Search Results - "Kovacs, D"

Cell biology of the NCL proteins: What they do and don't do by Cárcel-Trullols, Jaime, Kovács, Attila D., Pearce, David A.

“…The fatal, primarily childhood neurodegenerative disorders, neuronal ceroid lipofuscinoses (NCLs), are currently associated with mutations in 13 genes. The…”
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The Human Synaptic Vesicle Protein, SV2A, Functions as a Galactose Transporter in Saccharomyces cerevisiae by Madeo, Marianna, Kovács, Attila D., Pearce, David A.

“…SV2A is a synaptic vesicle membrane protein expressed in neurons and endocrine cells and involved in the regulation of neurotransmitter release. Although the…”
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Untangling the Causal Links between Satellite Vegetation Products and Environmental Drivers on a Global Scale by the Granger Causality Method by Kovács, Dávid D., Amin, Eatidal, Berger, Katja, Reyes-Muñoz, Pablo, Verrelst, Jochem

“…The Granger Causality (GC) statistical test explores the causal relationships between different time series variables. By employing the GC method, the…”
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That dog won’t fit: body size awareness in dogs by Lenkei, R., Faragó, T., Kovács, D., Zsilák, B., Pongrácz, P.

“…With very few exceptions, no coherent model of representing the self exists for nonhuman species. According to our hypothesis, understanding of the Self as an…”
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Mitochondrial protective effects of PARP-inhibition in hypertension-induced myocardial remodeling and in stressed cardiomyocytes by Ordog, K., Horvath, O., Eros, K., Bruszt, K., Toth, Sz, Kovacs, D., Kalman, N., Radnai, B., Deres, L., Gallyas, F., Toth, K., Halmosi, R.

“…During oxidative stress mitochondria become the main source of endogenous reactive oxygen species (ROS) production. In the present study, we aimed to clarify…”
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Cloud-Free Global Maps of Essential Vegetation Traits Processed from the TOA Sentinel-3 Catalogue in Google Earth Engine by Kovács, Dávid D., Reyes-Muñoz, Pablo, Salinero-Delgado, Matías, Mészáros, Viktor Ixion, Berger, Katja, Verrelst, Jochem

“…Global mapping of essential vegetation traits (EVTs) through data acquired by Earth-observing satellites provides a spatially explicit way to analyze the…”
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Acidified drinking water improves motor function, prevents tremors and changes disease trajectory in Cln2R207X mice, a model of late infantile Batten disease by Kovács, Attila D., Gonzalez Hernandez, Jose L., Pearce, David A.

“…Batten disease is a group of mostly pediatric neurodegenerative lysosomal storage disorders caused by mutations in the CLN1–14 genes. We have recently shown…”
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Isotretinoin is indirectly effective in sebocytes by Kovács, D., Hegyi, K., Szegedi, A., Deák, D., Póliska, Sz, Rühl, R., Zouboulis, C.C., Törőcsik, D.

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Intrinsically disordered proteins undergo and assist folding transitions in the proteome by Kovacs, D., Szabo, B., Pancsa, R., Tompa, P.

“…► Many proteins and protein domains are intrinsically disordered (IDPs). ► IDPs often undergo induced folding upon binding to a partner. ► Induced folding can…”
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Effects of pioglitazone on the differentiation and inflammation in vitiligo keratinocytes by Bastonini, E., Kovacs, D., Briganti, S., Ottaviani, M., D'Arino, A., Migliano, E., Pacifico, A., Iacovelli, P., Picardo, M.

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Finding the most appropriate mouse model of juvenile CLN3 (Batten) disease for therapeutic studies: the importance of genetic background and gender by Kovács, Attila D, Pearce, David A

“…Mutations in the CLN3 gene cause a fatal neurodegenerative disorder: juvenile CLN3 disease, also known as juvenile Batten disease. The two most commonly…”
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Evolution of IFMIF-DONES' heart: System overview of the Test Cell by Zsákai, A., Meléndez, C., Becerril, S., Dézsi, T., Kovács, D., Simon, R.S., Korossy-Khayll, A., Oravecz, D.Z., Katona, I., Castellanos, J., Serikov, A., Qiu, Y., Micicché, G., García, M., Ibarra, A.

