Search Results - "Kovacs, Magdolna"

TNF inhibitors significantly attenuate the humoral immune response to COVID-19 vaccination in patients with rheumatoid arthritis by Schäfer, Arne, Kovacs, Magdolna S, Eder, Anna, Nigg, Axel, Feuchtenberger, Martin

“…Abstract Objective Several studies on the immunogenicity of vaccination against coronavirus disease 2019 (COVID-19) in patients with immune-mediated…”
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New derivatives of GnRH as potential anticancer therapeutic agents by Mezo, Gábor, Manea, Marilena, Szabí, Ildikí, Vincze, Borbála, Kovács, Magdolna

“…GnRH (gonadotropin-releasing hormone), a decapeptide produced by the hypothalamus, plays an important role in the reproduction by regulating the…”
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A correlation of endocrine and anticancer effects of some antagonists of GHRH by Kovács, Magdolna, Schally, Andrew V., Hohla, Florian, Rick, Ferenc G., Pozsgai, Éva, Szalontay, Luca, Varga, József L., Zarándi, Márta

“…▶ Human glioblastoma cell lines strongly express pGHRH-Rs. ▶ The anticancer activity of GHRH antagonists in glioblastomas reflects their endocrine potency. ▶…”
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Endocrine and antineoplastic actions of growth hormone-releasing hormone antagonists by Kovács, Magdolna, Schally, Andrew V, Varga, József L, Zarándi, Márta

“…Potent antagonists of growth hormone-releasing hormone (GHRH) have been developed for the treatment of disorders caused by excessive GHRH or growth hormone…”
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Regulation of pituitary inhibin/activin subunits and follistatin gene expression by GnRH in female rats by Popovics, Petra, Rekasi, Zoltan, Stewart, Alan J, Kovacs, Magdolna

“…Pituitary inhibin B, activin B, and follistatin are local regulators of FSH. Activin B is a homodimeric molecule (βB–βB), while inhibin B contains an α and a…”
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Luteinizing hormone-releasing hormone (LH-RH) antagonist Cetrorelix down-regulates the mRNA expression of pituitary receptors for LH-RH by counteracting the stimulatory effect of endogenous LH-RH by Kovacs, Magdolna, Schally, Andrew V., Csernus, Balazs, Rekasi, Zoltan

“…The mechanisms through which LH-RH antagonists suppress gonadotroph functions and LH-RH receptor (LH-RH-R) production are incompletely understood. To elucidate…”
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Increased Activity of Antagonists of Growth Hormone-Releasing Hormone Substituted at Positions 8, 9, and 10 by Varga, Jozsef L., Schally, Andrew V., Horvath, Judit E., Kovacs, Magdolna, Halmos, Gabor, Groot, Kate, Toller, Gabor L., Rekasi, Zoltan, Zarandi, Marta

“…Antagonists of human growth hormone-releasing hormone (hGHRH) with increased potency and improved enzymatic and chemical stability are needed for potential…”
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Comparison of Mechanisms of Action of Luteinizing Hormone-Releasing Hormone (LHRH) Antagonist Cetrorelix and LHRH Agonist Triptorelin on the Gene Expression of Pituitary LHRH Receptors in Rats by Kovacs, Magdolna, Schally, Andrew V.

“…The mechanisms through which luteinizing hormone (LH)-releasing hormone (LHRH) antagonists suppress pituitary gonadotroph functions and LHRH-receptor (LHRH-R)…”
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Lipopeptide Antagonists of Growth Hormone-Releasing Hormone with Improved Antitumor Activities by Zarandi, Marta, Varga, Jozsef L., Schally, Andrew V., Horvath, Judit E., Toller, Gabor L., Kovacs, Magdolna, Letsch, Markus, Groot, Kate, Armatis, Patricia, Halmos, Gabor

“…Antagonists of growth hormone-releasing hormone (GHRH) synthesized previously inhibit proliferation of various human cancers, but derivatisation with fatty…”
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The virtuous cycle: the reinforcing relationship between L2 attitudes and L2 use among young Italian-speaking South-Tyrolese by Marton, Enikő, Kovács, Magdolna, Vincze, László

“…Aims and Objectives: The aim of the present study is to address the reciprocal relationship between L2 attitudes and L2 use in a bilingual setting among…”
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Luteinizing Hormone-Releasing Hormone (LH-RH) Antagonist Cetrorelix Down-Regulates the mRNA Expression of Pituitary Receptors for LH-RH by Counteracting the Stimulatory Effect of Endogenous LH-RH by Kovacs, Magdolna, Schally, Andrew V., Csernus, Balazs, Rekasi, Zoltan

