Search Results - "Koury, Luisa C."

Combining gene mutation with gene expression analysis improves outcome prediction in acute promyelocytic leukemia by Lucena-Araujo, Antonio R., Coelho-Silva, Juan L., Pereira-Martins, Diego A., Silveira, Douglas R., Koury, Luisa C., Melo, Raul A.M., Bittencourt, Rosane, Pagnano, Katia, Pasquini, Ricardo, Nunes, Elenaide C., Fagundes, Evandro M., Gloria, Ana B., Kerbauy, Fábio, de Lourdes Chauffaille, Maria, Bendit, Israel, Rocha, Vanderson, Keating, Armand, Tallman, Martin S., Ribeiro, Raul C., Dillon, Richard, Ganser, Arnold, Löwenberg, Bob, Valk, P.J.M., Lo-Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Rego, Eduardo M.

“…By combining the analysis of mutations with aberrant expression of genes previously related to poorer prognosis in both acute promyelocytic leukemia (APL) and…”
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Clinical significance of mitochondrial DNA content in acute promyelocytic leukaemia by Pereira‐Martins, Diego A., Coelho‐Silva, Juan L., Weinhäuser, Isabel, Franca‐Neto, Pedro L., Silveira, Douglas R., Ortiz, César, Moreira‐Aguiar, Amanda, Lima, Marinus M., Koury, Luisa C., Melo, Raul A., Glória, Ana B., Fagundes, Evandro M., Lino, Bruno K., Pagnano, Katia, Bittencourt, Rosane, Nunes, Elenaide, Traina, Fabiola, Figueiredo‐Pontes, Lorena, Keating, Armand, Tallman, Martin S., Ribeiro, Raul C., Dilon, Richard, Ganser, Arnold, Sanz, Miguel A., Berliner, Nancy, Valk, Peter, Löwenberg, Bob, Ottone, Tiziana, Noguera, Nelida I., Voso, Maria T., Paoloni, Francesca, Fazi, Paola, Ammatuna, Emanuele, Huls, Gerwin, Schuringa, Jan Jacob, Rego, Eduardo M., Lucena‐Araujo, Antonio R.

“…Summary Although a growing body of evidence demonstrates that altered mtDNA content (mtDNAc) has clinical implications in several types of solid tumours, its…”
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STMN1 is highly expressed and contributes to clonogenicity in acute promyelocytic leukemia cells by Vicari, Hugo Passos, Coelho-Silva, Juan Luiz, Pereira-Martins, Diego A., Lucena-Araujo, Antônio Roberto, Lima, Keli, Lipreri da Silva, Jean Carlos, Scheucher, Priscila Santos, Koury, Luisa C., de Melo, Raul A., Bittencourt, Rosane, Pagnano, Katia, Nunes, Elenaide, Fagundes, Evandro M., Kerbauy, Fabio, de Figueiredo-Pontes, Lorena Lobo, Costa-Lotufo, Leticia Veras, Rego, Eduardo Magalhães, Traina, Fabiola, Machado-Neto, João Agostinho

“…Summary Stathmin 1 (STMN1) is a microtubule-destabilizing protein highly expressed in hematological malignancies and involved in proliferation and…”
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NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia by Thomé, Carolina Hassibe, Ferreira, Germano Aguiar, Pereira-Martins, Diego Antonio, dos Santos, Guilherme Augusto, Ortiz, César Alexander, de Souza, Lucas Eduardo Botelho, Sobral, Lays Martins, Silva, Cleide Lúcia Araújo, Scheucher, Priscila Santos, Gil, Cristiane Damas, Leopoldino, Andréia Machado, Silveira, Douglas R. A., Coelho-Silva, Juan L., Traina, Fabíola, Koury, Luisa C., Melo, Raul A. M., Bittencourt, Rosane, Pagnano, Katia, Pasquini, Ricardo, Nunes, Elenaide C., Fagundes, Evandro M., Gloria, Ana Beatriz F., Kerbauy, Fábio Rodrigues, Chauffaille, Maria de Lourdes, Keating, Armand, Tallman, Martin S., Ribeiro, Raul C., Dillon, Richard, Ganser, Arnold, Löwenberg, Bob, Valk, Peter, Lo-Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Faça, Vitor Marcel, Rego, Eduardo M.

