Search Results - "Kowalewski, J"

HLA ligandome analysis identifies the underlying specificities of spontaneous antileukemia immune responses in chronic lymphocytic leukemia (CLL) by Kowalewski, Daniel J., Schuster, Heiko, Backert, Linus, Berlin, Claudia, Kahn, Stefan, Kanz, Lothar, Salih, Helmut R., Rammensee, Hans-Georg, Stevanovic, Stefan, Stickel, Juliane Sarah

“…Significance Effective cancer immunotherapy relies on specific immune recognition of tumor-associated and tumor-specific antigens. In chronic lymphocytic…”
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The immunopeptidomic landscape of ovarian carcinomas by Schuster, Heiko, Peper, Janet K., Bösmüller, Hans-Christian, Röhle, Kevin, Backert, Linus, Bilich, Tatjana, Ney, Britta, Löffler, Markus W., Kowalewski, Daniel J., Trautwein, Nico, Rabsteyn, Armin, Engler, Tobias, Braun, Sabine, Haen, Sebastian P., Walz, Juliane S., Schmid-Horch, Barbara, Brucker, Sara Y., Wallwiener, Diethelm, Kohlbacher, Oliver, Fend, Falko, Rammensee, Hans-Georg, Stevanovic, Stefan, Staebler, Annette, Wagner, Philipp

“…Immunotherapies, particularly checkpoint inhibitors, have set off a revolution in cancer therapy by releasing the power of the immune system. However, only…”
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Analysis of the sharpness of blades for food cutting by Schuldt, S., Arnold, G., Kowalewski, J., Schneider, Y., Rohm, H.

“…Although the sharpness of a blade is responsible for cutting performance, there is no single and unambiguous literature definition of sharpness. The blade…”
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Mapping the HLA Ligandome of Colorectal Cancer Reveals an Imprint of Malignant Cell Transformation by Löffler, Markus W, Kowalewski, Daniel J, Backert, Linus, Bernhardt, Jörg, Adam, Patrick, Schuster, Heiko, Dengler, Florian, Backes, Daniel, Kopp, Hans-Georg, Beckert, Stefan, Wagner, Silvia, Königsrainer, Ingmar, Kohlbacher, Oliver, Kanz, Lothar, Königsrainer, Alfred, Rammensee, Hans-Georg, Stevanović, Stefan, Haen, Sebastian P

“…Immune cell infiltrates have proven highly relevant for colorectal carcinoma prognosis, making colorectal cancer a promising candidate for immunotherapy…”
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Mapping the HLA ligandome landscape of acute myeloid leukemia: a targeted approach toward peptide-based immunotherapy by Berlin, C, Kowalewski, D J, Schuster, H, Mirza, N, Walz, S, Handel, M, Schmid-Horch, B, Salih, H R, Kanz, L, Rammensee, H-G, Stevanović, S, Stickel, J S

“…Identification of physiologically relevant peptide vaccine targets calls for the direct analysis of the entirety of naturally presented human leukocyte antigen…”
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Integrative -omics and HLA-ligandomics analysis to identify novel drug targets for ccRCC immunotherapy by Reustle, Anna, Di Marco, Moreno, Meyerhoff, Carolin, Nelde, Annika, Walz, Juliane S, Winter, Stefan, Kandabarau, Siahei, Büttner, Florian, Haag, Mathias, Backert, Linus, Kowalewski, Daniel J, Rausch, Steffen, Hennenlotter, Jörg, Stühler, Viktoria, Scharpf, Marcus, Fend, Falko, Stenzl, Arnulf, Rammensee, Hans-Georg, Bedke, Jens, Stevanović, Stefan, Schwab, Matthias, Schaeffeler, Elke

“…Clear cell renal cell carcinoma (ccRCC) is the dominant subtype of renal cancer. With currently available therapies, cure of advanced and metastatic ccRCC is…”
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An open-source computational and data resource to analyze digital maps of immunopeptidomes by Caron, Etienne, Espona, Lucia, Kowalewski, Daniel J, Schuster, Heiko, Ternette, Nicola, Alpízar, Adán, Schittenhelm, Ralf B, Ramarathinam, Sri H, Lindestam Arlehamn, Cecilia S, Chiek Koh, Ching, Gillet, Ludovic C, Rabsteyn, Armin, Navarro, Pedro, Kim, Sangtae, Lam, Henry, Sturm, Theo, Marcilla, Miguel, Sette, Alessandro, Campbell, David S, Deutsch, Eric W, Moritz, Robert L, Purcell, Anthony W, Rammensee, Hans-Georg, Stevanovic, Stefan, Aebersold, Ruedi

