Search Results - "Kotzsch, M"

Co-detection of members of the urokinase plasminogen activator system in tumour tissue and serum correlates with a poor prognosis for soft-tissue sarcoma patients by Taubert, H, Würl, P, Greither, T, Kappler, M, Bache, M, Lautenschläger, C, Füssel, S, Meye, A, Eckert, A W, Holzhausen, H-J, Magdolen, V, Kotzsch, M

“…Background: The urokinase plasminogen activator (uPA) system is one of the best-investigated protease systems, both under physiological and pathological…”
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A pilot study on potential plasma hypoxia markers in the radiotherapy of non-small cell lung cancer: Osteopontin, carbonic anhydrase IX and vascular endothelial growth factor by Ostheimer, C., Bache, M., Güttler, A., Kotzsch, M., Vordermark, D.

“…Background Hypoxic radioresistance plays a critical role in the radiotherapy of cancer and adversely impacts prognosis and treatment response. This prospective…”
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Cathepsin B, Plasminogenactivator-inhibitor (PAI-1) and Plasminogenactivator-receptor (uPAR) are Prognostic Factors for Patients with Non-small Cell Lung Cancer by WERLE, B, KOTZSCH, M, MAGDOLEN, V, SCHMITT, M, HARBECK, N, LAH, T. T, KOS, J, GABRIJELCIC-GEIGER, D, SPIESS, E, SCHIRREN, J, EBERT, W, FIEHN, W, LUTHER, T

“…To evaluate the possible role of cysteine proteases and serine proteases, as well as their respective inhibitors and receptors, as new prognostic factors in…”
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Are overexpressed alternative survivin transcripts in human bladder cancer suitable targets for siRNA-mediated in vitro inhibition? by WUTTIG, D, KUNZE, D, HAKENBERG, O. W, MEYE, A, WIRTH, M. P, FUESSEL, S, TOMA, M, STADE, J, KOTZSCH, M, KAPPLER, M, TAUBERT, H, SCHWENZER, B, BARETTON, G

“…In order to reduce side effects of survivin-inhibiting anticancer therapies, we determined the expression of the survivin transcripts survivin-wild-type…”
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New ELISA for quantitation of human urokinase receptor (CD87) in cancer by Kotzsch, M, Luther, T, Harbeck, N, Ockert, D, Lutz, V, Noack, F, Grossmann, D, Albrecht, S, Kramer, M D, Lossnitzer, A, Grosser, M, Schmitt, M, Magdolen, V

“…The serine protease urokinase-type plasminogen activator (uPA), its inhibitor (PAI-1), and its receptor (uPAR; CD87) facilitate cancer cell invasion and…”
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Tissue factor antigen is elevated in patients with microvascular complications of diabetes mellitus by Zumbach, M, Hofmann, M, Borcea, V, Luther, T, Kotzsch, M, Müller, M, Hergesell, O, Andrassy, K, Ritz, E, Ziegler, R, Wahl, P, Nawroth, P P

“…Patients with late diabetic complications have increased levels of parameters indicating activation of coagulation (Takakashi et al., 1989; Ceriello, 1993;…”
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Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets by Müller, Ingrid, Klocke, Antje, Alex, Meike, Kotzsch, Matthias, Luther, Thomas, Morgenstern, Eberhard, Zieseniss, Susanne, Zahler, Stefan, Preissner, Klaus, Engelmann, Bernd

“…Although tissue factor (TF), the principial initiator of physiological coagulation and pathological thrombosis, has recently been proposed to be present in…”
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Tissue factor expression in normal and abnormal mammary gland by Luther, Thomas, Flössel, Conrad, Albrecht, Sybille, Kotzsch, Mathias, Müller, Martin

“…To the editor - In the February 1996 issue of Nature Medicine, Contrino et al. report that tissue factor (TF) can be localized by immunohistochemical methods…”
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294 Prognostic impact of urokinase-type plasminogen activator system components in patients with clear cell renal cell carcinoma by Füssel, S, Kotzsch, M, Erdmann, K, Taubert, H, Lohse-Fischer, A, Zastrow, S, Meinhardt, M, Bluemke, K, Fornara, P, Magdolen, V, Wirth, M.P

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C192 ANALYSIS OF COMPONENTS OF THE UROKINASE-TYPE PLASMINOGEN ACTIVATOR (UPA) SYSTEM IN TUMOR TISSUE AND SERUM OF PROSTATE CANCER PATIENTS by Fuessel, S, Kotzsch, M, Lohse-Fischer, A, Taubert, H, Magdolen, V, Froehner, M, Wirth, M.P

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An ELISA for tissue factor using monoclonal antibodies by Albrecht, S, Luther, T, Grossmann, H, Flössel, C, Kotzsch, M, Müller, M

