Search Results - "Kovalchuk, Sergey"

FlashPack: Fast and Simple Preparation of Ultrahigh-performance Capillary Columns for LC-MS[S] by Kovalchuk, Sergey I., Jensen, Ole N., Rogowska-Wrzesinska, Adelina

“…FlashPack is a fast and simple protocol for capillary column packing. It is developed for the classical 100 bars pressure bomb setup and ultrahigh sorbent…”
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Simulation of patient flow in multiple healthcare units using process and data mining techniques for model identification by Kovalchuk, Sergey V., Funkner, Anastasia A., Metsker, Oleg G., Yakovlev, Aleksey N.

“…[Display omitted] •A conceptual framework for hybrid simulation solution building is introduced.•Implementation of simulation solution is proposed as a…”
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Three-stage intelligent support of clinical decision making for higher trust, validity, and explainability by Kovalchuk, Sergey V., Kopanitsa, Georgy D., Derevitskii, Ilia V., Matveev, Georgy A., Savitskaya, Daria A.

“…[Display omitted] •A three-stage framework enhances clinical DSS trust, validity, and applicability.•Extension of data-driven model to enable norm referencing…”
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Simple In-House Ultra-High Performance Capillary Column Manufacturing with the FlashPack Approach by Kovalchuk, Sergey I, Ziganshin, Rustam, Shelukhina, Irina

“…Capillary ultra-high performance liquid chromatography (UHPLC) is currently a method of choice for the sample separation step in LC-MS-based proteomics…”
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Middle-Down Proteomic Analyses with Ion Mobility Separations of Endogenous Isomeric Proteoforms by Shliaha, Pavel V, Gorshkov, Vladimir, Kovalchuk, Sergey I, Schwämmle, Veit, Baird, Matthew A, Shvartsburg, Alexandre A, Jensen, Ole N

“…Biological functions of many proteins are governed by post-translational modifications (PTMs). In particular, the rich PTM complement in histones controls the…”
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Draft genome sequences of Hirudo medicinalis and salivary transcriptome of three closely related medicinal leeches by Babenko, Vladislav V, Podgorny, Oleg V, Manuvera, Valentin A, Kasianov, Artem S, Manolov, Alexander I, Grafskaia, Ekaterina N, Shirokov, Dmitriy A, Kurdyumov, Alexey S, Vinogradov, Dmitriy V, Nikitina, Anastasia S, Kovalchuk, Sergey I, Anikanov, Nickolay A, Butenko, Ivan O, Pobeguts, Olga V, Matyushkina, Daria S, Rakitina, Daria V, Kostryukova, Elena S, Zgoda, Victor G, Baskova, Isolda P, Trukhan, Vladimir M, Gelfand, Mikhail S, Govorun, Vadim M, Schiöth, Helgi B, Lazarev, Vassili N

“…Salivary cell secretion (SCS) plays a critical role in blood feeding by medicinal leeches, making them of use for certain medical purposes even today. We…”
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Unexpected Coelenterazine Degradation Products of Beroe abyssicola Photoprotein Photoinactivation by Burakova, Ludmila P, Lyakhovich, Maria S, Mineev, Konstantin S, Petushkov, Valentin N, Zagitova, Renata I, Tsarkova, Aleksandra S, Kovalchuk, Sergey I, Yampolsky, Ilia V, Vysotski, Eugene S, Kaskova, Zinaida M

“…Ca2+-regulated photoproteins of ctenophores lose bioluminescence activity when exposed to visible light. Little is known about the chemical nature of…”
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Distinct and diverse chromatin proteomes of ageing mouse organs reveal protein signatures that correlate with physiological functions by Oliviero, Giorgio, Kovalchuk, Sergey, Rogowska-Wrzesinska, Adelina, Schwämmle, Veit, Jensen, Ole N

“…Temporal molecular changes in ageing mammalian organs are of relevance to disease aetiology because many age-related diseases are linked to changes in the…”
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Yeast Ppz1 protein phosphatase toxicity involves the alteration of multiple cellular targets by Velázquez, Diego, Albacar, Marcel, Zhang, Chunyi, Calafí, Carlos, López-Malo, María, Torres-Torronteras, Javier, Martí, Ramón, Kovalchuk, Sergey I., Pinson, Benoit, Jensen, Ole N., Daignan-Fornier, Bertrand, Casamayor, Antonio, Ariño, Joaquín

“…Control of the protein phosphorylation status is a major mechanism for regulation of cellular processes, and its alteration often lead to functional disorders…”
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Hybrid Bayesian Network-Based Modeling: COVID-19-Pneumonia Case by Derevitskii, Ilia Vladislavovich, Mramorov, Nikita Dmitrievich, Usoltsev, Simon Dmitrievich, Kovalchuk, Sergey V.

“…The primary goal of this paper is to develop an approach for predicting important clinical indicators, which can be used to improve treatment. Using…”
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Lachesana tarabaevi, an expert in membrane-active toxins by Kuzmenkov, Alexey I, Sachkova, Maria Y, Kovalchuk, Sergey I, Grishin, Eugene V, Vassilevski, Alexander A

“…In the present study, we show that venom of the ant spider Lachesana tarabaevi is unique in terms of molecular composition and toxicity. Whereas venom of most…”
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Henlea earthworm bioluminescence comprises violet-blue BRET from tryptophan 2-carboxylate to deazaflavin cofactor by Petushkov, Valentin N., Vavilov, Matvey V., Khokhlova, Anastasia N., Zagitova, Renata I., Belozerova, Olga A., Shcheglov, Aleksandr S., Kovalchuk, Sergey I., Tsarkova, Aleksandra S., Rodionova, Natalia S., Yampolsky, Ilia V., Dubinnyi, Maxim A.

