Search Results - "Kounta, Mame Bou"
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Modulation of in vitro antimalarial responses by polymorphisms in Plasmodium falciparum ABC transporters (pfmdr1 and pfmdr5)
Published in Acta tropica (01-08-2019)“…[Display omitted] •Two ATP-binding cassette transporter genes (pfmdr1 and pfmdr5) sequenced in 67 P. falciparum isolates from Dakar, Senegal.•Fourteen…”
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Confirmation of Plasmodium falciparum in vitro resistance to monodesethylamodiaquine and chloroquine in Dakar, Senegal, in 2015
Published in Malaria journal (16-03-2017)“…In response to increasing resistance to anti-malarial drugs, Senegal adopted artemisinin-based combination therapy (ACT) as the first-line treatment for…”
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Absence of association between polymorphisms in the K13 gene and the presence of Plasmodium falciparum parasites at day 3 after treatment with artemisinin derivatives in Senegal
Published in International journal of antimicrobial agents (01-06-2017)“…Highlights • The K13-propeller gene of 181 isolates from Senegalese patients collected in 2015–2016 was sequenced. • Nine of 119 patients treated with…”
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Baseline Ex Vivo and Molecular Responses of Plasmodium falciparum Isolates to Piperaquine before Implementation of Dihydroartemisinin-Piperaquine in Senegal
Published in Antimicrobial agents and chemotherapy (01-05-2019)“…Dihydroartemisinin-piperaquine, which was registered in 2017 in Senegal, is not currently used as the first-line treatment against uncomplicated malaria. A…”
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Association between Polymorphisms in the Pfmdr6 Gene and Ex Vivo Susceptibility to Quinine in Plasmodium falciparum Parasites from Dakar, Senegal
Published in Antimicrobial agents and chemotherapy (01-03-2017)“…Polymorphisms and the overexpression of transporter genes, especially of the ATP-binding cassette superfamily, have been involved in antimalarial drug…”
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Association between Polymorphisms in the Pf mdr6 Gene and Ex Vivo Susceptibility to Quinine in Plasmodium falciparum Parasites from Dakar, Senegal
Published in Antimicrobial agents and chemotherapy (01-03-2017)“…Polymorphisms and the overexpression of transporter genes, especially of the ATP-binding cassette superfamily, have been involved in antimalarial drug…”
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Ex vivo activity of Proveblue, a methylene blue, against field isolates of Plasmodium falciparum in Dakar, Senegal from 2013–2015
Published in International journal of antimicrobial agents (01-08-2017)“…•Proveblue, a methylene blue preparation, was highly active against Plasmodium falciparum isolates (8.1 nM).•Proveblue was more active than standard…”
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