Search Results - "Kovárík, J"

Osteoradionecrosis after treatment of head and neck cancer: a comprehensive analysis of risk factors with a particular focus on role of dental extractions by Kovarik, J.P., Voborna, I., Barclay, S., Iqbal, M.S., Cunnell, M., Kelly, C., Willis, N., Kennedy, M., Kovarik, J.

“…In head and neck cancer (HNC), osteoradionecrosis (ORN) is one of the most significant complications of radiotherapy (RT). With an absence of effective…”
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Commissioning of the new water line of the Central wastewater treatment plant in Prague and its impact on the operation of the existing water line by Wanner, J, Rosický, J, Kovařík, J, Srb, M, Lánský, M, Sýkora, P

“…Abstract This paper describes the commissioning of the new water line (NWL) of the Central wastewater treatment plant in Prague and also the gradual reduction…”
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Exposure to the COVID-19 pandemic environment and generosity by Brañas-Garza, P, Jorrat, D, Alfonso, A, Espín, A M, Muñoz, T García, Kovářík, J

“…We report data from an online experiment which allows us to study how generosity changed over a 6-day period during the initial explosive growth of the…”
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Comment on "Clinicopathological features and prognostic factors of salivary gland myoepithelial carcinoma: institutional experience of 42 cases" by Iqbal, M S, Patil, R, Kovarik, J, Jackson, M, Kelly, C

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Adaptive physiological water conservation explains hypertension and muscle catabolism in experimental chronic renal failure by Kovarik, Johannes J., Morisawa, Norihiko, Wild, Johannes, Marton, Adriana, Takase‐Minegishi, Kaoru, Minegishi, Shintaro, Daub, Steffen, Sands, Jeff M., Klein, Janet D., Bailey, James L., Kovalik, Jean‐Paul, Rauh, Manfred, Karbach, Susanne, Hilgers, Karl F., Luft, Friedrich, Nishiyama, Akira, Nakano, Daisuke, Kitada, Kento, Titze, Jens

“…Aim We have reported earlier that a high salt intake triggered an aestivation‐like natriuretic‐ureotelic body water conservation response that lowered muscle…”
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Efficacy and Safety of Vildagliptin in New‐Onset Diabetes After Kidney Transplantation—A Randomized, Double‐Blind, Placebo‐Controlled Trial by Haidinger, M., Werzowa, J., Hecking, M., Antlanger, M., Stemer, G., Pleiner, J., Kopecky, C., Kovarik, J. J., Döller, D., Pacini, G., Säemann, M. D.

“…New‐onset diabetes after transplantation (NODAT) is a serious complication after kidney transplantation, but therapeutic strategies remain underexplored…”
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Heart Failure with Preserved and Reduced Ejection Fraction in Hemodialysis Patients: Prevalence, Disease Prediction and Prognosis by Antlanger, Marlies, Aschauer, Stefan, Kopecky, Chantal, Hecking, Manfred, Kovarik, Johannes J., Werzowa, Johannes, Mascherbauer, Julia, Genser, Bernd, Säemann, Marcus D., Bonderman, Diana

“…Background/Aims: Heart failure (HF) is a main cause of mortality of hemodialysis (HD) patients. While HF with reduced ejection fraction (HFrEF) is known to…”
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Critical Role of Neprilysin in Kidney Angiotensin Metabolism by Kaltenecker, Christopher C., Domenig, Oliver, Kopecky, Chantal, Antlanger, Marlies, Poglitsch, Marko, Berlakovich, Gabriela, Kain, Renate, Stegbauer, Johannes, Rahman, Masudur, Hellinger, Roland, Gruber, Christian, Grobe, Nadja, Fajkovic, Harun, Eskandary, Farsad, Böhmig, Georg A., Säemann, Marcus D., Kovarik, Johannes J.

“…RATIONALE:Kidney homeostasis is critically determined by the coordinated activity of the renin-angiotensin system (RAS), including the balanced synthesis of…”
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Neprilysin is a Mediator of Alternative Renin-Angiotensin-System Activation in the Murine and Human Kidney by Domenig, Oliver, Manzel, Arndt, Grobe, Nadja, Königshausen, Eva, Kaltenecker, Christopher C., Kovarik, Johannes J., Stegbauer, Johannes, Gurley, Susan B., van Oyen, Dunja, Antlanger, Marlies, Bader, Michael, Motta-Santos, Daisy, Santos, Robson A., Elased, Khalid M., Säemann, Marcus D., Linker, Ralf A., Poglitsch, Marko

“…Cardiovascular and renal pathologies are frequently associated with an activated renin-angiotensin-system (RAS) and increased levels of its main effector and…”
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Assessment of Batch to Batch Variation in Polyclonal Antithymocyte Globulin Preparations by POPOW, Irene, LEITNER, Judith, MAJDIC, Otto, KOVARIK, Johannes J, SAEMANN, Marcus D, ZLABINGER, Gerhard J, STEINBERGER, Peter

“…Antithymocyte globulins (ATGs) are used to prevent and treat allograft rejection and graft versus host disease. They are purified IgG fractions derived from…”
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Role of Adjuvant Radiotherapy to the Neck in pN0 Carcinoma of the Oral Cavity by Iqbal, M.S., Kovarik, J., Kelly, C.