“…We recently identified the deazaflavin cofactor as a light emitter in novel bioluminescence (BL) system from Siberian earthworms Henlea sp. (Petushkov et al.,…”
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Translation initiation downstream from annotated start codons in human mRNAs coevolves with the Kozak context by Benitez-Cantos, Maria S, Yordanova, Martina M, O'Connor, Patrick B F, Zhdanov, Alexander V, Kovalchuk, Sergey I, Papkovsky, Dmitri B, Andreev, Dmitry E, Baranov, Pavel V

“…Eukaryotic translation initiation involves preinitiation ribosomal complex 5'-to-3' directional probing of mRNA for codons suitable for starting protein…”
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Thymidine utilisation pathway is a novel phenotypic switch of Mycoplasma hominis by Fisunov, Gleb Yu, Pobeguts, Olga V, Ladygina, Valentina G, Zubov, Alexandr I, Galyamina, Mariya A, Kovalchuk, Sergey I, Ziganshin, Rustam K, Evsyutina, Daria V, Matyushkina, Daria S, Butenko, Ivan O, Bukato, Olga N, Veselovsky, Vladimir A, Semashko, Tatiana A, Klimina, Ksenia M, Levina, Galina A, Barhatova, Olga I, Rakovskaya, Irina V

“…is a bacterium belonging to the class . It causes acute and chronic infections of the urogenital tract. The main features of this bacterium are an absence of…”
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The Role of Propionate-Induced Rearrangement of Membrane Proteins in the Formation of the Virulent Phenotype of Crohn's Disease-Associated Adherent-Invasive Escherichia coli by Pobeguts, Olga V, Galyamina, Maria A, Mikhalchik, Elena V, Kovalchuk, Sergey I, Smirnov, Igor P, Lee, Alena V, Filatova, Lyubov Yu, Sikamov, Kirill V, Panasenko, Oleg M, Gorbachev, Alexey Yu

“…Adhesive-invasive has been suggested to be associated with the development of Crohn's disease (CD). It is assumed that they can provoke the onset of the…”
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An Experimental Outlook on Quality Metrics for Process Modelling: A Systematic Review and Meta Analysis by Ireddy, Ashish T. S., Kovalchuk, Sergey V.

“…The ideology behind process modelling is to visualise lengthy event logs into simple representations interpretable to the end user. Classifying process models…”
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Domain Truncation in Hispidin Synthase Orthologs from Non-Bioluminescent Fungi Does Not Lead to Hispidin Biosynthesis by Palkina, Kseniia A, Balakireva, Anastasia V, Belozerova, Olga A, Chepurnykh, Tatiana V, Markina, Nadezhda M, Kovalchuk, Sergey I, Tsarkova, Aleksandra S, Mishin, Alexander S, Yampolsky, Ilia V, Sarkisyan, Karen S

“…Hispidin is a polyketide found in plants and fungi. In bioluminescent fungi, hispidin serves as a precursor of luciferin and is produced by hispidin synthases…”
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Structure elucidation of Keroplatus (Diptera:Keroplatidae) fungus gnat oxyluciferin by Kotlobay, Alexey A., Dubinnyi, Maxim A., Kovalchuk, Sergey I., Makhin, Aleksandr P., Miturich, Vasily S., Lyakhovich, Maria S., Fontaine, Danielle M., Southworth, Tara L., Shmygarev, Vladimir I., Yatskin, Oleg N., Branchini, Bruce R., Yampolsky, Ilia V., Kaskova, Zinaida M.

“…Bioluminescence of insects is a well-known natural phenomenon in the focus of interest of scientific research. While the mechanisms of bioluminescence in…”
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The Dynamics of Mycoplasma gallisepticum Nucleoid Structure at the Exponential and Stationary Growth Phases by Fisunov, Gleb Y., Zubov, Alexander I., Pobeguts, Olga V., Varizhuk, Anna M., Galyamina, Mariya A., Evsyutina, Daria V., Semashko, Tatiana A., Manuvera, Valentin A., Kovalchuk, Sergey I., Ziganshin, Rustam K., Barinov, Nicolay A., Klinov, Dmitry V., Govorun, Vadim M.

“…The structure and dynamics of bacterial nucleoids play important roles in regulating gene expression. Bacteria of class Mollicutes and, in particular,…”
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Proteome–Metabolome Profiling of Ovarian Cancer Ascites Reveals Novel Components Involved in Intercellular Communication by Shender, Victoria O., Pavlyukov, Marat S., Ziganshin, Rustam H., Arapidi, Georgij P., Kovalchuk, Sergey I., Anikanov, Nikolay A., Altukhov, Ilya A., Alexeev, Dmitry G., Butenko, Ivan O., Shavarda, Alexey L., Khomyakova, Elena B., Evtushenko, Evgeniy, Ashrafyan, Lev A., Antonova, Irina B., Kuznetcov, Igor N., Gorbachev, Alexey Yu, Shakhparonov, Mikhail I., Govorun, Vadim M.

“…Ovarian cancer ascites is a native medium for cancer cells that allows investigation of their secretome in a natural environment. This medium is of interest as…”
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