“…Non-T cell activation linker (NTAL) is a lipid raft-membrane protein expressed by normal and leukemic cells and involved in cell signaling. In acute…”
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Reduced SLIT2 is Associated with Increased Cell Proliferation and Arsenic Trioxide Resistance in Acute Promyelocytic Leukemia by Weinhäuser, Isabel, Pereira-Martins, Diego A., Ortiz, Cesar, Silveira, Douglas R., Simões, Luíse A. A., Bianco, Thiago M., Araujo, Cleide L., Koury, Luisa C., Melo, Raul A. M., Bittencourt, Rosane I., Pagnano, Katia, Pasquini, Ricardo, Nunes, Elenaide C., Fagundes, Evandro M., Gloria, Ana B., Kerbauy, Fábio, Chauffaille, Maria de Lourdes, Keating, Armand, Tallman, Martin S., Ribeiro, Raul C., Dillon, Richard, Ganser, Arnold, Löwenberg, Bob, Valk, Peter, Lo-Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Ammatuna, Emanuele, Lucena-Araujo, Antonio R., Schuringa, Jan Jacob, Rego, Eduardo M.

“…The SLIT-ROBO axis plays an important role in normal stem-cell biology, with possible repercussions on cancer stem cell emergence. Although the Promyelocytic…”
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Clinical impact of BAALC expression in high-risk acute promyelocytic leukemia by Lucena-Araujo, Antonio R., Pereira-Martins, Diego A., Koury, Luisa C., Franca-Neto, Pedro L., Coelho-Silva, Juan L., de Deus Wagatsuma, Virginia M., Melo, Raul A.M., Bittencourt, Rosane, Pagnano, Katia, Pasquini, Ricardo, Chiattone, Carlos S., Fagundes, Evandro M., Chauffaille, Maria de Lourdes, Schrier, Stanley L., Tallman, Martin S., Ribeiro, Raul C., Grimwade, David, Ganser, Arnold, Löwenberg, Bob, Lo-Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Rego, Eduardo M.

“…Although overexpression of the brain and acute leukemia, cytoplasmic (BAALC) gene is associated with primary resistant disease and shorter relapse-free,…”
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Clinical Significance of Mitochondrial DNA Content in Acute Promyelocytic Leukemia by Lucena-Araujo, Antonio R., Pereira-Martins, Diego A, Coelho-Silva, Juan L, Weinhäuser, Isabel, Franca-Neto, Pedro Luis, Silveira, Douglas RA, Lima, Marinus M, Schuringa, Jan Jacob, Koury, Luisa C, Melo, Raul Antônio Morais, Bittencourt, Rosane, Pagnano, Katia B, Nunes, Elenaide C., Fagundes, Evandro Maranhão, Kerbauy, Fabio R., Figueredo-Pontes, Lorena, Rego, Eduardo M

“…Used in the clinical practice for more than three decades, the all-trans retinoic acid (ATRA) rendered acute promyelocytic leukemia (APL) the most curable…”
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Arsenic Trioxide Abrogate MN1 Mediated RA-Resistance in Acute Promyelocytic Leukemia by Pereira-Martins, Diego A, Coelho-Silva, Juan L, Weinhäuser, Isabel, Koury, Luisa C A, Melo, Raul Antônio Morais, Bittencourt, Rosane, Pagnano, Katia B, Pasquini, Ricardo, Nunes, Elenaide C., Fagundes, Evandro Maranhão, Gloria, Ana Beatriz F., Kerbauy, Fabio R., Keating, Armand, Tallman, Martin S., Ribeiro, Raul, Dillon, Richard, Ganser, Arnold, Heuser, Michael, Löwenberg, Bob, Valk, Peter, Sanz, Miguel A., Berliner, Nancy, Lucena-Araujo, Antonio R., Rego, Eduardo M

