Search Results - "Kovacs, Sandor J"

Vortex Ring Formation in the Left Ventricle of the Heart: Analysis by 4D Flow MRI and Lagrangian Coherent Structures by Töger, Johannes, Kanski, Mikael, Carlsson, Marcus, Kovács, Sándor J., Söderlind, Gustaf, Arheden, Håkan, Heiberg, Einar

“…Recent studies suggest that vortex ring formation during left ventricular (LV) rapid filling is an optimized mechanism for blood transport, and that the volume…”
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Long-Term Caloric Restriction Ameliorates the Decline in Diastolic Function in Humans by Meyer, Timothy E., Kovács, Sándor J., Ehsani, Ali A., Klein, Samuel, Holloszy, John O., Fontana, Luigi

“…Long-Term Caloric Restriction Ameliorates the Decline in Diastolic Function in Humans Timothy E. Meyer, Sándor J. Kovács, Ali A. Ehsani, Samuel Klein, John O…”
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The role of left atrial function in diastolic heart failure by Appleton, Christopher P, Kovács, Sándor J

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Kinematic Modeling-based Left Ventricular Diastatic (Passive) Chamber Stiffness Determination with In-Vivo Validation by Mossahebi, Sina, Kovács, Sándor J.

“…The slope of the diastatic pressure–volume relationship (D-PVR) defines passive left ventricular (LV) stiffness Although is a relative measure, cardiac…”
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Early Left Ventricular Diastolic Function Quantitation Using Directional Impedances by Ghosh, Erina, Kovács, Sándor J.

“…Impedance has been used in vascular biology to characterize the frequency dependent opposition the circulatory system presents to blood flow in response to a…”
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Duration of diastole and its phases as a function of heart rate during supine bicycle exercise by Chung, Charles S, Karamanoglu, Mustafa, Kovács, Sándor J

“…The duration of diastole can be defined in terms of mechanical events. Mechanical diastolic duration (MDD) is comprised by the phases of early rapid filling (E…”
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The diastatic pressure-volume relationship is not the same as the end-diastolic pressure-volume relationship by Zhang, Wei, Kovács, Sándor J

“…The end-diastolic pressure-volume (P-V) relationship (EDPVR) is routinely used to determine the passive left ventricular (LV) stiffness, although the diastatic…”
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Load-independent index of diastolic filling: model-based derivation with in vivo validation in control and diastolic dysfunction subjects by Shmuylovich, Leonid, Kovacs, Sandor J

“…Cardiovascular Biophysics Laboratory, Washington University School of Medicine, St. Louis, Missouri Submitted 12 October 2005 ; accepted in final form 20 March…”
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E-wave deceleration time may not provide an accurate determination of LV chamber stiffness if LV relaxation/viscoelasticity is unknown by Shmuylovich, Leonid, Kovács, Sándor J

“…Average left ventricular (LV) chamber stiffness (Delta P(avg)/Delta V(avg)) is an important diastolic function index. An E-wave-based determination of Delta…”
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Physical determinants of left ventricular isovolumic pressure decline: model prediction with in vivo validation by Chung, Charles S, Kovács, Sándor J

“…The rapid decline in pressure during isovolumic relaxation (IVR) is traditionally fit algebraically via two empiric indexes: tau, the time constant of IVR, or…”
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The effects of caloric restriction- and exercise-induced weight loss on left ventricular diastolic function by Riordan, Matt M, Weiss, Edward P, Meyer, Timothy E, Ehsani, Ali A, Racette, Susan B, Villareal, Dennis T, Fontana, Luigi, Holloszy, John O, Kovács, Sándor J

“…Little is known about the effects of weight loss on diastolic function. Furthermore, it is not known whether both caloric restriction (CR)- and exercise…”
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How the (Pediatric) Heart Works When It Contracts: Application of Left Ventricular “Isovolumic Acceleration” as a Load-Independent Index of Contractility by Kovacs, Sandor J

“…Pediatric cardiologists, indeed all cardiologists, are often confronted with the challenge of clinical decision-making based, in part, on assessment of…”
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The E-Wave Delayed Relaxation Pattern to LV Pressure Contour Relation: Model-Based Prediction With in vivo Validation by Zhang, Wei, Shmuylovich, Leonid, Kovács, Sándor J

“…Abstract The transmitral Doppler E-wave “delayed relaxation” (DR) pattern is an established sign of diastolic dysfunction (DD). Furthermore, chambers…”
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The quest for load‐independent left ventricular chamber properties: exploring the normalized pressure–volume loop by Kohli, Keshav, Kovács, Sándor J.

“…Left ventricular (LV) pressure–volume (P–V) loop analysis is the gold standard for chamber function assessment. To advance beyond traditional P–V and pressure…”
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Stiffness and relaxation components of the exponential and logistic time constants may be used to derive a load-independent index of isovolumic pressure decay by Shmuylovich, Leonid, Kovács, Sándor J

“…In current practice, empirical parameters such as the monoexponential time constant tau or the logistic model time constant tauL are used to quantitate…”
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The vortex formation time to diastolic function relation: assessment of pseudonormalized versus normal filling by Ghosh, Erina, Kovács, Sándor J.

“…In early diastole, the suction pump feature of the left ventricle opens the mitral valve and aspirates atrial blood. The ventricle fills via a blunt profiled…”
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Left atrial conduit volume is generated by deviation from the constant-volume state of the left heart: a combined MRI-echocardiographic study by Bowman, Andrew W, Kovács, Sándor J

“…Although modeling the four-chambered heart as a constant-volume pump successfully predicts causal physiological relationships between cardiac indexes…”
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The Age Dependence of Left Ventricular Filling Efficiency by Zhang, Wei, MA, Kovács, Sándor J., PhD, MD

“…Abstract Echocardiography has emerged as the preferred modality by which diastolic function (DF) is assessed for clinical or research purposes…”
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The Diastolic Function to Cyclic Variation of Myocardial Ultrasonic Backscatter Relation: The Influence of Parametrized Diastolic Filling (PDF) Formalism Determined Chamber Properties by Lloyd, Christopher W, Shmuylovich, Leonid, Holland, Mark R, Miller, James G, Kovács, Sándor J

“…Abstract Myocardial tissue characterization represents an extension of currently available echocardiographic imaging. The systematic variation of backscattered…”
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Frequency-based analysis of the early rapid filling pressure-flow relation elucidates diastolic efficiency mechanisms by Wu, Yue, Kovács, Sándor J

“…Stiffness- and relaxation-based diastolic function (DF) assessment can characterize the presence, severity, and mechanism of dysfunction. Although…”
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