Search Results - "Koucka, Kamila"
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The Role of TRIP6, ABCC3 and CPS1 Expression in Resistance of Ovarian Cancer to Taxanes
Published in International journal of molecular sciences (22-12-2021)“…The main problem precluding successful therapy with conventional taxanes is de novo or acquired resistance to taxanes. Therefore, novel experimental taxane…”
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Anticancer regimens containing third generation taxanes SB-T-121605 and SB-T-121606 are highly effective in resistant ovarian carcinoma model
Published in Frontiers in pharmacology (09-11-2022)“…Taxanes are widely used in the treatment of ovarian carcinomas. One of the main problems with conventional taxanes is the risk of development of multidrug…”
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Ketone-selenoesters as potential anticancer and multidrug resistance modulation agents in 2D and 3D ovarian and breast cancer in vitro models
Published in Scientific reports (21-04-2022)“…Long-term treatment of cancer with chemotherapeutics leads to the development of resistant forms that reduce treatment options. The main associated mechanism…”
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Multidrug Resistance Modulation Activity of Silybin Derivatives and Their Anti-inflammatory Potential
Published in Antioxidants (25-05-2020)“…Silybin is considered to be the main biologically active component of silymarin. Its oxidized derivative 2,3-dehydrosilybin typically occurs in silymarin in…”
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DNA Repair and Ovarian Carcinogenesis: Impact on Risk, Prognosis and Therapy Outcome
Published in Cancers (28-06-2020)“…There is ample evidence for the essential involvement of DNA repair and DNA damage response in the onset of solid malignancies, including ovarian cancer…”
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Association of lncRNA and transcriptome intersections with response to targeted therapy in metastatic renal cell carcinoma
Published in Oncology letters (01-09-2023)“…Long non-coding RNAs (lncRNAs) serve an important role in cancer progression and may be used as efficient molecular biomarkers. The present study aimed to…”
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