Search Results - "Kottke‐Marchant, K."

Diagnostic approach to microangiopathic hemolytic disorders by Kottke‐Marchant, K.

“…Thrombotic micro‐angiopathies (TMA) are a group of related disorders that are characterized by thrombosis of the microvasculature and associated organ…”
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Effect of 6% hydroxyethyl starch 130/0.4 on kidney and haemostatic function in cardiac surgical patients: a randomised controlled trial by Duncan, A. E., Jia, Y., Soltesz, E., Leung, S., Yilmaz, H.O., Mao, G., Timur, A. A., Kottke‐Marchant, K., Rogers, H. J., Ma, C., Ince, I., Karimi, N., Yagar, S., Trombetta, C., Sessler, D. I.

“…Summary Whether third‐generation hydroxyethyl starch solutions provoke kidney injury or haemostatic abnormalities in patients having cardiac surgery remains…”
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Aspirin resistance: position paper of the Working Group on Aspirin Resistance by MICHELSON, A. D., CATTANEO, M., EIKELBOOM, J. W., GURBEL, P., KOTTKE‐MARCHANT, K., KUNICKI, T. J., PULCINELLI, F. M., CERLETTI, C., RAO, A. K.

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Validation of a panel of ADAMTS13 assays for diagnosis of thrombotic thrombocytopenic purpura: activity, functional inhibitor, and autoantibody test by Nakashima, M. O., Zhang, X., Rogers, H. J., Vengal, L., Gibson Jr, B., Daly, T. M., Kottke-Marchant, K.

“…Summary Introduction Quantitation of ADAMTS13 activity, functional inhibitors, and autoantibodies is crucial in diagnosis and management of thrombotic…”
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Shear-Dependent Changes in the Three-Dimensional Structure of Human von Willebrand Factor by Siedlecki, Christopher A., Lestini, Brian J., Kottke-Marchant, Kandice, Eppell, Steven J., Wilson, David L., Marchant, Roger E.

“…The three-dimensional tertiary structure of human von Willebrand Factor (vWF) on a hydrophobic surface under aqueous conditions and different shear stress…”
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P2RY1 and P2RY12 polymorphisms and on-aspirin platelet reactivity in patients with coronary artery disease by TIMUR, A. A., MURUGESAN, G., ZHANG, L., AUNG, P. P., BARNARD, J., WANG, Q. K., GAUSSEM, P., SILVERSTEIN, R. L., BHATT, D. L., KOTTKE-MARCHANT, K.

“…Summary Introduction:  Association of P2RY1 and P2RY12 polymorphisms with on‐aspirin platelet reactivity was investigated. Materials and methods:  Platelet…”
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Prothrombin 20209C>T: 16 new cases, association with the 19911A>G polymorphism, and literature review by WARSHAWSKY, I., MAKKAR, V., RIMMERMAN, C., KOTTKE‐MARCHANT, K.

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Glycocalyx-mimetic dextran-modified poly(vinyl amine) surfactant coating reduces platelet adhesion on medical-grade polycarbonate surface by Sen Gupta, A., Wang, S., Link, E., Anderson, E.H., Hofmann, C., Lewandowski, J., Kottke-Marchant, K., Marchant, R.E.

“…A dextran-modified poly(vinyl amine) comb-like surfactant polymer, poly( N-vinyl dextran aldonamide -co-N-vinyl hexanamide) , that can surface-adsorb on…”
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Heparin-Induced Thrombocytopenia by Brieger, David B, Mak, Koon-Hou, Kottke-Marchant, Kandice, Topol, Eric J

“…Heparin-induced thrombocytopenia (HIT) is a potentially serious complication of heparin therapy and is being encountered more frequently in patients with…”
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External quality assurance of fibrinogen assays using normal plasma: results of the 2008 College of American Pathologists proficiency testing program in coagulation by Cunningham, Mark T, Olson, John D, Chandler, Wayne L, Van Cott, Elizabeth M, Eby, Charles S, Teruya, Jun, Hollensead, Sandra C, Adcock, Dorothy M, Allison, Paul M, Kottke-Marchant, Kandice K, Smith, Marc D

“…Proper diagnosis and therapy of fibrinogen deficiency requires high-quality fibrinogen assays. To assess the interlaboratory bias, precision, and grading of…”
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External quality assurance of antithrombin, protein C, and protein s assays: results of the College of American Pathologists proficiency testing program in thrombophilia by Cunningham, Mark T, Olson, John D, Chandler, Wayne L, Van Cott, Elizabeth M, Eby, Charles S, Teruya, Jun, Hollensead, Sandra C, Adcock, Dorothy M, Allison, Paul M, Kottke-Marchant, Kandice K, Smith, Marc D

“…Hereditary and acquired deficiencies of antithrombin (AT), protein C (PC), and protein S (PS) are risk factors for venous thromboembolism. Proper diagnosis…”
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Effect of hirudin vs heparin on haemostatic activity in patients with acute coronary syndromes by Kottke-Marchant, K., Bahit, M.C., Granger, C.B., Zoldhelyi, P., Ardissino, D., Brooks, L., Griffin, J.H., Potthoff, R.F., Van de Werf, F., Califf, R.M., Topol, E.J.

