Search Results - "Koufaki, M."
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Multifunctional lipoic acid conjugates
Published in Current medicinal chemistry (2009)“…Several hundreds of studies published the last decade have reported that alpha-lipoic acid (LA) possess the potential to intervene in various therapeutically…”
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Alternative pharmacological interventions that limit myocardial infarction
Published in Current medicinal chemistry (01-12-2008)“…Despite current optimal treatment, the morbidity and mortality of coronary heart disease remain significant worldwide and open the way for the development of…”
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Surface composition and electronic properties of indium tin oxide and oxynitride films
Published in Surface science (15-09-2007)“…The surface properties of indium tin oxynitride films prepared by rf-sputtering in nitrogen atmosphere were investigated by X-ray and ultraviolet photoelectron…”
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Optical emission spectroscopy during fabrication of indium-tin-oxynitride films by RF-sputtering
Published in Applied surface science (31-10-2006)“…Indium-tin-oxide (ITO) and indium-tin-oxynitride (ITON) films have been deposited on glass by rf-sputtering from an ITO target, using Ar plasma and N 2 plasma,…”
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Novel Potent Inhibitors of Lipid Peroxidation with Protective Effects against Reperfusion Arrhythmias
Published in Journal of medicinal chemistry (22-11-2001)“…A series of new compounds that contain lipoic acid and trolox connected through spacers were synthesized and examined for their antioxidant activity and their…”
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1254 Topical corticosteroids stimulate T cell-dependent melanoma growth control
Published in Journal of investigative dermatology (01-05-2023)Get full text
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Ether Phospholipid-AZT Conjugates Possessing Anti-HIV and Antitumor Cell Activity. Synthesis, Conformational Analysis, and Study of Their Thermal Effects on Membrane Bilayers
Published in Journal of medicinal chemistry (24-05-2001)“…The 1-O-hexadecyl-2-O-methyl-sn-glyceryl phosphodiester AZT 4 and hexadecyl-phosphodiester AZT 5 derivatives were synthesized and found to be active against…”
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Design and Synthesis of Novel Quinolinone-3-aminoamides and Their α-Lipoic Acid Adducts as Antioxidant and Anti-inflammatory Agents
Published in Journal of medicinal chemistry (17-05-2007)“…A series of N-substituted-quinolinone-3-aminoamides and their hybrids containing the α-lipoic acid functionality were designed and synthesized as potential…”
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The conformational properties of the antineoplastic ether lipid 1-thiohexadecyl-2- O-methyl- S-glycero-3-phosphocholine
Published in Chemistry and physics of lipids (01-11-1996)“…Thio analogs of platelet activating factor (PAF) are of great interest because they exhibit antineoplastic properties both in vitro and in vivo. In contrast to…”
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Chroman/Catechol Hybrids: Synthesis and Evaluation of Their Activity against Oxidative Stress Induced Cellular Damage
Published in Journal of medicinal chemistry (12-01-2006)“…Three series of chromans substituted at positions 2 or 5 by catechol derivatives were synthesized, and their activity against oxidative stress induced cellular…”
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Synthesis of (Z)-4-hydroxytamoxifen and (Z)-2-[4-[1-(p-hydroxyphenyl)-2-phenyl]-1-butenyl]phenoxyacetic acid
Published in Journal of organic chemistry (28-06-2002)Get full text
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Synthesis of chroman analogues of lipoic acid and evaluation of their activity against reperfusion arrhythmias
Published in Bioorganic & medicinal chemistry (15-09-2004)“…[Display omitted] Novel hybrids of lipoic acid and trolox connected through triamine spacers as well as analogues in which the lipoic acid was attached at…”
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Bifunctional agents for reperfusion arrhythmias: Novel hybrid vitamin E/class I antiarrhythmics
Published in Bioorganic & medicinal chemistry (17-11-2003)“…We have synthesized a series of hybrid compounds combining the pharmacophoric redox moieties of vitamin E and key features responsible for the antiarrhythmic…”
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Antileishmanial Ring-Substituted Ether Phospholipids
Published in Journal of medicinal chemistry (27-02-2003)“…Three series of ring-substituted ether phospholipids were synthesized carrying N,N,N-trimethylammonium, N-methylpiperidino, or N-methylmorpholino headgroups…”
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Strategies in the design of prodrugs of anti-HIV agents
Published in Current topics in medicinal chemistry (01-01-2003)“…Control of AIDS requires development of special therapeutic strategies in order to reduce the level of monocyte/macrophage HIV infection, to prevent spread of…”
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Structure-activity relationships of antineoplastic ring-substituted ether phospholipid derivatives
Published in Cancer chemotherapy and pharmacology (01-09-2005)“…Previous studies have shown that alkylphosphocholines (APCs) exhibit strong antineoplastic activity against various tumour cell lines in vitro and in several…”
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An Observational Study to Assess the Molecular Epidemiology and Direct Medical Costs of Epidermal Growth Factor Receptor (EGFR) Mutations in Patients with Advanced EGFR Mutation-Positive Non-Small Cell Lung Cancer Treated with Afatinib in Real-World Clinical Settings in Greece
Published in Lung cancer (Auckland) (01-01-2021)“…Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are the preferred first-line option for patients with advanced, EGFR-mutant non-small…”
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Synthesis and Antiretroviral Evaluation of New Alkoxy and Aryloxy Phosphate Derivatives of 3‘-Azido-3‘-deoxythymidine
Published in Journal of medicinal chemistry (16-08-1996)“…A series of new ether lipid−3‘-azido-3‘-deoxythymidine (AZT) conjugates (11a−g) were synthesized and evaluated for anti-HIV activity. The effect of chirality…”
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Alkyl and Alkoxyethyl Antineoplastic Phospholipids
Published in Journal of medicinal chemistry (21-06-1996)“…Two series of phosphodiester ether lipid analogs with (N-methylmorpholino)ethyl or (N-methylpiperidino)ethyl polar head groups and long aliphatic or…”
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