“…We present a novel mass spectrometry-based high-throughput workflow and an open-source computational and data resource to reproducibly identify and quantify…”
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A Non-interventional Clinical Trial Assessing Immune Responses After Radiofrequency Ablation of Liver Metastases From Colorectal Cancer by Löffler, Markus W, Nussbaum, Bianca, Jäger, Günter, Jurmeister, Philipp S, Budczies, Jan, Pereira, Philippe L, Clasen, Stephan, Kowalewski, Daniel J, Mühlenbruch, Lena, Königsrainer, Ingmar, Beckert, Stefan, Ladurner, Ruth, Wagner, Silvia, Bullinger, Florian, Gross, Thorben H, Schroeder, Christopher, Sipos, Bence, Königsrainer, Alfred, Stevanović, Stefan, Denkert, Carsten, Rammensee, Hans-Georg, Gouttefangeas, Cécile, Haen, Sebastian P

“…Radiofrequency ablation (RFA) is an established treatment option for malignancies located in the liver. RFA-induced irreversible coagulation necrosis leads to…”
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HLA ligandome analysis of primary chronic lymphocytic leukemia (CLL) cells under lenalidomide treatment confirms the suitability of lenalidomide for combination with T-cell-based immunotherapy by Nelde, Annika, Kowalewski, Daniel J., Backert, Linus, Schuster, Heiko, Werner, Jan-Ole, Klein, Reinhild, Kohlbacher, Oliver, Kanz, Lothar, Salih, Helmut R., Rammensee, Hans-Georg, Stevanović, Stefan, Walz, Juliane S.

“…Recent studies suggest that CLL is an immunogenic disease, which might be effectively targeted by antigen-specific T-cell-based immunotherapy. However, CLL is…”
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A new synthetic toll-like receptor 1/2 ligand is an efficient adjuvant for peptide vaccination in a human volunteer by Rammensee, Hans-Georg, Wiesmüller, Karl-Heinz, Chandran, P. Anoop, Zelba, Henning, Rusch, Elisa, Gouttefangeas, Cécile, Kowalewski, Daniel J., Di Marco, Moreno, Haen, Sebastian P., Walz, Juliane S., Gloria, Yamel Cardona, Bödder, Johanna, Schertel, Jill-Marie, Tunger, Antje, Müller, Luise, Kießler, Maximilian, Wehner, Rebekka, Schmitz, Marc, Jakobi, Meike, Schneiderhan-Marra, Nicole, Klein, Reinhild, Laske, Karoline, Artzner, Kerstin, Backert, Linus, Schuster, Heiko, Schwenck, Johannes, Weber, Alexander N. R., Pichler, Bernd J., Kneilling, Manfred, la Fougère, Christian, Forchhammer, Stephan, Metzler, Gisela, Bauer, Jürgen, Weide, Benjamin, Schippert, Wilfried, Stevanović, Stefan, Löffler, Markus W.

“…BackgroundWe previously showed that the bacterial lipopeptide Pam3Cys-Ser-Ser, meanwhile established as a toll-like receptor (TLR) 1/2 ligand, acts as a strong…”
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Characterization of the Canine MHC Class I DLA-8850101 Peptide Binding Motif as a Prerequisite for Canine T Cell Immunotherapy by Barth, Sharon M, Schreitmüller, Christian M, Proehl, Franziska, Oehl, Kathrin, Lumpp, Leonie M, Kowalewski, Daniel J, Di Marco, Moreno, Sturm, Theo, Backert, Linus, Schuster, Heiko, Stevanović, Stefan, Rammensee, Hans-Georg, Planz, Oliver

“…There are limitations in pre-clinical settings using mice as a basis for clinical development in humans. In cancer, similarities exist between humans and dogs;…”
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NMR Investigation of Chloromethane Complexes of Cryptophane‑A and Its Analogue with Butoxy Groups by Takacs, Z, Steiner, E, Kowalewski, J, Brotin, T