“…Introduction: Described as a well know marker of worse prognosis in acute myeloid leukemia (AML), MN1 overexpression has been associated with inv(16) or EVI1…”
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Clinical and Functional Studies Reveal That TP73 Isoforms Levels Are Associated with Prognosis and RA-Resistance in Acute Promyelocytic Leukemia by Ortiz Rojas, César Alexander, Pereira-Martins, Diego A, Weinhäuser, Isabel, Almeida, Luciana Yamamoto, Bianco, Thiago Mantello, Figueiredo-Pontes, Lorena Lobo, Koury, Luisa C A, Melo, Raul Antônio Morais, Bittencourt, Rosane, Pagnano, Katia B, Pasquini, Ricardo, Nunes, Elenaide C., Fagundes, Evandro Maranhão, Gloria, Ana Beatriz F., Kerbauy, Fabio R., Keating, Armand, Tallman, Martin S., Ribeiro, Raul, Dillon, Richard, Ganser, Arnold, Löwenberg, Bob, Valk, Peter, Sanz, Miguel A., Berliner, Nancy, Rego, Eduardo M

“…Background: TP73 isoforms gained particular relevance in acute promyelocytic leukemia (APL) since Bernasola et al (JEM. 2004) demonstrated that TAp73 was…”
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Slit-Robo Pathway Is Clinically Relevant and May Represent a Potential Target in Acute Promyelocytic Leukemia by Weinhäuser, Isabel, Pereira-Martins, Diego Antonio, Ortiz, Cesar, Schiavinato, Josiane Lilian, Bonaldo, Camila, Koury, Luisa C, De Deus Wagatsuma, Virginia Mara, Melo, Raul Antônio Morais, Bittencourt, Rosane, Pagnano, Katia B, Fagundes, Evandro Maranhão, Gloria, Ana Beatriz F., Kerbauy, Fabio R., Chauffaille, Maria de Lourdes, Pasquini, Ricardo, Tallman, Martin S., Ribeiro, Raul, Dillon, Richard, Keating, Armand, Ganser, Arnold, Lowenberg, Bob, Valk, Peter, Lo-Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Lucena-Araujo, Antonio R., Rego, Eduardo Magalhães

“…Background: The Slit-Robo pathway has been shown to participate in the pathogenesis of several malignant diseases in addition to its physiologic role during…”
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Abstract A39: Nuclear SET domain (NSD) protein lysine methyltransferases (KMT) are higher expressed in acute myeloid leukemia by Wagatsuma, Virginia Mara de Deus, Koury, Luisa C. A., Sánchez, Silvia Helena, Figueiredo-Pontes, Lorena Lobo, Silva, Fernanda Borges da, Dore, Adriana Ines, Lima, Ana Silvia Gouvea de, Lucena-Araujo, Antonio Roberto, Traina, Fabiola, Saldanha-Araujo, Felipe, Pittella, Fabio, Rego, Eduardo Magalhães

“…Abstract The nuclear SET domain (NSD) protein lysine methyltransferases (KMT) family is composed of three members, NSD1/KMT3B, NSD2/WHSC1/MMSET, and…”
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Combining Gene Mutation with Gene Expression Data Improves Outcomes Prediction in Acute Promyelocytic Leukemia by Lucena-Araujo, Antonio R., Pereira-Martins, Diego A, Koury, Luisa C A, Coelho-Silva, Juan Luiz, Melo, Raul Antônio Morais, Bittencourt, Rosane, Pagnano, Katia B, Pasquini, Ricardo, Chiattone, Carlos, Fagundes, Evandro Maranhão, Chauffaille, Maria de Lourdes, Schrier, Stanley L., Tallman, Martin S., Ribeiro, Raul C., Grimwade, David, Ganser, Arnold, Lowenberg, Bob, Lo Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Rego, Eduardo Magalhães

