome is unknown, a complex consideration regarding the changes in the plasma as the main transport medium in the body is…”
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Tissue transglutaminase (TG2) facilitates phosphatidylserine exposure and calpain activity in calcium-induced death of erythrocytes by Sarang, Z, Mádi, A, Koy, C, Varga, S, Glocker, M O, Ucker, D S, Kuchay, S, Chishti, A H, Melino, G, Fésüs, L, Szondy, Z

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Mass Spectrometric and Peptide Chip Epitope Mapping of Rheumatoid Arthritis Autoantigen RA33 by El-Kased, R.F., Koy, C., Deierling, T., Lorenz, P., Qian, Z., Li, Y., Thiesen, H.-J., Glocker, M.O.

“…The protein termed RA33 was determined to be one major autoantigen in rheumatoid arthritis (RA) patients and antiRA33 auto antibodies were found to appear…”
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OS079. Fetal deglycosylated apolipoprotein C-III (Apo C-III0) concentration is altered in intrauterine growth restriction by Pecks, U, Wölter, M, Röwer, C, Koy, C, Reimer, T, Rath, W, Glocker, M.O

“…Introduction We recently demonstrated that serum lipid levels are altered in growth restricted fetuses (IUGR) [1]. Objectives We now aimed to analyse the…”
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Mass Spectrometric and Peptide Chip Epitope Analysis on the RA33 Autoantigen with Sera from Rheumatoid Arthritis Patients by El-Kased, R.F., Koy, C., Lorenz, P., Drynda, S., Guthke, R., Qian, Z., Koczan, D., Li, Y., Kekow, J., Thiesen, H.-J., Glocker, M.O.

“…As the potential of epitope chips for routine application in diagnostics relies on the careful selection of peptides, reliable epitope mapping results are of…”
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High Detection Sensitivity Achieved with Cryogenic Detectors in Combination with Matrix-Assisted Laser Desorption/Ionisation Time-of-Flight Mass Spectrometry by Christ, P., Rutzinger, S., Seidel, W., Uchaikin, S., Pröbst, F., Koy, C., Glocker, M.O.

“…Cryogenic detectors directly measure the impact energy of any impinging particle independent of its velocity. Thus, a very high, mass-independent, detection…”
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A proteome signature for intrauterine growth restriction derived from multifactorial analysis of mass spectrometry-based cord blood serum profiling by Wölter, Manja, Röwer, Claudia, Koy, Cornelia, Reimer, Toralf, Rath, Werner, Pecks, Ulrich, Glocker, Michael O.

“…Intrauterine growth restriction (IUGR) is defined as a condition in which the fetus does not reach its genetically given growth potential, resulting in low…”
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Mass spectrometric and peptide chip characterization of an assembled epitope: analysis of a polyclonal antibody model serum directed against the Sjoegren/systemic lupus erythematosus autoantigen TRIM21 by Al-Majdoub, M, Koy, C, Lorenz, P, Thiesen, H-J, Glocker, MO

“…We demonstrate the development of a mass spectrometry-based epitope-mapping procedure in combination with Western blot analysis that works also with antigens…”
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Mass spectrometric protein structure characterization reveals cause of migration differences of haptoglobin a chains in two-dimensional gel electrophoresis by MIKKAT, Stefan, KOY, Cornelia, ULBRICH, Markus, RINGEL, Bruno, GLOCKER, Michael O

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Matrix-assisted laser desorption/ionization- quadrupole ion trap-time of flight mass spectrometry sequencing resolves structures of unidentified peptides obtained by in-gel tryptic digestion of haptoglobin derivatives from human plasma proteomes by Koy, Cornelia, Mikkat, Stefan, Raptakis, Emmanuel, Sutton, Chris, Resch, Martin, Tanaka, Koichi, Glocker, Michael O.

“…Two‐dimensional gel electrophoresis‐separated and excised haptoglobin α2‐chain protein spots were subjected to in‐gel digestion with trypsin. Previously…”
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ApoCIII Spezies im mütterlichen Serum bei IUGR – Potential zur Diagnose durch MALDI ToF MS? by Pecks, U, Wölter, M, Röwer, C, Koy, C, Maass, N, Glocker, M, Rath, W

“…Fragestellung: Kürzlich konnten wir in einer Fall-Kontrollstudie darstellen, dass sich ApoCIII Spezies im Nabelschnurblut zur Unterscheidung zwischen IUGR und…”
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MS characterization of apheresis samples from rheumatoid arthritis patients for the improvement of immunoadsorption therapy – a pilot study by Kienbaum, Mike, Koy, Cornelia, Montgomery, Helen V., Drynda, Susanne, Lorenz, Peter, Illges, Harald, Tanaka, Koichi, Kekow, Joern, Guthke, Reinhard, Thiesen, Hans‐Juergen, Glocker, Michael O.

“…Identification of proteins from apheresis samples was performed by both SDS‐PAGE and 2‐D gel separation of eluted proteins from staphylococcal protein A‐based…”
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Cryodetector mass spectrometry profiling of plasma samples for HELLP diagnosis: An exploratory study by Koy, Cornelia, Heitner, Juliane C., Woisch, Ralf, Kreutzer, Michael, Serrano-Fernandez, Pablo, Gohlke, Rüdiger, Reimer, Toralf, Glocker, Michael O.

“…The cryodetector MS‐based screening method enables the rapid and reliable separation of hemolysis, elevated liver enzymes, and low platelets syndrome (HELLP)…”
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Catalytic asymmetric hydrosilylation of butadiynes: A new synthesis of optically active allenes by Tillack, Annegret, Michalik, Dirk, Koy, Cornelia, Michalik, Manfred

“…The Rh-catalyzed hydrosilylation of butadiynes to chiral allenes in the presence of chiral phosphine ligands is described. For the first time an enantiomeric…”
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A new asymmetric synthesis of optically active allenes via metal catalyzed hydrosilylation by Tillack, Annegret, Koy, Cornelia, Michalik, Dirk, Fischer, Christine

“…The Rh and Ni catalyzed hydrosilylation of butadiynes to chiral allenes in the presence of chiral phosphine ligands is described. For the first time an…”
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Primary Structure Details of Haptoglobin α Chain Proteins from Human Plasma Samples are Resolved by Matrix-Assisted Laser Desorption/Ionization Quadrupole Ion Trap Time-of-Flight Multiple-Stage Tandem Mass Spectrometry Sequencing by Koy, Cornelia, Resch, Martin, Tanaka, Koichi, Glocker, Michael O.

“…Matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight multiple-stage tandem mass spectrometry analyses lead to the rapid…”
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SYNTHESIS OF NEW ALKYL DERIVATIVES OF 2,2′-DIHYDROXY-1,1′-BINAPHTHYL by Koy, Cornelia, Michalik, Manfred, Oehme, Günther, Fischer, Christine, Tillack, Annegret, Baudisch, Hannelore, Kempe, Rhett

“…2′-Hydroxy-1,1′-binaphthyl-2-yl phosphate 4 reacts with various alkylating agents under controlled conditions to give differently alkylated phosphoric esters…”
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