Search Results - "Kouji, Morikawa"

Binding and functional characterization of α1-adrenoceptor subtypes in the rat prostate by HIRAOKA, Y, OHMURA, T, OSHITA, M, WATANABE, Y, MORIKAWA, K, NAGATA, O, KATO, H, TANIGUCHI, T, MURAMATSU, I

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Potent inhibition of spontaneous rhythmic contraction by a novel β2-adrenoceptor agonist, HSR-81, in pregnant rat uterus by Ohashi, Tetsuo, Hashimoto, Shigeki, Morikawa, Kouji, Kato, Hideo, Ito, Yasuo, Asano, Masahisa, Azuma, Hiroshi

“…We examined the effect of HSR-81 ((−)-( R)-α-[( tert-butylamino)methyl]-2-chloro-4-hydroxybenzyl alcohol l-tartrate), a newly developed, potent and selective β…”
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Laxative and Anti-diarrheal Activity of Polycarbophil in Mice and Rats by Saito, Takaharu, Mizutani, Fujie, Iwanaga, Yuji, Morikawa, Kouji, Kato, Hideo

“…We investigated the laxative and anti-diarrheal activity of polycarbophil, an insoluble hydro-philic polymer, in comparison with other agents used for treating…”
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Characterization of Acetylcholinesterase-Inhibition by Itopride by Iwanaga, Yuji, Kimura, Tatsuya, Miyashita, Naoshi, Morikawa, Kouji, Nagata, Osamu, Itoh, Zen, Kondo, Yoichi

“…Itopride is a gastroprokinetic benzamide derivative. This agent inhibited both electric eel acetylcholinesterase (AChE) and horse serum butyrylcholinesterase…”
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Calcium Polycarbophil, a Water Absorbing Polymer, Increases Bowel Movement and Prevents Sennoside-Induced Diarrhea in Dogs by Saito, Takaharu, Yamada, Takehisa, Iwanaga, Yuji, Morikawa, Kouji, Nagata, Osamu, Kato, Hideo, Mizumoto, Akiyoshi, Itoh, Zen

“…The effects of calcium polycarbophil(CP), a water−absorbing polymer, on bowel movement were examined in comparison with known laxatives and anti−diarrheal…”
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The Effect of Tulobuterol Tape on Histamine-Induced Bronchoconstriction in Conscious Guinea Pigs: Long Duration of Action by Keiichi, Musoh, Kayoko, Kawamura, Isao, Miyake, Shino, Shimada, Tetsuo, Ohashi, Yuji, Iwanaga, Kouji, Morikawa, Hideo, Kato

“…The objective of the present study was to determine the action duration of tulobuterol tape within a 24-hr period in conscious guinea pigs. The…”
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Effect of novel colonic prokinetic agents, AU-130 and AU-224, on intestinal motility and defecation in rats and dogs by Saito, Takaharu, Tubouchi, Tadashi, Mizutani, Fujie, Iwanaga, Yuji, Morikawa, Kouji, Nagata, Osamu, Kato, Hideo

“…Gastrointestinal prokinetic actions of AU-130, [4-(4-amino-5 -chloro-2-methoxybenzamido) piperidino] acetic acid, and its ester type prodrug AU-224 were…”
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Studies on the Novel Antiallergic Agent HSR-609: Its Penetration into the Central Nervous System in Mice and Guinea Pigs and Its Selectivity for the Histamine H1-Receptor by Kakiuchi, Masato, Ohashi, Tetsuo, Musoh, Keiichi, Kawamura, Kimio, Morikawa, Kouji, Kato, Hideo

“…We studied the pharmacological characteristics of HSR-609 (3-[4-(8-fluoro-5, 11-dihydrobenz[b]oxepino[4, 3-b]pyridin-11-ylidene)-piperidino]propionic acid…”
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Characterization of the endothelin receptor subtypes in human prostate by Oshita, Masafumi, Hiraoka, Yasuko, Morikawa, Kouji, Nagata, Osamu, Hahn, Klaus J., Okada, Kenichiro, Taniguchi, Takanobu, Muramatsu, Ikunobu

“…Endothelin receptor subtypes in human prostate from BPH patients were investigated in binding and functional studies. In receptor binding experiments, LU135252…”
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Protective effect by anti-spasmodic activity of tiquizium bromide on NSAIDs-induced gastric injury in rats by Tokunaga, Hirotaka, Yamauchi, Toshie, Mizutani, Fujie, Saito, Takaharu, Iwanaga, Yuji, Morikawa, Kouji, Nagata, Osamu, Kato, Hideo