“…In the context of all-trans retinoic acid (ATRA) and anthracycline-based chemotherapy, heterogeneity of clinical outcomes of patients with acute promyelocytic…”
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Metformintreatment Overcomes ATRA-Resistance in Acute Promyelocytic Leukemia and Increases FOXO3A Expression by Pereira-Martins, Diego Antonio, Ortiz, Cesar, Franca-Neto, Pedro Luis, Weinhäuser, Isabel, Schiavinato, Josiane Lilian, Palma, Patrícia Vianna Bonini, Bonaldo, Camila, Koury, Luisa C A, Do Nascimento, Mariane Cristina, Melo, Raul Antônio Morais, Bittencourt, Rosane, Pagnano, Katia B B, Pasquini, Ricardo, Fagundes, Evandro Maranhão, Gloria, Ana Beatriz F., Kerbauy, Fabio R., Chauffaille, Maria de Lourdes, Keating, Armand, Tallman, Martin S., Ribeiro, Raul, Dillon, Richard, Ganser, Arnold, Lowenberg, Bob, Valk, Peter, Lo-Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Lucena-Araujo, Antonio R., Rego, Eduardo Magalhães

“…Introduction:FOXO3A is a transcription factor shown to be involved in all-trans retinoic acid (ATRA)-induced granulocytic differentiation and apoptosis in…”
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Association between Nuclear SET Domain (NSD) Protein Lysine Methyltransferases (KMT) Expression and Poor Prognosis in Acute Promyelocytic Leukemia (APL) Patients Treated with ATRA and Anthracycline Protocol by De Deus Wagatsuma, Virginia Mara, Pereira-Martins, Diego A, Sánchez Mendoza, Silvia Elena, Koury, Luisa C A, Nascimento, Mariane Cristina, Melo, Raul Antônio Morais, Bittencourt, Rosane, Pagnano, Katia B, Pasquini, Ricardo, Chiattone, Carlos, Fagundes, Evandro Maranhão, Chauffaille, Maria de Lourdes, Lucena-Araujo, Antonio R., Tallman, Martin S., Schrier, Stanley L., Ribeiro, Raul C., Ganser, Arnold, Lowenberg, Bob, Lo Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Rego, Eduardo Magalhães

“…Introduction: In the last decades, it has been described the potential role of Nuclear SET domain (NSD) Protein Lysine Methyltransferases (KMT) family members…”
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The Use of Cyclosporine in Association with Chemotherapy As Induction Treatment in Patients with Acute Myeloid Leukemia (AML) and High Rhodamine Efflux at Diagnosis Results in Higher Complete Hematological Remission Rates, but Does Not Prolong Overall Survival by Koury, Luisa C A, Figueiredo-Pontes, Lorena Lobo, Simoes, Belinda Pinto, Oliveira, Luciana C O, Dalmazzo, Leandro F F, Pintão, Maria Carolina Tostes, Garcia, Aglair B, Falcão, Roberto Passetto, Rego, Eduardo Magalhães

“…The overexpression of P-glycoprotein (Pgp) in leukemic blasts of Acute Myeloid Leukemia (AML) is associated with lower complete remission (CR) rates and…”
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Nuclear SET Domain (NSD) Protein Lysine Methyltransferases (KMT) Family Members Expression in Acute Myeloid Leukemia by De Deus Wagatsuma, Virginia Mara, Koury, Luisa C A, Sánchez, Silvia Elena, Pontes, Lorena Lobo Figueiredo, da Silva, Fernanda Borges, Dore, Adriana Ines, Gouvêa de Lima, Ana Silvia, Lucena-Araujo, Antonio R., Almeida, Luciana Yamamoto, Traina, Fabiola, Saldanha-Araújo, Felipe, Pittella-Silva, Fabio, Rego, Eduardo Magalhães

“…The Nuclear SET Domain (NSD) Protein Lysine Methyltransferases (KMT) family is composed of three members: NSD1/KMT3B, NSD2/WHSC1/MMSET and NSD3/WHSC1L1 which…”
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