“…Whereas tissue factor, a high-affinity cell-surface receptor and essential cofactor for the serine protease factor VII is constitutively present in certain…”
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Antisense-mediated hTERT Inhibition Specifically Reduces the Growth of Human Bladder Cancer Cells by KRAEMER, Kai, FUESSEL, Susanne, SCHMIDT, Uta, KOTZSCH, Matthias, SCHWENZER, Bernd, WIRTH, Manfred P, MEYE, Axel

“…Purpose: The expression of human telomerase reverse transcriptase (hTERT) is associated with cellular aging and tumorigenesis. It was found in nearly all…”
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Platelet-Associated Tissue Factor Contributes to the Collagen-Triggered Activation of Blood Coagulation by Zillmann, Andreas, Luther, Thomas, Müller, Ingrid, Kotzsch, Matthias, Spannagl, Michael, Kauke, Teresa, Oelschlägel, Uta, Zahler, Stefan, Engelmann, Bernd

“…The extravascular localization of tissue factor (TF), the central initiator of coagulation, is thought to ensure that thrombus formation is prevented in the…”
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Chemosensitization of bladder cancer cells by survivin-directed antisense oligodeoxynucleotides and siRNA by Fuessel, Susanne, Herrmann, Jana, Ning, Shuangli, Kotzsch, Matthias, Kraemer, Kai, Schmidt, Uta, Hakenberg, Oliver W., Wirth, Manfred P., Meye, Axel

“…Survivin is known to be overexpressed in numerous tumor types including human bladder cancer and to cause resistance to radiation and chemotherapy. Therefore,…”
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Knockdown of survivin expression by small interfering RNA reduces the clonogenic survival of human sarcoma cell lines independently of p53 by Kappler, Matthias, Bache, Matthias, Bartel, Frank, Kotzsch, Matthias, Panian, Matti, Würl, Peter, Blümke, Karen, Schmidt, Hannelore, Meye, Axel, Taubert, Helge

“…Survivin, a member of the inhibitors-of-apoptosis gene family, is overexpressed in many tumor types. Survivin is a prognostic marker of soft-tissue sarcomas,…”
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siRNA-mediated down-regulation of survivin inhibits bladder cancer cell growth by Ning, Shuangli, Fuessel, Susanne, Kotzsch, Matthias, Kraemer, Kai, Kappler, Matthias, Schmidt, Uta, Taubert, Helge, Wirth, Manfred P, Meye, Axel

“…Survivin is recognized as a general target in cancer therapy because of its selective overexpression in the majority of tumors. In bladder cancer (BCa), its…”
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Effect of Human Recombinant Interleukin-6 and Interleukin-8 on Monocyte Procoagulant Activity by Neumann, Franz-Josef, Ott, Ilka, Marx, Nikolaus, Luther, Thomas, Kenngott, Silke, Gawaz, Meinrad, Kotzsch, Mathias, Schomig, Albert

“…Interleukin (IL)-6 and IL-8 are important regulators of inflammatory responses in myocardial infarction. Induction of monocyte procoagulant activity (PCA) by…”
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Elevated Expression Level of Survivin Protein in Soft-Tissue Sarcomas Is a Strong Independent Predictor of Survival by KAPPLER, Matthias, KOTZSCH, Matthias, MEYE, Axel, BARTEL, Frank, FÜSSEL, Susanne, LAUTENSCHLÄGER, Christine, SCHMIDT, Uta, WÜRL, Peter, BACHE, Matthias, SCHMIDT, Hannelore, TAUBERT, Helge

“…Purpose: Survivin is a member of the inhibitor-of-apoptosis gene family and is known to be overexpressed in a number of tumor types. The aim of this study was…”
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Multitarget siRNA Inhibition of Antiapoptotic Genes (XIAP, BCL2, BCL-XL) in Bladder Cancer Cells by KUNZE, Doreen, WUTTIG, Daniela, FUESSEL, Susanne, KRAEMER, Kai, KOTZSCH, Matthias, MEYE, Axel, GRIMM, Marc-Oliver, HAKENBERG, Oliver W, WIRTH, Manfred P

“…Background: The knockdown of XIAP, BCL2 and BCL-X L by siRNAs represents a promising treatment option for bladder cancer (BCa) since the overexpression of…”
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Prognostic relevance of uPAR-del4/5 and TIMP-3 mRNA expression levels in breast cancer by Kotzsch, Matthias, Farthmann, Juliane, Meye, Axel, Fuessel, Susanne, Baretton, Gustavo, Tjan-Heijnen, Vivianne C.G., Schmitt, Manfred, Luther, Thomas, Sweep, Fred C.G.J., Magdolen, Viktor, Span, Paul N.

“…Recently, two components of important protease systems in cancer, i.e., the urokinase plasminogen activator receptor (uPAR) mRNA splice variant uPAR-del4/5 and…”
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