Search Results - "Koukiali, Anastasia"
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Nuclear Translocation of SRPKs Is Associated with 5-FU and Cisplatin Sensitivity in HeLa and T24 Cells
Published in Cells (Basel, Switzerland) (30-03-2021)“…Serine/arginine protein kinases (SRPKs) phosphorylate Arg/Ser dipeptide-containing proteins that play crucial roles in a broad spectrum of basic cellular…”
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Synthesis and Anti-Angiogenic Activity of Novel c(RGDyK) Peptide-Based JH-VII-139-1 Conjugates
Published in Pharmaceutics (22-01-2023)“…Peptide-drug conjugates are delivery systems for selective delivery of cytotoxic agents to target cancer cells. In this work, the optimized synthesis of…”
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SR Protein Kinase 1 Inhibition by TAF15
Published in Cells (Basel, Switzerland) (01-01-2023)“…Although SRPKs were discovered nearly 30 years ago, our understanding of their mode of regulation is still limited. Regarded as constitutively active enzymes…”
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Synthesis and Biological Evaluation of a c(RGDyK) Peptide Conjugate of SRPIN803
Published in ACS omega (26-10-2021)“…In the present study, SRPIN803 and c(RGDyK)-SRPIN803 hybrid compounds were efficiently synthesized and evaluated for their stability in human plasma and…”
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PIM-1L Kinase Binds to and Inactivates SRPK1: A Biochemical and Molecular Dynamics Study
Published in Proteins, structure, function, and bioinformatics (27-10-2024)“…SR/RS dipeptide repeats vary in both length and position, and are phosphorylated by SR protein kinases (SRPKs). PIM-1L, the long isoform of PIM-1 kinase, the…”
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