“…The IFMIF-DONES Facility is built with the purpose of irradiating materials under DEMO Tokamak-like conditions and is a first-of-a-kind project that is…”
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Role of the Lysosomal Membrane Protein, CLN3, in the Regulation of Cathepsin D Activity by Cárcel‐Trullols, Jaime, Kovács, Attila D., Pearce, David A.

“…ABSTRACT Among Neuronal Ceroid Lipofuscinoses (NCLs), which are childhood fatal neurodegenerative disorders, the juvenile onset form (JNCL) is the most common…”
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Changes in motor behavior, neuropathology, and gut microbiota of a Batten disease mouse model following administration of acidified drinking water by Johnson, Tyler B., Langin, Logan M., Zhao, Jing, Weimer, Jill M., Pearce, David A., Kovács, Attila D.

“…CLN3 mutations cause the fatal neurodegenerative disorder, CLN3 Batten disease. The Cln3 −/− mouse model displays characteristic features of the human disease…”
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A novel porcine model of ataxia telangiectasia reproduces neurological features and motor deficits of human disease by Beraldi, Rosanna, Chan, Chun-Hung, Rogers, Christopher S, Kovács, Attila D, Meyerholz, David K, Trantzas, Constantin, Lambertz, Allyn M, Darbro, Benjamin W, Weber, Krystal L, White, Katherine A M, Rheeden, Richard V, Kruer, Michael C, Dacken, Brian A, Wang, Xiao-Jun, Davis, Bryan T, Rohret, Judy A, Struzynski, Jason T, Rohret, Frank A, Weimer, Jill M, Pearce, David A

“…Ataxia telangiectasia (AT) is a progressive multisystem disorder caused by mutations in the AT-mutated (ATM) gene. AT is a neurodegenerative disease primarily…”
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Role of fibroblast-derived growth factors in regulating hyperpigmentation of solar lentigo by Kovacs, D., Cardinali, G., Aspite, N., Cota, C., Luzi, F., Bellei, B., Briganti, S., Amantea, A., Torrisi, M.R., Picardo, M.

“…Summary Background  Cutaneous pigmentation is regulated by a complex melanogenic network in which both keratinocytes and fibroblasts synthesize growth factors…”
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A tailored Cln3Q352X mouse model for testing therapeutic interventions in CLN3 Batten disease by Langin, Logan, Johnson, Tyler B., Kovács, Attila D., Pearce, David A., Weimer, Jill M.

“…CLN3 Batten disease (CLN3 disease) is a pediatric lysosomal storage disorder that presents with progressive blindness, motor and cognitive decline, seizures,…”
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Protein-Water and Protein-Buffer Interactions in the Aqueous Solution of an Intrinsically Unstructured Plant Dehydrin: NMR Intensity and DSC Aspects by Tompa, P., Bánki, P., Bokor, M., Kamasa, P., Kovács, D., Lasanda, G., Tompa, K.

“…Proton NMR intensity and differential scanning calorimetry measurements were carried out on an intrinsically unstructured late embryogenesis abundant protein,…”
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Multi-Center Follow-up Study to Develop a Classification System Which Differentiates Mucinous Cystic Neoplasm of the Liver and Benign Hepatic Cyst Using Machine Learning by Hardie, Andrew D, Chamberlin, Jordan H, Boyum, James H, Sharbidre, Kedar G, Petrocelli, Robert, Flemming, Brian P, Zahid, Mohd, Venkatesh, Sudhakar K, Mruthyunjayappa, Smitha, Hajdu, Cristina H, Kovacs, Mark D

“…RATIONALE AND OBJECTIVESTo date, no clinically useful classification system has been developed for reliably differentiating mucinous cystic neoplasm (MCN) from…”
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Combined dual energy and iterative metal artefact reduction for PET/CT in head and neck cancer by Kovacs, D G, Ladefoged, C N, Berthelsen, A K, Fischer, B M, Andersen, F L

“…Metal artefacts in PET/CT images hamper diagnostic accuracy in head and neck cancer (HNC). The aim of this study is to characterise the clinical effects of…”
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