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Azithromycin suppresses CD4+ T-cell activation by direct modulation of mTOR activity by Ratzinger, F., Haslacher, H., Poeppl, W., Hoermann, G., Kovarik, J. J., Jutz, S., Steinberger, P., Burgmann, H., Pickl, W. F., Schmetterer, K. G.

“…Advanced macrolides, such as azithromycin (AZM) or clarithromycin (CLM), are antibiotics with immunomodulatory properties. Here we have sought to evaluate…”
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Role of Adjuvant Radiotherapy in Acinic Cell Carcinoma of the Salivary Glands: A Systematic Review by Patil, R., Uzzaman, L., Kelly, C., Kovarik, J., Jackson, M., Paterson, C., Munro, S.P., Wilson, A., Iqbal, M.S.

“…A systematic review was carried out to evaluate if adjuvant radiotherapy for acinic cell carcinomas (ACCs) of salivary glands improves survival. Twelve…”
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A multi-omics based anti-inflammatory immune signature characterizes long COVID-19 syndrome by Kovarik, Johannes J., Bileck, Andrea, Hagn, Gerhard, Meier-Menches, Samuel M., Frey, Tobias, Kaempf, Anna, Hollenstein, Marlene, Shoumariyeh, Tarik, Skos, Lukas, Reiter, Birgit, Gerner, Marlene C., Spannbauer, Andreas, Hasimbegovic, Ena, Schmidl, Doreen, Garhöfer, Gerhard, Gyöngyösi, Mariann, Schmetterer, Klaus G., Gerner, Christopher

“…To investigate long COVID-19 syndrome (LCS) pathophysiology, we performed an exploratory study with blood plasma derived from three groups: 1) healthy…”
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Is Chemotherapy with Carboplatin and 5-Fluorouracil Effective, Worthwhile Palliative Treatment in Recurrent/Metastatic Non-oral Cavity Head and Neck Carcinoma? by Iqbal, M.S., Gray, I., Jackson, M., Kovarik, J., Kelly, C.

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Extra-mandibular Osteoradionecrosis after the Treatment of Head and Neck Cancer by Kovarik, P.D.E., Patil, R., Cvek, J., Kelly, C., Jackson, M., Mackenzie, L., West, N., Willis, N., Kovarik, J.P., Banks, R., Kennedy, M., Adams, J., Iqbal, M.S.

“…Osteoradionecrosis (ORN) is a serious toxicity of head and neck radiotherapy. It predominantly affects the mandible. Extra-mandibular ORN is rare. The aim of…”
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Intrarenal Renin-Angiotensin-System Dysregulation after Kidney Transplantation by Kovarik, Johannes J., Kaltenecker, Christopher C., Kopecky, Chantal, Domenig, Oliver, Antlanger, Marlies, Werzowa, Johannes, Eskandary, Farsad, Kain, Renate, Poglitsch, Marko, Schmaldienst, Sabine, Böhmig, Georg A., Säemann, Marcus D.

“…Angiotensin-converting enzyme inhibitors (ACEis) are beneficial in patients with chronic kidney disease (CKD). Yet, their clinical effects after kidney…”
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Highly reduced binding to high and low affinity mouse Fc gamma receptors by L234A/L235A and N297A Fc mutations engineered into mouse IgG2a by Arduin, E., Arora, S., Bamert, P.R., Kuiper, T., Popp, S., Geisse, S., Grau, R., Calzascia, T., Zenke, G., Kovarik, J.

“…•Introduction of two silencing Fc mutations in a mouse IgG backbone.•LALA and N297 Fc mutation in mouse IgG2a reduce binding to mouse FcγRs.•LALA and N297 Fc…”
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Molecular regulation of the renin-angiotensin system in haemodialysis patients by Kovarik, Johannes J, Antlanger, Marlies, Domenig, Oliver, Kaltenecker, Christopher C, Hecking, Manfred, Haidinger, Michael, Werzowa, Johannes, Kopecky, Chantal, Säemann, Marcus D

“…Blockade of the renin-angiotensin system (RAS) exerts beneficial effects in patients with mild-to-moderate chronic kidney disease, yet evidence suggesting a…”
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A randomized controlled trial-based algorithm for insulin-pump therapy in hyperglycemic patients early after kidney transplantation by Werzowa, Johannes M, Säemann, Marcus D, Mohl, Alexander, Bergmann, Michael, Kaltenecker, Christopher C, Brozek, Wolfgang, Thomas, Andreas, Haidinger, Michael, Antlanger, Marlies, Kovarik, Johannes J, Kopecky, Chantal, Song, Peter X K, Budde, Klemens, Pascual, Julio, Hecking, Manfred

“…Treating hyperglycemia in previously non-diabetic individuals with exogenous insulin immediately after kidney transplantation reduced the odds of developing…”
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