Search Results - "Kouhi, Aida"
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1
Brain Disposition of Antibody-Based Therapeutics: Dogma, Approaches and Perspectives
Published in International journal of molecular sciences (16-06-2021)“…Due to their high specificity, monoclonal antibodies have been widely investigated for their application in drug delivery to the central nervous system (CNS)…”
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2
Survival rate of ovarian cancer in Asian countries: a systematic review and meta-analysis
Published in BMC cancer (16-06-2023)“…Ovarian cancer is amongst one of the most commonly occurring cancers affecting women, and the leading cause of gynecologic related cancer death. Its poor…”
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3
Survival rate of cervical cancer in Asian countries: a systematic review and meta-analysis
Published in BMC women's health (14-12-2023)“…Cancer is one of the main causes of death, and cervical cancer is the fourth most common cancer and the fourth leading cause of death from malignancy among…”
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4
[18F]-2′ -Fluoro-5-methyl-1-beta-D-arabinofuranosyluracil (18F-FMAU) in Prostate Cancer: Initial Preclinical Observations
Published in Molecular imaging (01-09-2012)“…We hypothesized that imaging-based assessment of cellular proliferation in prostate cancer may improve tumor characterization. We therefore evaluated the…”
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5
A Humanized Lym-1 CAR with Novel DAP10/DAP12 Signaling Domains Demonstrates Reduced Tonic Signaling and Increased Antitumor Activity in B-Cell Lymphoma Models
Published in Clinical cancer research (15-07-2020)“…The murine Lym-1 mAb targets a discontinuous epitope (Lym-1 epitope) on several subtypes of HLA-DR, which is upregulated in a majority of human B-cell…”
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6
Enhancing brain entry and therapeutic activity of chimeric antigen receptor T cells with intra-arterial NEO100 in a mouse model of CNS lymphoma
Published in Journal of neurosurgery (01-06-2024)“…Malignancies of the CNS are difficult to treat because the blood-brain barrier (BBB) prevents most therapeutics from reaching the intracranial lesions at…”
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7
Generation of a Monoclonal Antibody to Detect Elastin-like Polypeptides
Published in Biomacromolecules (12-08-2019)“…The identification and use of antibodies dominate the biologic, clinical diagnostic, and therapeutic landscapes. In particular, antibodies have become…”
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Elastin‐like polypeptide switches: A design strategy to detect multimeric proteins
Published in Protein science (01-09-2017)“…Elastin‐Like Polypeptides (ELPs) reversibly phase separate in response to changes in temperature, pressure, concentration, pH, and ionic species. While…”
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Characterization of Human Thymidine Kinase 2 Activity
Published 01-01-2014“…Although radiolabeled TdR has been used in vitro for measurement of rates of DNA synthesis, rapid in vivo catabolism has limited its utility as a radiotracer…”
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Dissertation