“…NSAIDs produce gastric injury by the results of PGs deficiency and acid secretion. On the other hand, gastric hypercontraction mediated by cholinergic neurons…”
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Stimulatory Effects of HSR-803 on Ileal Motor Activity by Iwanaga, Yuji, Suzuki, Nagao, Kato, Ken-ichi, Kimura, Tatsuya, Morikawa, Kouji, Kato, Hideo, Ito, Yasuo, Gomi, Yasuo

“…Stimulatory effects of HSR-803 on intestinal motor activity in vitro were studied in guinea pig ileum. HSR-803 (1×10-6-1×10-4M) increased the amplitude of…”
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Pharmacological characterization of HSR-609, a novel amphoteric antiallergic agent by Hiraoka, Yasuko, Oshita, Masafumi, Hosotani, Takeo, Watanabe, Yoshmari, Musoh, Keiichi, Ohashi, Tetsuo, Morikawa, Kouji, Nagata, Osamu, Kato, Hideo

“…Pharmacological profile of a novel selective histamine H_1 receptor antagonist, HSR-609 (3-[4-(8-fluoro-5,11dihydrobenz[b]oxepino[4,3-b]pyridin-…”
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Cytoprotective activity of tiquizium bromide (HSR-902) and its mechanism by Morikawa, K, Aratani, T, Mizutani, F, Kato, H, Ito, Y

“…The effects of HSR-902, an antimuscarinic agent, on acute gastric mucosal lesions induced by various necrotizing agents, gastric mucus secretion and gastric…”
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Potent inhibition of spontaneous rhythmic contraction by a novel β2-adrenoceptor agonist, HSR-81, in pregnant rat uterus by Ohashi, Tetsuo, Hashimoto, Shigeki, Morikawa, Kouji, Kato, Hideo, Ito, Yasuo, Azuma, Hiroshi, Asano, Masahisa

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Pharmacological Studies on the Selectivity of HV-723, a New Alpha-1 Adrenoceptor Antagonist by OSHITA, Masafumi, IWANAGA, Yuji, HASHIMOTO, Shigeki, MORIKAWA, Kouji, MURAMATSU, Ikunobu

“…The pharmacological profile of a new aipha-1 adrenoceptor antagonist, α-ethyl - 3,4,5 - trimethoxy - α - (3 - ((2 - (2 - methoxyphenoxy) ethyl) amino)propyl)…”
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Effects of (+/-)-4'-ethyl-2-methyl-3-(l-pyrrolidinyl) propiophenone hydrochloride (HY-770) on the bladder function by Morikawa, K, Kakiuchi, M, Yamauchi, T, Hashimoto, S, Miyashita, N, Ichihashi, M, Sawada, Y, Kato, H, Ito, Y

“…The effects of HY-770 on micturition reflexes in rats, dogs and cats and urethral pressure in dogs were compared with those of flavoxate.HC1 (flavoxate),…”
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Change in bladder contractility associated with bladder overactivity in rats with cerebral infarction by Yokoyama, O, Komatsu, K, Ishiura, Y, Nakamura, Y, Morikawa, K, Namiki, M

“…To evaluate the contractile properties of overactive bladder from rats in the chronic stage of experimental cerebral infarction. Cystometry was performed in…”
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In Vitro Pharmacological Profile of the Novel .ALPHA.1-Adrenoceptor Antagonist HSR-175 by Hashimoto, Shigeki, Oshita, Masafumi, Morikawa, Kouji, Kato, Hideo, Ito, Yasuo, Kigoshi, Shigeru, Muramatsu, Ikunobu

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Stimulatory effects of HSR-803 on the ileal peristalsis by Iwanaga, Yuji, Suzuki, Nagao, Kato, Ken-ichi, Kimura, Tatsuya, Morikawa, Kouji, Gomi, Yasuo

“…Effects of HSR-803, a new gastroprokinetic agent, on the motor activity of the isolated guinea pig ileum were studied. HSR-803 (10^-6 -10^-4 M) increased the…”
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Pharmacological Studies on the Novel Antiallergic Agent HSR-609: Its Effects on Behavior in Mice and Electroencephalograms in Rabbits by Kakiuchi, Masato, Ohashi, Tetsuo, Tanaka, Kazuo, Kamiyama, Kazuko, Morikawa, Kouji, Kato, Hideo

“…We studied the central nervous system (CNS) effects of HSR-609 (3-[4-(8-fluoro-5, 11-dihydrobenz[b]oxepino[4, 3-b]pyridin-11-ylidene)piperidino]propionic acid…”
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