“…Host–guest complexes between cryptophane-A as host and dichloromethane and chloroform as guests are investigated using 1H and 13C NMR spectroscopy. Moreover, a…”
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CD74 regulates complexity of tumor cell HLA class II peptidome in brain metastasis and is a positive prognostic marker for patient survival by Zeiner, P S, Zinke, J, Kowalewski, D J, Bernatz, S, Tichy, J, Ronellenfitsch, M W, Thorsen, F, Berger, A, Forster, M T, Muller, A, Steinbach, J P, Beschorner, R, Wischhusen, J, Kvasnicka, H M, Plate, K H, Stefanović, S, Weide, B, Mittelbronn, M, Harter, P N

“…Despite multidisciplinary local and systemic therapeutic approaches, the prognosis for most patients with brain metastases is still dismal. The role of…”
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1H relaxation dispersion in solutions of nitroxide radicals: effects of hyperfine interactions with 14N and 15N nuclei by Kruk, D, Korpała, A, Kowalewski, J, Rössler, E A, Moscicki, J

“…(1)H relaxation dispersion of decalin and glycerol solutions of nitroxide radicals, 4-oxo-TEMPO-d(16)-(15)N and 4-oxo-TEMPO-d(16)-(14)N was measured in the…”
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Joint analysis of ESR lineshapes and 1H NMRD profiles of DOTA-Gd derivatives by means of the slow motion theory by Kruk, D, Kowalewski, J, Tipikin, D S, Tipikin, S, Freed, J H, Mościcki, M, Mielczarek, A, Port, M

“…The "Swedish slow motion theory" [Nilsson and Kowalewski, J. Magn. Reson. 146, 345 (2000)] applied so far to Nuclear Magnetic Relaxation Dispersion (NMRD)…”
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Contribution of hMTH1 to the Maintenance of 8-Oxoguanine Levels in Lung DNA of Non–Small-Cell Lung Cancer Patients by Speina, Elżbieta, Arczewska, Katarzyna D., Gackowski, Daniel, Zielińska, Maja, Siomek, Agnieszka, Kowalewski, Janusz, Oliński, Ryszard, Tudek, Barbara, Kuśmierek, Jarosław T.

“…Background: The level of 8-oxoguanine (8-oxoG), a general marker of oxidative DNA damage, in DNA is the result of both an equilibrium between the rates of its…”
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Radiative and nonradiative recombination of photoexcited excitons in multi-shell–coated CdSe/CdS/ZnS quantum dots by Fu, Y, Ågren, H, Kowalewski, J. M, Brismar, H, Wu, J, Yue, Y, Dai, N, Thylén, L

“…Colloidal quantum dots (QDs) have been widely studied for nanophotonics and bioimaging applications for which the lifetime of their fluorescence is of critical…”
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SARS-CoV-2-derived peptides define heterologous and COVID-19-induced T cell recognition by Nelde, Annika, Bilich, Tatjana, Heitmann, Jonas S., Maringer, Yacine, Salih, Helmut R., Roerden, Malte, Lübke, Maren, Bauer, Jens, Rieth, Jonas, Wacker, Marcel, Peter, Andreas, Hörber, Sebastian, Traenkle, Bjoern, Kaiser, Philipp D., Rothbauer, Ulrich, Becker, Matthias, Junker, Daniel, Krause, Gérard, Strengert, Monika, Schneiderhan-Marra, Nicole, Templin, Markus F., Joos, Thomas O., Kowalewski, Daniel J., Stos-Zweifel, Vlatka, Fehr, Michael, Rabsteyn, Armin, Mirakaj, Valbona, Karbach, Julia, Jäger, Elke, Graf, Michael, Gruber, Lena-Christin, Rachfalski, David, Preuß, Beate, Hagelstein, Ilona, Märklin, Melanie, Bakchoul, Tamam, Gouttefangeas, Cécile, Kohlbacher, Oliver, Klein, Reinhild, Stevanović, Stefan, Rammensee, Hans-Georg, Walz, Juliane S.

“…T cell immunity is central for the control of viral infections. To characterize T cell immunity, but also for the development of vaccines, identification of…”
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Purification and Identification of Naturally Presented MHC Class I and II Ligands by Nelde, Annika, Kowalewski, Daniel J, Stevanović, Stefan

“…The large-scale and in-depth identification of MHC class I- and II-presented peptides is indispensable for gaining insight into the fundamental rules of immune…”
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Fostering Advocacy, Developing Empathetic UX Bricoleurs: Ongoing Programmatic Assessment and Responsive Curriculum Design by Kowalewski, Scott J., Williamson, Bill

“…Introduction: As a field, we have tended to look at user-experience design (UXD) as a data-driven design process, anchored by usability studies, and anchored…”
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