Search Results - "Kottick, Andrew"
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Unravelling cell type-specific responses to Parkinson's Disease at single cell resolution
Published in Molecular neurodegeneration (20-01-2024)“…Parkinson's Disease (PD) is the second most common neurodegenerative disorder. The pathological hallmark of PD is loss of dopaminergic neurons and the presence…”
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Transient Suppression of Dbx1 PreBötzinger Interneurons Disrupts Breathing in Adult Mice
Published in PloS one (09-09-2016)“…Interneurons derived from Dbx1-expressing precursors located in the brainstem preBötzinger complex (preBötC) putatively form the core oscillator for…”
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Correction: Unravelling cell type-specific responses to Parkinson's Disease at single cell resolution
Published in Molecular neurodegeneration (25-03-2024)Get full text
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Transcriptome of neonatal preBötzinger complex neurones in Dbx1 reporter mice
Published in Scientific reports (17-08-2017)“…We sequenced the transcriptome of brainstem interneurons in the specialized respiratory rhythmogenic site dubbed preBötzinger Complex (preBötC) from newborn…”
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Dbx1 precursor cells are a source of inspiratory XII premotoneurons
Published in eLife (19-12-2015)“…All behaviors require coordinated activation of motoneurons from central command and premotor networks. The genetic identities of premotoneurons providing…”
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Laser ablation of Dbx1 neurons in the pre-Bötzinger complex stops inspiratory rhythm and impairs output in neonatal mice
Published in eLife (15-07-2014)“…To understand the neural origins of rhythmic behavior one must characterize the central pattern generator circuit and quantify the population size needed to…”
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Synaptic Depression Influences Inspiratory-Expiratory Phase Transition in Dbx1 Interneurons of the preBötzinger Complex in Neonatal Mice
Published in The Journal of neuroscience (19-08-2015)“…The brainstem preBötzinger complex (preBötC) generates the rhythm underlying inspiratory breathing movements and its core interneurons are derived from…”
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Fate mapping neurons and glia derived from Dbx1‐expressing progenitors in mouse preBötzinger complex
Published in Physiological reports (01-06-2017)“…The brainstem preBötzinger complex (preBötC) generates the inspiratory breathing rhythm, and its core rhythmogenic interneurons are derived from…”
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Developmental, Physiological, and Transcriptomic Analyses of Neurons Involved in the Generation of Mammalian Breathing
Published 01-01-2016“…Breathing is a rhythmic motor behavior with obvious physiological importance: breathing movements are essential for respiration, which sustains homeostasis and…”
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Dissertation -
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Identification of the pre‐Bötzinger complex inspiratory center in calibrated “sandwich” slices from newborn mice with fluorescent Dbx1 interneurons
Published in Physiological reports (01-08-2014)“…Inspiratory active pre‐Bötzinger complex (preBötC) networks produce the neural rhythm that initiates and controls breathing movements. We previously identified…”
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Transmission of the respiratory rhythm to trigeminal and hypoglossal motor neurons in the American Bullfrog ( Lithobates catesbeiana )
Published in Respiratory physiology & neurobiology (15-08-2013)“…Highlights • Investigated signal transmitted from respiratory oscillators to motor neuron. • Transmission dependent on glutamate. • Both NMDA and non-NMDA…”
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Evidence for a distributed respiratory rhythm generating network in the goldfish (Carsssius auratus)
Published in Advances in experimental medicine and biology (01-01-2010)“…Central pattern generators located in the brainstem regulate ventilatory behaviors in vertebrates. The development of the isolated brainstem preparation has…”
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