“…The mechanisms through which LH-RH antagonists suppress gonadotroph functions and LH-RH receptor (LH-RH-R) production are incompletely understood. To elucidate…”
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Effects of Long-Term Treatment with the Luteinizing Hormone-Releasing Hormone (LHRH) Agonist Decapeptyl and the LHRH Antagonist Cetrorelix on the Levels of Pituitary LHRH Receptors and Their mRNA Expression in Rats by Horvath, Judit E., Bajo, Ana M., Schally, Andrew V., Kovacs, Magdolna, Herbert, Francine, Groot, Kate

“…The effects of depot formulations of the luteinizing hormone-releasing hormone (LHRH) agonist Decapeptyl (25 µg/day) for 30 days or LHRH antagonist Cetrorelix…”
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Chemical and stable isotope composition of recent hot-water travertines and associated thermal waters, from Egerszalók, Hungary: Depositional facies and non-equilibrium fractionation by Kele, Sándor, Demény, Attila, Siklósy, Zoltán, Németh, Tibor, Tóth, Mária, Kovács, Magdolna B.

“…Combined petrographical, mineralogical, geochemical and stable isotope analyses were conducted on an actively forming Egerszalók Travertine mound to determine…”
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Janus kinase (JAK) inhibitors significantly reduce the humoral vaccination response against SARS-CoV-2 in patients with rheumatoid arthritis by Schäfer, Arne, Kovacs, Magdolna Szilvia, Eder, Anna, Nigg, Axel, Feuchtenberger, Martin

“…Objectives Recently, a number of studies have explored the possible attenuation of the immune response by disease-modifying antirheumatic drugs (DMARDs) in…”
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Methotrexate significantly reduces the humoral vaccination response against SARS-CoV-2 in older but not younger patients with rheumatoid arthritis by Feuchtenberger, Martin, Kovacs, Magdolna Szilvia, Eder, Anna, Nigg, Axel, Schäfer, Arne

“…To assess the humoral response to vaccination against SARS-CoV-2 in patients with rheumatoid arthritis treated with methotrexate (MTX). In total, 142 fully…”
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Comparative in vitro biological evaluation of daunorubicin containing GnRH-I and GnRH-II conjugates developed for tumor targeting by Szabó, Ildikó, Bősze, Szilvia, Orbán, Erika, Sipos, Éva, Halmos, Gábor, Kovács, Magdolna, Mező, Gábor

“…Hormone based drug targeting is a promising tool for selective tumor therapy. In this study, synthesis and systematic comparative biological evaluation of…”
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Recovery of Pituitary Function after Treatment with a Targeted Cytotoxic Analog of Luteinizing Hormone-Releasing Hormone by Kovacs, Magdolna, Schally, Andrew V., Nagy, Attila, Koppan, Miklos, Groot, Kate

“…Recently, we developed a targeted cytotoxic analog AN-207 of luteinizing hormone-releasing hormone (LH-RH), consisting of an intensely potent derivative of…”
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Prioritising Appointments by Telephone Interview: Duration from Symptom Onset to Appointment Request Predicts Likelihood of Inflammatory Rheumatic Disease by Feuchtenberger, Martin, Kovacs, Magdolna Szilvia, Nigg, Axel, Schäfer, Arne

“…This study aims to determine the rate of inflammatory rheumatic diseases (IRDs) in a cohort of initial referrals and the efficacy of prioritising appointments…”
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Longitudinal assessment of liver stiffness using ARFI technique does not support increased risk of fibrosis in rheumatoid arthritis patients on methotrexate by Schäfer, Arne, Kovacs, Magdolna Szilvia, Eder, Anna, Nigg, Axel, Feuchtenberger, Martin

“…To assess the liver stiffness in patients with rheumatoid arthritis treated with methotrexate monotherapy using non-invasive, ultrasound-based elastography…”
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Patient-Reported Outcomes of Depression and Fibromyalgia Symptoms Do Not Predict Non-Inflammatory versus Inflammatory Diagnoses at Initial Rheumatology Consultation by Schäfer, Arne, Kovacs, Magdolna Szilvia, Nigg, Axel, Feuchtenberger, Martin

“…The objective of this study was to assess the potential value of patient-reported outcomes (PROs) of depression, fibromyalgia symptoms, and pain in predicting…”
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