Search Results - "Kovacic, Hervé O"

Pathological Impact of Redox Post-Translational Modifications by Chahla, Charbel, Kovacic, Hervé, Ferhat, Lotfi, Leloup, Ludovic

“…Oxidative stress is involved in the development of several pathologies. The different reactive oxygen species (ROS) produced during oxidative stress are at the…”
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Parkinson disease: Protective role and function of neuropeptides by Tabikh, Mireille, Chahla, Charbel, Okdeh, Nathalie, Kovacic, Herve, Sabatier, Jean-Marc, Fajloun, Ziad

“…•Involvement of neuropeptides present in the CNS on Parkinson's disease (PD);•Distribution and dysregulation of neuropeptides are strongly associated with the…”
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Leptin Promotes Prostate Cancer Proliferation and Migration by Stimulating STAT3 Pathway by Gorrab, Amal, Pagano, Alessandra, Ayed, Khouloud, Chebil, Mohamed, Derouiche, Amine, Kovacic, Hervé, Gati, Asma

“…To better understand the link between obesity and prostate cancer (PC) aggressiveness, we investigate the role of leptin, an obesity associated adipokine, and…”
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Angiotensin II Type I Receptor (AT1R): The Gate towards COVID-19-Associated Diseases by El-Arif, George, Khazaal, Shaymaa, Farhat, Antonella, Harb, Julien, Annweiler, Cédric, Wu, Yingliang, Cao, Zhijian, Kovacic, Hervé, Abi Khattar, Ziad, Fajloun, Ziad, Sabatier, Jean-Marc

“…The binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein to its cellular receptor, the angiotensin-converting enzyme…”
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The Renin-Angiotensin System: A Key Role in SARS-CoV-2-Induced COVID-19 by El-Arif, George, Farhat, Antonella, Khazaal, Shaymaa, Annweiler, Cédric, Kovacic, Hervé, Wu, Yingliang, Cao, Zhijian, Fajloun, Ziad, Khattar, Ziad Abi, Sabatier, Jean Marc

“…The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), was first identified in…”
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Counter-Regulatory Renin-Angiotensin System: An Important Line of Research to Understand and Limit the Severity of COVID-19 by Annweiler, Cédric, Cao, Zhijian, Papon, Nicolas, Kovacic, Hervé, Sabatier, Jean-Marc

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Inhibitor of Apoptosis Proteins Determine Glioblastoma Stem-Like Cells Fate in an Oxygen-Dependent Manner by Soubéran, Aurélie, Cappaï, Jessica, Chocry, Mathieu, Nuccio, Christopher, Raujol, Julie, Colin, Carole, Lafitte, Daniel, Kovacic, Hervé O, Baeza-Kallee, Nathalie, Rougon, Genevieve, Figarella‑branger, Dominique, Tchoghandjian, Aurelie

“…In glioblastomas, apoptosis inhibitor proteins (IAPs) are involved in apoptotic and non-apoptotic processes. We previously showed that IAPs inhibition induced…”
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Tau Regulates Glioblastoma Progression, 3D Cell Organization, Growth and Migration via the PI3K-AKT Axis by Pagano, Alessandra, Breuzard, Gilles, Parat, Fabrice, Tchoghandjian, Aurélie, Figarella-Branger, Dominique, De Bessa, Tiphany Coralie, Garrouste, Françoise, Douence, Alexis, Barbier, Pascale, Kovacic, Hervé

“…The Microtubule-Associated Protein Tau is expressed in several cancers, including low-grade gliomas and glioblastomas. We have previously shown that Tau is…”
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SARS-CoV-2-Induced Neurological Disorders in Symptomatic Covid-19 and Long Covid Patients: Key Role of Brain Renin-Angiotensin System by Fajloun, Ziad, Kovacic, Hervé, Annweiler, Cédric, Wu, Yingliang, Cao, Zhijian, Sabatier, Jean-Marc

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Subverted regulation of Nox1 NADPH oxidase-dependent oxidant generation by protein disulfide isomerase A1 in colon carcinoma cells with overactivated KRas by De Bessa, Tiphany Coralie, Pagano, Alessandra, Moretti, Ana Iochabel Soares, Oliveira, Percillia Victoria Santos, Mendonça, Samir Andrade, Kovacic, Herve, Laurindo, Francisco Rafael Martins

“…Protein disulfide isomerases including PDIA1 are implicated in cancer progression, but underlying mechanisms are unclear. PDIA1 is known to support vascular…”
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Editorial: Venoms, animal and microbial toxins, volume II by Cao, Zhijian, Shahbazzadeh, Delavar, Kovacic, Hervé, McNutt, Patrick Michael, Wang, Jing-Lin, Wulff, Heike, Utkin, Yuri, Sabatier, Jean-Marc

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Oxidation of Ca 2+ -Binding Domain of NADPH Oxidase 5 (NOX5): Toward Understanding the Mechanism of Inactivation of NOX5 by ROS by Petrushanko, Irina A, Lobachev, Vladimir A, Kononikhin, Alexey A, Makarov, Alexander A, Devred, François O, Kovacic, Hervé O, Kubatiev, Aslan A, Tsvetkov, Philipp O

“…NOX5 protein, one of the most active generators of reactive oxygen species (ROS), plays an important role in many processes, including regulation of cell…”
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Isolation of an Anti-Tumour Disintegrin: Dabmaurin-1, a Peptide Lebein-1-Like, from Daboia mauritanica Venom by Chalier, Florence, Mugnier, Laura, Tarbe, Marion, Aboudou, Soioulata, Villard, Claude, Kovacic, Hervé, Gigmes, Didier, Mansuelle, Pascal, de Pomyers, Harold, Luis, José, Mabrouk, Kamel

“…In the soft treatment of cancer tumours, consequent downregulation of the malignant tissue angiogenesis constitutes an efficient way to stifle tumour…”
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Editorial: Venoms, Animal and Microbial Toxins by Cao, Zhijian, Wang, Jing-Lin, McNutt, Patrick Michael, Utkin, Yuri N., Shahbazzadeh, Delavar, Wulff, Heike, Kovacic, Hervé, Sabatier, Jean-Marc

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Metformin-Derived Hybrid Molecules for Glioblastoma Treatment by Delehedde, Caroline, Chocry, Mathieu, Thétiot-Laurent, Sophie, Garrouste, Françoise, Culcasi, Marcel, Kovacic, Hervé O, Pietri, Sylvia

“…Glioblastoma is the most common cerebral tumor in adults. The median survival of glioblastoma patients is 12 months. Metformin is a biguanide used as a…”
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Patupilone-induced apoptosis is mediated by mitochondrial reactive oxygen species through Bim relocalization to mitochondria by Khawaja, N R, Carré, M, Kovacic, H, Estève, M A, Braguer, D

“…Among the new microtubule-targeted agents, the epothilone family of molecules has shown promising anticancer potential, and clinical trials are currently…”
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L’atp et l’utp inhibent la dynamique de l’actine et des lamellipodes ainsi que la migration de cellules épithéliales humaines via l’activation de la voie p2y2/gq by Taboubi, S., Milanini, J., Parat, F., Bueckly, E., Huiart, X., Takasaki, J., Kovacic, H., Hubaud, J.C., Lehmann, M.

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