Search Results - "Kotrba, Johanna"

Mast Cells in the Skin: Defenders of Integrity or Offenders in Inflammation? by Voss, Martin, Kotrba, Johanna, Gaffal, Evelyn, Katsoulis-Dimitriou, Konstantinos, Dudeck, Anne

“…Mast cells (MCs) are best-known as key effector cells of immediate-type allergic reactions that may even culminate in life-threatening anaphylactic shock…”
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Mast cells acquire MHCII from dendritic cells during skin inflammation by Dudeck, Jan, Medyukhina, Anna, Fröbel, Julia, Svensson, Carl-Magnus, Kotrba, Johanna, Gerlach, Michael, Gradtke, Ann-Christine, Schröder, Bernd, Speier, Stephan, Figge, Marc Thilo, Dudeck, Anne

“…Mast cells (MCs) and dendritic cells (DCs) are essential innate sentinels populating host-environment interfaces. Using longitudinal intravital multiphoton…”
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Ionic mitigation of CD4+ T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc by Krone, Anna, Fu, Yan, Schreiber, Simon, Kotrba, Johanna, Borde, Loisa, Nötzold, Aileen, Thurm, Christoph, Negele, Jonas, Franz, Tobias, Stegemann-Koniszewski, Sabine, Schreiber, Jens, Garbers, Christoph, Shukla, Aniruddh, Geffers, Robert, Schraven, Burkhart, Reinhold, Dirk, Dudeck, Anne, Reinhold, Annegret, Müller, Andreas J., Kahlfuss, Sascha

“…T helper (Th) cells provide immunity to pathogens but also contribute to detrimental immune responses during allergy and autoimmunity. Th2 cells mediate…”
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Mast Cell Functions Linking Innate Sensing to Adaptive Immunity by Katsoulis-Dimitriou, Konstantinos, Kotrba, Johanna, Voss, Martin, Dudeck, Jan, Dudeck, Anne

“…Although mast cells (MCs) are known as key drivers of type I allergic reactions, there is increasing evidence for their critical role in host defense. MCs not…”
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Investigation of the Prognostic Role of Carbonic Anhydrase 9 (CAIX) of the Cellular mRNA/Protein Level or Soluble CAIX Protein in Patients with Oral Squamous Cell Carcinoma by Eckert, Alexander W, Horter, Susanne, Bethmann, Daniel, Kotrba, Johanna, Kaune, Tom, Rot, Swetlana, Bache, Matthias, Bilkenroth, Udo, Reich, Waldemar, Greither, Thomas, Wickenhauser, Claudia, Vordermark, Dirk, Taubert, Helge, Kappler, Matthias

“…s Carbonic anhydrase 9 (CAIX) is an important protein that stabilizes the extracellular pH value and is transcriptionally regulated by hypoxia-inducible factor…”
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Causes and Consequences of A Glutamine Induced Normoxic HIF1 Activity for the Tumor Metabolism by Kappler, Matthias, Pabst, Ulrike, Weinholdt, Claus, Taubert, Helge, Rot, Swetlana, Kaune, Tom, Kotrba, Johanna, Porsch, Martin, Güttler, Antje, Bache, Matthias, Krohn, Knut, Bull, Fabian, Riemann, Anne, Wickenhauser, Claudia, Seliger, Barbara, Schubert, Johannes, Al-Nawas, Bilal, Thews, Oliver, Grosse, Ivo, Vordermark, Dirk, Eckert, Alexander W

“…The transcription factor hypoxia-inducible factor 1 (HIF1) is the crucial regulator of genes that are involved in metabolism under hypoxic conditions, but…”
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Prediction of regulatory targets of alternative isoforms of the epidermal growth factor receptor in a glioblastoma cell line by Weinholdt, Claus, Wichmann, Henri, Kotrba, Johanna, Ardell, David H, Kappler, Matthias, Eckert, Alexander W, Vordermark, Dirk, Grosse, Ivo

“…The epidermal growth factor receptor (EGFR) is a major regulator of proliferation in tumor cells. Elevated expression levels of EGFR are associated with…”
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Prognostic impact of mRNA levels of LGR5 transcript variants in OSCC patients by Rot, Swetlana, Kaune, Tom, Taubert, Helge, Greither, Thomas, Kotrba, Johanna, Güttler, Antje, Wichmann, Henri, Bilkenroth, Udo, Wienke, Andreas, Al-Nawas, Bilal, Bache, Matthias, Vordermark, Dirk, Wickenhauser, Claudia, Bethmann, Daniel, Eckert, Alexander W, Kappler, Matthias

“…The human leucine-rich, repeat-containing G protein-coupled receptor 5 (LGR5) is a stem cell marker in numerous adult tissues and is overexpressed in a large…”
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Mast cells: The Janus of type 2 inflammation by Kotrba, Johanna, Dudeck, Anne

“…Mast cells (MCs) are effectors in type 2 immunity, well known for their detrimental roles in allergy. In this issue of Immunity, Alhallak et al. now identify a…”
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P4HA1: A single-gene surrogate of hypoxia signatures in oral squamous cell carcinoma patients by Kappler, Matthias, Kotrba, Johanna, Kaune, Tom, Bache, Matthias, Rot, Swetlana, Bethmann, Daniel, Wichmann, Henri, Güttler, Antje, Bilkenroth, Udo, Horter, Susanne, Gallwitz, Lisa, Kessler, Jacqueline, Greither, Thomas, Taubert, Helge, Eckert, Alexander W., Vordermark, Dirk

“…Hypoxia gene expression signatures are of high prognostic value for head and neck cancer patients. Recently, the prognostic information of a multiple-gene…”
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Directional mast cell degranulation of tumor necrosis factor into blood vessels primes neutrophil extravasation by Dudeck, Jan, Kotrba, Johanna, Immler, Roland, Hoffmann, Aaron, Voss, Martin, Alexaki, Vasileia Ismini, Morton, Lorena, Jahn, Stephan René, Katsoulis-Dimitriou, Konstantinos, Winzer, Simon, Kollias, Georg, Fischer, Thomas, Nedospasov, Sergei A., Dunay, Ildiko Rita, Chavakis, Triantafyllos, Müller, Andreas J., Schraven, Burkhart, Sperandio, Markus, Dudeck, Anne

“…Tissue resident mast cells (MCs) rapidly initiate neutrophil infiltration upon inflammatory insult, yet the molecular mechanism is still unknown. Here, we…”
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Mast Cells Are Critical Regulators of Bone Fracture–Induced Inflammation and Osteoclast Formation and Activity by Kroner, Jochen, Kovtun, Anna, Kemmler, Julia, Messmann, Joanna J, Strauss, Gudrun, Seitz, Sebastian, Schinke, Thorsten, Amling, Michael, Kotrba, Johanna, Froebel, Julia, Dudeck, Jan, Dudeck, Anne, Ignatius, Anita

“…ABSTRACT Mast cells, important sensor and effector cells of the immune system, may influence bone metabolism as their number is increased in osteoporotic…”
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Engulfment of mast cell secretory granules on skin inflammation boosts dendritic cell migration and priming efficiency by Dudeck, Jan, Froebel, Julia, Kotrba, Johanna, Lehmann, Christian H.K., Dudziak, Diana, Speier, Stephan, Nedospasov, Sergei A., Schraven, Burkhart, Dudeck, Anne

“…Mast cells (MCs) are best known as key effector cells of allergic reactions, but they also play an important role in host defense against pathogens. Despite…”
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