Search Results - "Kowalski, D L"

Proarrhythmic Safety of Repeat Doses of Mirabegron in Healthy Subjects: A Randomized, Double-Blind, Placebo-, and Active-Controlled Thorough QT Study by Malik, M, van Gelderen, E M, Lee, J H, Kowalski, D L, Yen, M, Goldwater, R, Mujais, S K, Schaddelee, M P, de Koning, P, Kaibara, A, Moy, S S, Keirns, J J

“…Potential effects of the selective β3‐adrenoceptor agonist mirabegron on cardiac repolarization were studied in healthy subjects. The four‐arm, parallel,…”
Get full text

Vaginal evisceration : Presentation and management in postmenopausal women by KOWALSKI, L. D, SESKI, J. C, TIMMINS, P. F, KANBOUR, A. I, KUNSCHNER, A. J, KANBOUR-SHAKIR, A

“…Vaginal evisceration is a rare event, often associated with previous vaginal surgery in postmenopausal women. To date, 57 cases have been described in the…”
Get full text

Inhaled misoprostol blocks guinea pig antigen-induced bronchoconstriction and airway inflammation by Smith, W G, Thompson, J M, Kowalski, D L, McKearn, J P

“…Inhaled E-type prostaglandins (PGE) have been shown to modulate responses to both allergic and nonallergic provocation. Misoprostol, a PGE1 analog, was…”
Get more information

Polymer delivery of the active isomer of misoprostol: a solution to the intestinal side effect problem by Perkins, W E, Bianchi, R G, Tremont, S J, Collins, P W, Casler, J J, Fenton, R L, Wagner, G M, McGrath, M P, Stolzenbach, J C, Kowalski, D L

“…SC-53450 is a new polybutadiene-based polymer system with an acid labile diisopropyl silyl ether linker to which the active isomer of misoprostol (SC-30249) is…”
Get more information

A case‐matched molecular comparison of extraovarian versus primary ovarian adenocarcinoma by Kowalski, Lynn D., Kanbour, Anisa I., Price, Fredric V., Finkelstein, Sydney D., Christopherson, Wayne A., Seski, Jan C., Naus, Gregory J., Burnham, Judith A., Kanbour‐Shakir, Amal, Edwards, Robert P.

“…BACKGROUND Extraovarian müllerian adenocarcinoma (EOM) resembles primary ovarian carcinoma (POC) both histologically and clinically, yet little is known…”
Get full text

Evaluation of a Region on Chromosome 1p in Ovarian Serous Carcinoma That Is Frequently Deleted in Uterine Papillary Serous Carcinoma by Herzog, Thomas J., Kowalski, Lynn D., Liu, Hua, Arlt, Martin, Swisher, Elizabeth

“…Objective. The goal of this study was to assess the involvement of chromosome 1p deletion in ovarian papillary serous carcinoma (OPSC) via high-resolution…”
Get full text

Analysis of MSH3 in endometrial cancers with defective DNA mismatch repair by Swisher, E M, Mutch, D G, Herzog, T J, Rader, J S, Kowalski, L D, Elbendary, A, Goodfellow, P J

“…To clarify the origin of defective mismatch repair (MMR) in sporadic endometrial cancers with microsatellite instability (MSI), a thorough mutation analysis…”
Get more information

Mutational analysis of MLH1 and MSH2 in 25 prospectively-acquired RER+ endometrial cancers by Kowalski, Lynn D., Mutch, David G., Herzog, Thomas J., Rader, Janet S., Goodfellow, Paul J.

“…Mutations in the DNA mismatch repair (MMR) genes MLH1 and MSH2 have been linked to several human cancers which display the replication error (RER) phenotype…”
Get full text

Inflammatory endotypes of chronic rhinosinusitis based on cluster analysis of biomarkers by Tomassen, Peter, MD, Vandeplas, Griet, MD, Van Zele, Thibaut, MD, PhD, Cardell, Lars-Olaf, MD, PhD, Arebro, Julia, MD, Olze, Heidi, MD, PhD, Förster-Ruhrmann, Ulrike, MD, Kowalski, Marek L., MD, PhD, Olszewska-Ziąber, Agnieszka, MD, Holtappels, Gabriele, De Ruyck, Natalie, Wang, Xiangdong, MD, PhD, Van Drunen, Cornelis, PhD, Mullol, Joaquim, MD, PhD, Hellings, Peter, MD, PhD, Hox, Valerie, MD, PhD, Toskala, Elina, MD, PhD, Scadding, Glenis, MD, Lund, Valerie, MD, Zhang, Luo, MD, PhD, Fokkens, Wytske, MD, PhD, Bachert, Claus, MD, PhD

“…Background Current phenotyping of chronic rhinosinusitis (CRS) into chronic rhinosinusitis with nasal polyps (CRSwNP) and chronic rhinosinusitis without nasal…”
Get full text

Anaphylaxis in children and adolescents: The European Anaphylaxis Registry by Grabenhenrich, Linus B., MD, MPH, Dölle, Sabine, PhD, Moneret-Vautrin, Anne, MD, Köhli, Alice, MD, Lange, Lars, MD, Spindler, Thomas, MD, Ruëff, Franziska, MD, Nemat, Katja, MD, Maris, Ioana, MD, Roumpedaki, Eirini, MD, Scherer, Kathrin, MD, Ott, Hagen, MD, Reese, Thomas, MD, Mustakov, Tihomir, MD, Lang, Roland, PhD, Fernandez-Rivas, Montserrat, MD, Kowalski, Marek L., MD, PhD, Bilò, Maria B., MD, Hourihane, Jonathan O'B., MD, Papadopoulos, Nikolaos G., MD, Beyer, Kirsten, MD, Muraro, Antonella, MD, Worm, Margitta, MD

