Search Results - "Kovermann, Sina K."

TrxG and PcG Proteins but Not Methylated Histones Remain Associated with DNA through Replication by Petruk, Svetlana, Sedkov, Yurii, Johnston, Danika M., Hodgson, Jacob W., Black, Kathryn L., Kovermann, Sina K., Beck, Samantha, Canaani, Eli, Brock, Hugh W., Mazo, Alexander

“…Propagation of gene-expression patterns through the cell cycle requires the existence of an epigenetic mark that re-establishes the chromatin architecture of…”
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Delayed Accumulation of H3K27me3 on Nascent DNA Is Essential for Recruitment of Transcription Factors at Early Stages of Stem Cell Differentiation by Petruk, Svetlana, Cai, Jingli, Sussman, Robyn, Sun, Guizhi, Kovermann, Sina K., Mariani, Samanta A., Calabretta, Bruno, McMahon, Steven B., Brock, Hugh W., Iacovitti, Lorraine, Mazo, Alexander

“…Recruitment of transcription factors (TFs) to repressed genes in euchromatin is essential to activate new transcriptional programs during cell differentiation…”
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RNA polymerase II associates with active genes during DNA replication by Fenstermaker, Tyler K., Petruk, Svetlana, Kovermann, Sina K., Brock, Hugh W., Mazo, Alexander

“…The transcriptional machinery is thought to dissociate from DNA during replication. Certain proteins, termed epigenetic marks, must be transferred from parent…”
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Stepwise histone modifications are mediated by multiple enzymes that rapidly associate with nascent DNA during replication by Petruk, Svetlana, Black, Kathryn L., Kovermann, Sina K., Brock, Hugh W., Mazo, Alexander

“…The mechanism of epigenetic inheritance following DNA replication may involve dissociation of chromosomal proteins from parental DNA and reassembly on daughter…”
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