Search Results - "Koval, Lauren"

Wildfires and extracellular vesicles: Exosomal MicroRNAs as mediators of cross-tissue cardiopulmonary responses to biomass smoke by Carberry, Celeste K., Koval, Lauren E., Payton, Alexis, Hartwell, Hadley, Ho Kim, Yong, Smith, Gregory J., Reif, David M., Jaspers, Ilona, Ian Gilmour, M, Rager, Julia E.

“…[Display omitted] •Multiple wildfire-relevant exposure conditions were tested in mice.•Extracellular vesicles (EVs) were evaluated in circulating…”
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Wildfire Variable Toxicity: Identifying Biomass Smoke Exposure Groupings through Transcriptomic Similarity Scoring by Koval, Lauren E., Carberry, Celeste K., Kim, Yong Ho, McDermott, Elena, Hartwell, Hadley, Jaspers, Ilona, Gilmour, M. Ian, Rager, Julia E.

“…The prevalence of wildfires continues to grow globally with exposures resulting in increased disease risk. Characterizing these health risks remains difficult…”
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Environmental mixtures and breast cancer: identifying co-exposure patterns between understudied vs breast cancer-associated chemicals using chemical inventory informatics by Koval, Lauren E., Dionisio, Kathie L., Friedman, Katie Paul, Isaacs, Kristin K., Rager, Julia E.

“…Background Although evidence linking environmental chemicals to breast cancer is growing, mixtures-based exposure evaluations are lacking. Objective This study…”
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The Illustris simulation: supermassive black hole–galaxy connection beyond the bulge by Mutlu-Pakdil, Burçin, Seigar, Marc S, Hewitt, Ian B, Treuthardt, Patrick, Berrier, Joel C, Koval, Lauren E

“…Abstract We study the spiral arm morphology of a sample of the local spiral galaxies in the Illustris simulation and explore the supermassive black hole–galaxy…”
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Correction to “Wildfire Variable Toxicity: Identifying Biomass Smoke Exposure Groupings through Transcriptomic Similarity Scoring” by Koval, Lauren E., Carberry, Celeste K., Kim, Yong Ho, McDermott, Elena, Hartwell, Hadley, Jaspers, Ilona, Gilmour, M. Ian, Rager, Julia E.

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Chemical Mixtures in Household Environments: In Silico Predictions and In Vitro Testing of Potential Joint Action on PPARγ in Human Liver Cells by Carberry, Celeste K, Turla, Toby, Koval, Lauren E, Hartwell, Hadley, Fry, Rebecca C, Rager, Julia E

“…There are thousands of chemicals that humans can be exposed to in their everyday environments, the majority of which are currently understudied and lack…”
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Predictive modeling of biological responses in the rat liver using in vitro Tox21 bioactivity: Benefits from high-throughput toxicokinetics by Ring, Caroline, Sipes, Nisha S., Hsieh, Jui-Hua, Carberry, Celeste, Koval, Lauren E., Klaren, William D., Harris, Mark A., Auerbach, Scott S., Rager, Julia E.

“…•Computational methods are needed to leverage in vitro models to inform toxicology.•Machine learning was integrated with toxicokinetic modeling to predict…”
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Development of the InTelligence And Machine LEarning (TAME) Toolkit for Introductory Data Science, Chemical-Biological Analyses, Predictive Modeling, and Database Mining for Environmental Health Research by Roell, Kyle, Koval, Lauren E., Boyles, Rebecca, Patlewicz, Grace, Ring, Caroline, Rider, Cynthia V., Ward-Caviness, Cavin, Reif, David M., Jaspers, Ilona, Fry, Rebecca C., Rager, Julia E.

“…Research in environmental health is becoming increasingly reliant upon data science and computational methods that can more efficiently extract information…”
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Extracellular Vesicles altered by a Per- and Polyfluoroalkyl Substance Mixture: In Vitro Dose-Dependent Release, Chemical Content, and MicroRNA Signatures involved in Liver Health by Carberry, Celeste K, Bangma, Jacqueline, Koval, Lauren, Keshava, Deepak, Hartwell, Hadley J, Sokolsky, Marina, Fry, Rebecca C, Rager, Julia E

“…Per- and polyfluoroalkyl substances (PFAS) have emerged as high priority contaminants due to their ubiquity and pervasiveness in the environment. Numerous PFAS…”
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Pharmacist and physician perception of barriers to collaborative drug therapy management in Missouri by Koval, Lauren L., Jeon, Michelle, Gattas, Nicole M.

“…Collaborative drug therapy management (CDTM) rules were implemented in 2012 in Missouri, but community pharmacists are currently not working with physicians to…”
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Criteria pollutant impacts of volatile chemical products informed by near-field modelling by Qin, Momei, Murphy, Benjamin N., Isaacs, Kristin K., McDonald, Brian C., Lu, Quanyang, McKeen, Stuart A., Koval, Lauren, Robinson, Allen L., Efstathiou, Christos, Allen, Chris, Pye, Havala O. T.

“…Consumer, industrial and commercial product use is a source of exposure to potentially hazardous chemicals. In addition, cleaning agents, personal care…”
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A multi‐omic approach identifies an autism spectrum disorder (ASD) regulatory complex of functional epimutations in placentas from children born preterm by Freedman, Anastasia N., Clark, Jeliyah, Eaves, Lauren A., Roell, Kyle, Oran, Ali, Koval, Lauren, Rager, Julia, Santos, Hudson P., Kuban, Karl, Joseph, Robert M., Frazier, Jean, Marsit, Carmen J., Burt, Amber A., O'Shea, T. Michael, Fry, Rebecca C.

“…Children born preterm are at heightened risk of neurodevelopmental impairments, including Autism Spectrum Disorder (ASD). The placenta is a key regulator of…”
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The Illustris Simulation: Supermassive Black Hole - Galaxy Connection Beyond the Bulge by Mutlu-Pakdil, Burçin, Seigar, Marc S, Hewitt, Ian B, Treuthardt, Patrick, Berrier, Joel C, Koval, Lauren E

“…We study the spiral arm morphology of a sample of the local spiral galaxies in the Illustris simulation and explore the supermassive black hole - galaxy…”
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