“…Background Anaphylaxis in children and adolescents is a potentially life-threatening condition. Its heterogeneous clinical presentation and sudden occurrence…”
Get full text

Approaches to the diagnosis and management of patients with a history of nonsteroidal anti-inflammatory drug–related urticaria and angioedema by Kowalski, Marek L., MD, PhD, Woessner, Katharine, MD, PhD, Sanak, Marek, MD, PhD

“…Nonsteroidal anti-inflammatory drug (NSAID)–induced urticarial and angioedema reactions are among the most commonly encountered drug hypersensitivity reactions…”
Get full text

Nursing care of the patient with acute renal failure by Johnson, H K, Kowalski, L D, Brungardt, C J, Cotton, K E

Get more information

Overt and Occult Hypoxemia in Patients Hospitalized With COVID-19 by Gadrey, Shrirang M, Mohanty, Piyus, Haughey, Sean P, Jacobsen, Beck A, Dubester, Kira J, Webb, Katherine M, Kowalski, Rebecca L, Dreicer, Jessica J, Andris, Robert T, Clark, Matthew T, Moore, Christopher C, Holder, Andre, Kamaleswaran, Rishi, Ratcliffe, Sarah J, Moorman, J Randall

“…Progressive hypoxemia is the predominant mode of deterioration in COVID-19. Among hypoxemia measures, the ratio of the Pao to the Fio (P/F ratio) has optimal…”
Get full text

Cutaneous Manifestation of Drug Allergy and Hypersensitivity by Zalewska-Janowska, Anna, MD, PhD, Spiewak, Radoslaw, MD, PhD, Kowalski, Marek L., MD, PhD

“…Drug hypersensitivity reactions may manifest with either organ-specific or systemic symptoms, but cutaneous eruptions are the most common manifestations…”
Get full text

Prostaglandin E2 and lipoxin A4 in PBMCs are associated with immune tolerance during venom immunotherapy by Lech, Zuzanna, PhD, Chalubinski, Maciej, MD, PhD, Kosiński, Slawomir, MD, PhD, Smorawska, Ewa, MD, PhD, Bassin, Claudio, Sci Tec, Akdis, Cezmi A., MD, PhD, Grzegorczyk, Janina, PhD, Kowalski, Marek L., MD, PhD

“…Successful venom immunotherapy (VIT) is associated with generation of IL-10-producing regulatory T and B cells, which induce tolerance to the relevant allergen…”
Get full text

Clinical Trials of Aspirin Treatment After Desensitization in Aspirin-Exacerbated Respiratory Disease by Kowalski, Marek L., MD, PhD, Wardzyńska, Aleksandra, MD, PhD, Makowska, Joanna S., MD, PhD

“…The clinical efficacy of aspirin treatment after desensitization in patients with respiratory disease exacerbated by nonsteroidal anti-inflammatory drugs has…”
Get full text

Rhinovirus-Induced Immune Response in Nasal Epithelial Cells by Kowalski, Marek L., MD, PhD, Olszewska-Ziober, Agnieszka, Pawelczyk, Malgorzata, Piechota-Polanczyk, Aleksandra, Moskwa, Sylwia, Jarzebska, Marzanna, Jablonska, Agnieszka, Globinska, Anna

“…Rationale We aimed to compare immune response to rhinovirus (RV) infection and TLR stimulation in human nasal epithelial cells (HNECs) from patients with…”
Get full text

Classification of Reactions to Nonsteroidal Antiinflammatory Drugs by Kowalski, Marek L., MD, PhD, Stevenson, Donald D., MD

“…Hypersensitivity reactions to NSAIDs may occur in susceptible individuals and vary in symptom (skin, respiratory tract, and solid organs), severity (from mild…”
Get full text

Health-related quality of life in food-allergic adults from eight European countries by Goossens, Nicole J., MD, Flokstra-de Blok, Bertine M.J., PhD, van der Meulen, Gerbrich N., MD, Arnlind, Marianne H., MPH, PhD, Asero, Ricardo, MD, Barreales, Laura, MD, Burney, Peter, MD, Cerecedo, Imnaculada, MD, PhD, Clausen, Michael, MD, Fernandéz-Rivas, Monteserrat, MD, PhD, Frewer, Lynn, PhD, de la Hoz Caballer, Belén, MD, PhD, Jansson, Sven-Arne, PhD, Jedrzejczak-Czechowicz, Monica, MD, PhD, Knulst, André C., MD, PhD, Kowalski, Marek L., MD, PhD, Papadopoulos, Nikos G., MD, PhD, Purohit, Ashok, MD, Rokicka, Ewa, PhD, Starosta, Pawel, PhD, Vásquez-Cortés, Sonia, MD, Duiverman, Eric J., MD, PhD, Dubois, Anthony E.J., MD, PhD

“…Abstract Background Food allergy can impair health-related quality of life (HRQL). Food Allergy Quality of Life Questionnaires (FAQLQs) have been developed and…”
Get full text

Validation of the GA2 LEN chamber for trials in allergy: Innovation of a mobile allergen exposure chamber by Zuberbier, Torsten, MD, Abelson, Mark B., MD, Akdis, Cezmi A., MD, Bachert, Claus, MD, PhD, Berger, Uwe, Bindslev-Jensen, Carsten, MD, Boelke, Georg, Bousquet, Jean, MD, Canonica, Giorgio Walter, MD, Casale, Thomas B., MD, Jutel, Marek, Kowalski, Marek L., MD, Madonini, Enzo, MD, Papadopoulos, Nikolaos G., MD, Pfaar, Oliver, Sehlinger, Torsten, Bergmann, Karl-Christian, MD

“…Abstract Background Field clinical trials of pollen allergy are impacted by the impossibility to predict and to determine individual allergen exposure, due to…”
Get full text