“…Aims We compared the effects of hirudin and heparin on thrombin generation and activity among 350 patients with acute coronary syndromes enrolled in the…”
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Molecular regulation of contractile smooth muscle cell phenotype: implications for vascular tissue engineering by Beamish, Jeffrey A, He, Ping, Kottke-Marchant, Kandice, Marchant, Roger E

“…The molecular regulation of smooth muscle cell (SMC) behavior is reviewed, with particular emphasis on stimuli that promote the contractile phenotype. SMCs can…”
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Phase I trial of simultaneously administered GM-CSF and IL-6 in patients with renal-cell carcinoma: Clinical and laboratory effects by Tate, J., Olencki, T., Finke, J., Kottke-Marchant, K., Rybicki, L. A., Bukowski, R.M.

“…Background: Metastatic renal-cell carcinoma is a neoplasm that is minimally responsive to cytotoxic chemotherapy. Tumor regression following therapy with…”
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A prospective, blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease by Gum, Patricia A, Kottke-Marchant, Kandice, Welsh, Patricia A, White, Jennifer, Topol, Eric J

“…This study was designed to determine if aspirin resistance is associated with clinical events. Aspirin resistance, defined by platelet function testing and…”
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Laboratory reporting of the international normalized ratio: progress and problems by Olson, John D, Brandt, John T, Chandler, Wayne L, Van Cott, Elizabeth M, Cunningham, Mark T, Hayes, Timothy E, Kottke-Marchant, Kandice K, Makar, Robert S, Uy, Arby B, Wang, Edward C

“…The international normalized ratio (INR) is widely used to monitor oral anticoagulation and to evaluate patients with coagulation disorders. To examine the…”
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Biocompatibility of heparin-coated extracorporeal bypass circuits: A randomized, masked clinical trial by Muehrcke, Derek D., McCarthy, Patrick M., Kottke-Marchant, Kandice, Harasaki, Hiroaki, Pierre-Yared, Jean, Borsh, Judith A., Ogella, David A., Cosgrove, Delos M.

“…Cardiopulmonary bypass circuits cause morbidity during cardiac operations. Plasma proteins and cellular components are stimulated by contact with the…”
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Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci by Saxena, Richa, Guo, Yiran, Peter, Inga, Gaunt, Tom R., Mega, Jessica L., Li, Yun R., Johnson, Toby, Bruinenberg, Marcel, Gilbert-Diamond, Diane, Rajagopalan, Ramakrishnan, Voight, Benjamin F., Barnard, John, Bauer, Florianne, Bhangale, Tushar, Burton, Paul R., Clarke, Robert, Cooper-DeHoff, Rhonda M., Crook, Errol D., Davey-Smith, George, Day, Ian N., Drenos, Fotios, Furlong, Clement E., Gibson, Quince, Gieger, Christian, Goel, Anuj, Gong, Yan, Hastie, Claire, Humphries, Steve E., Kim, Cecilia E., Kleber, Marcus, Kumari, Meena, Langaee, Taimour Y., Lawlor, Debbie A., Li, Mingyao, Lobmeyer, Maximilian T., Maitland-van der Zee, Anke-Hilse, Meijs, Matthijs F.L., Molony, Cliona M., Musani, Solomon K., Nelson, Christopher P., Newhouse, Stephen J., O'Connell, Jeffery R., Palmen, Jutta, Patel, Sanjey R., Pepine, Carl J., Pettinger, Mary, Price, Thomas S., Rafelt, Suzanne, Ranchalis, Jane, Rasheed, Asif, Rosenthal, Elisabeth, Ruczinski, Ingo, Shen, Haiqing, Spijkerman, Annemieke W.M., Stanton, Alice, Steffes, Michael W., Thorand, Barbara, van der Harst, Pim, van Iperen, Erik P.A., van Vliet-Ostaptchouk, Jana V., Verweij, Niek, Wolffenbuttel, Bruce H.R., Young, Taylor, Zafarmand, M. Hadi, Zmuda, Joseph M., Altshuler, David, Kao, W.H. Linda, Poulter, Neil, Caulfield, Mark, Bhatt, Deepak L., Curtis, Sean P., Danesh, John, Onland-Moret, N. Charlotte, Doevendans, Pieter A., Dorn, Gerald W., Farrall, Martin, FitzGerald, Garret A., Hamsten, Anders, Hofker, Marten H., Jarvik, Gail P., Klungel, Olaf H., Knowler, William C., März, Winfried, Munroe, Patricia B., Bielinski, Susan J., Rader, Daniel J., Reilly, Muredach P., Rich, Stephen S., Rotter, Jerome I., Saleheen, Danish, Schadt, Eric E., Shuldiner, Alan R., Talmud, Philippa J., de Bakker, Paul I.W., McCaffery, Jeanne, Wijmenga, Cisca, Wilson, James G., Bowden, Donald W., Siscovick, David S., Keating, Brendan J.

“…To identify genetic factors contributing to type 2 diabetes (T2D), we performed large-scale meta-analyses by using a custom ∼50,000 SNP genotyping array (the…”
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Affinity manipulation of surface-conjugated RGD peptide to modulate binding of liposomes to activated platelets by Huang, Guofeng, Zhou, Zhongmin, Srinivasan, Rekha, Penn, Marc S, Kottke-Marchant, Kandice, Marchant, Roger E, Gupta, Anirban S

“…Abstract Platelet adhesion, activation and fibrinogen-mediated aggregation are primary events in vascular thrombosis and occlusion. An injectable delivery…”
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Reduced expression of platelet surface glycoprotein receptor IIb/IIIa at hyperthermic temperatures by Pasha, R, Benavides, M, Kottke-Marchant, K, Harasaki, H

“…Hyperthermic temperatures exist from the heat dissipation of the implantable energy source of an artificial heart. This procedure as well as therapies for…”
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