Search Results - "Koval, Lauren E."
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Wildfires and extracellular vesicles: Exosomal MicroRNAs as mediators of cross-tissue cardiopulmonary responses to biomass smoke
Published in Environment international (01-09-2022)“…[Display omitted] •Multiple wildfire-relevant exposure conditions were tested in mice.•Extracellular vesicles (EVs) were evaluated in circulating…”
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Chemical Mixtures in Household Environments: In Silico Predictions and In Vitro Testing of Potential Joint Action on PPARγ in Human Liver Cells
Published in Toxics (Basel) (19-04-2022)“…There are thousands of chemicals that humans can be exposed to in their everyday environments, the majority of which are currently understudied and lack…”
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Development of the InTelligence And Machine LEarning (TAME) Toolkit for Introductory Data Science, Chemical-Biological Analyses, Predictive Modeling, and Database Mining for Environmental Health Research
Published in Frontiers in toxicology (22-06-2022)“…Research in environmental health is becoming increasingly reliant upon data science and computational methods that can more efficiently extract information…”
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Wildfire Variable Toxicity: Identifying Biomass Smoke Exposure Groupings through Transcriptomic Similarity Scoring
Published in Environmental science & technology (06-12-2022)“…The prevalence of wildfires continues to grow globally with exposures resulting in increased disease risk. Characterizing these health risks remains difficult…”
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Environmental mixtures and breast cancer: identifying co-exposure patterns between understudied vs breast cancer-associated chemicals using chemical inventory informatics
Published in Journal of exposure science & environmental epidemiology (01-11-2022)“…Background Although evidence linking environmental chemicals to breast cancer is growing, mixtures-based exposure evaluations are lacking. Objective This study…”
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The Illustris simulation: supermassive black hole–galaxy connection beyond the bulge
Published in Monthly notices of the Royal Astronomical Society (01-02-2018)“…Abstract We study the spiral arm morphology of a sample of the local spiral galaxies in the Illustris simulation and explore the supermassive black hole–galaxy…”
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Predictive modeling of biological responses in the rat liver using in vitro Tox21 bioactivity: Benefits from high-throughput toxicokinetics
Published in Computational toxicology (01-05-2021)“…•Computational methods are needed to leverage in vitro models to inform toxicology.•Machine learning was integrated with toxicokinetic modeling to predict…”
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The Illustris Simulation: Supermassive Black Hole - Galaxy Connection Beyond the Bulge
Published 10-11-2017“…We study the spiral arm morphology of a sample of the local spiral galaxies in the Illustris simulation and explore the supermassive black hole - galaxy…”
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