Neuropsychological relationships in paranoid schizophrenia with and without delusional misidentification syndromes. A comparative study

Delusional misidentification syndromes (DMSs) and schizophrenia are strongly associated, since the former occur predominantly in the context of paranoid schizophrenia. However, the possible underlying neuropsychological relationships between DMSs and paranoid schizophrenia have not been thoroughly i...

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Bibliographic Details
Published in:	Progress in neuro-psychopharmacology & biological psychiatry Vol. 32; no. 6; pp. 1445 - 1448
Main Authors:	Lykouras, L., Typaldou, M., Mourtzouchou, P., Oulis, P., Koutsaftis, C., Dokianaki, F., Michalopoulou, P.G., Havaki-Kontaxaki, M., Christodoulou, C.
Format:	Journal Article
Language:	English
Published:	Amsterdam Elsevier Inc 01-08-2008 Elsevier
Subjects:	Adult Adult and adolescent clinical studies Biological and medical sciences Delusional misidentification syndromes Delusions - complications Delusions - psychology Female Functional Laterality Humans Male Medical sciences Neuropharmacology Neuropsychological study Neuropsychological Tests Paranoid schizophrenia Pharmacology. Drug treatments Psychology. Psychoanalysis. Psychiatry Psychomotor Performance - physiology Psychopathology. Psychiatry Psychoses Schizophrenia Schizophrenia, Paranoid - complications Schizophrenia, Paranoid - psychology Schizophrenic Psychology Wechsler Scales Delusional misidentification syndromes DMSs Neuropsychological study Paranoid schizophrenia Psychosis Delusional misidentification syndrome Comparative study
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Summary:	Delusional misidentification syndromes (DMSs) and schizophrenia are strongly associated, since the former occur predominantly in the context of paranoid schizophrenia. However, the possible underlying neuropsychological relationships between DMSs and paranoid schizophrenia have not been thoroughly investigated. The aim of the present study was to investigate whether DMSs in paranoid schizophrenia are associated with a distinct neuropsychological substrate indicative of differential bilateral frontal and right hemisphere dysfunction. We compared two matched groups of paranoid schizophrenic patients with ( N = 22) and without ( N = 22) DMS(s) on a battery of neuropsychological tests assessing mainly frontal and right hemisphere functions. No statistically significant differences were detected between the two groups. Our findings are indicative of a bilateral frontal and right hemisphere dysfunction of equal severity in both DMS and non-DMS patients with paranoid schizophrenia.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0278-5846 1878-4216
DOI:	10.1016/j.pnpbp.2008.04.012