Search Results - "Kotler, Mónica L"

Deregulation of mitochondria-shaping proteins Opa-1 and Drp-1 in manganese-induced apoptosis by Alaimo, Agustina, Gorojod, Roxana M, Beauquis, Juan, Muñoz, Manuel J, Saravia, Flavia, Kotler, Mónica L

“…Mitochondria are dynamic organelles that undergo fusion and fission processes. These events are regulated by mitochondria-shaping proteins. Changes in the…”
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The extrinsic and intrinsic apoptotic pathways are involved in manganese toxicity in rat astrocytoma C6 cells by Alaimo, Agustina, Gorojod, Roxana M., Kotler, Mónica L.

“…► We studied the molecular mechanisms involved in Mn neurotoxicity in astrocytoma cells. ► Mn cytotoxicity is mediated by reactive oxygen species generation. ►…”
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Focal adhesion kinase, RhoA, and p38 mitogen‐activated protein kinase modulates apoptosis mediated by angiotensin II AT2 receptors by Manzur, María J., Aguilera, Milton O., Kotler, Mónica L., Berón, Walter, Ciuffo, Gladys M.

“…Apoptosis plays an important role in cellular processes such as development, differentiation, and homeostasis. Although the participation of angiotensin II…”
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Manganese induces mitochondrial dynamics impairment and apoptotic cell death: A study in human Gli36 cells by Alaimo, Agustina, Gorojod, Roxana M., Miglietta, Esteban A., Villarreal, Alejandro, Ramos, Alberto J., Kotler, Mónica L.

“…•Gli36 glioma cells strongly express the astrocytic markers GFAP and S100B.•Mn cytotoxicity triggers a caspase-dependent mitochondrial apoptotic pathway.•Mn…”
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Improved Enzymatic Procedure for the Synthesis of Anandamide and N-Fatty Acylalkanolamine Analogues: A Combination Strategy to Antitumor Activity by Quintana, Paula G., García Liñares, Guadalupe, Chanquia, Santiago N., Gorojod, Roxana M., Kotler, Mónica L., Baldessari, Alicia

“…Twenty N‐fatty acylamines from linolenic and arachidonic acids, fifteen of them new compounds, were obtained through Candida antarctica B lipase‐catalyzed…”
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Comparative toxicity of PEG and folate-derived blue-emitting silicon nanoparticles: in vitro and in vivo studies by Calienni, M Natalia, Lillo, Cristian R, Prieto, M Jimena, Gorojod, Roxana M, V Alonso, Silvia Del, Kotler, Mónica L, Gonzalez, Mónica C, Montanari, Jorge

“…Amino functionalization is a first step modification aiming to achieve biomedical applications of silicon nanoparticles, for example, for photodynamic therapy…”
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Toward biomedical application of amino-functionalized silicon nanoparticles by Lillo, Cristian R, Natalia Calienni, María, Gorojod, Roxana M, Rivas Aiello, María Belén, Rodriguez Sartori, Damián, Prieto, María Jimena, Alonso, Silvia del V, Kotler, Mónica L, Gonzalez, Mónica C, Montanari, Jorge

“…Silicon blue-emitting nanoparticles (NPs) are promising effectors for photodynamic therapy and radiotherapy, because of their production of reactive oxygen…”
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Impact of Iron Incorporation on 2–4 nm Size Silicon Nanoparticles Properties by Romero, Juan J, Wegmann, Marc, Rodríguez, Hernán B, Lillo, Cristian, Rubert, Aldo, Klein, Stefanie, Kotler, Mónica L, Kryschi, Carola, Gonzalez, Mónica C

“…Iron-containing silicon nanoparticles were synthesized in an attempt to understand the effect of iron on the silicon nanoparticle (SiNP) photoluminescence and…”
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Silicon Nanoparticle Photophysics and Singlet Oxygen Generation by Llansola Portolés, Manuel J, David Gara, Pedro M, Kotler, Mónica L, Bertolotti, Sonia, San Román, Enrique, Rodríguez, Hernán B, Gonzalez, Mónica C

“…The effect of molecular oxygen and water on the blue photoluminescence of silicon nanoparticles synthesized by anodic oxidation of silicon wafers and surface…”
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ROS enhancement by silicon nanoparticles in X-ray irradiated aqueous suspensions and in glioma C6 cells by David Gara, Pedro M., Garabano, Natalia I., Llansola Portoles, Manuel J., Moreno, M. Sergio, Dodat, Diego, Casas, Oscar R., Gonzalez, Mónica C., Kotler, Mónica L.

“…The capability of silicon nanoparticles to increase the yield of reactive species upon 4 MeV X-ray irradiation of aqueous suspensions and C6 glioma cell…”
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Focal adhesion kinase, RhoA, and p38 mitogen-activated protein kinase modulates apoptosis mediated by angiotensin II AT 2 receptors by Manzur, María J, Aguilera, Milton O, Kotler, Mónica L, Berón, Walter, Ciuffo, Gladys M

“…Apoptosis plays an important role in cellular processes such as development, differentiation, and homeostasis. Although the participation of angiotensin II…”
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From the Cover: Vulnerability of C6 Astrocytoma Cells After Single-Compound and Joint Exposure to Type I and Type II Pyrethroid Insecticides by Romero, Delfina M, Berardino, Bruno G, Wolansky, Marcelo J, Kotler, Mónica L

“…A primary mode-of-action of all pyrethroid insecticides (PYRs) is the disruption of the voltage-gated sodium channel electrophysiology in neurons of target…”
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Manganese activates the mitochondrial apoptotic pathway in rat astrocytes by modulating the expression of proteins of the Bcl-2 family by Gonzalez, Laura E., Juknat, A. Ana, Venosa, Andrea J., Verrengia, Noemi, Kotler, Mónica L.

“…Manganese induces the central nervous system injury leading to manganism, by mechanisms not completely understood. Chronic exposure to manganese generates…”
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Amyotrophic lateral sclerosis‐immunoglobulins selectively interact with neuromuscular junctions expressing P/Q‐type calcium channels by Gonzalez, Laura E., Kotler, Mónica L., Vattino, Lucas G., Conti, Eugenia, Reisin, Ricardo C., Mulatz, Kirk J., Snutch, Terrance P., Uchitel, Osvaldo D.

“…J. Neurochem. (2011) 119, 826–847. Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by a gradual loss of motoneurons. The…”
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Microglial autophagy is impaired by prolonged exposure to β-amyloid peptides: evidence from experimental models and Alzheimer’s disease patients by Pomilio, Carlos, Gorojod, Roxana M., Riudavets, Miguel, Vinuesa, Angeles, Presa, Jessica, Gregosa, Amal, Bentivegna, Melisa, Alaimo, Agustina, Alcon, Soledad Porte, Sevlever, Gustavo, Kotler, Monica L., Beauquis, Juan, Saravia, Flavia

“…Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by the presence of misfolded proteins, amyloid-β (Aβ) aggregates, and…”
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Comparative toxicity of PEG and folate-derived blue-emitting silicon nanoparticles by Calienni, M Natalia, Lillo, Cristian R, Prieto, M Jimena, Gorojod, Roxana M, V Alonso, Silvia del, Kotler, Mónica L, Gonzalez, Mónica C, Montanari, Jorge

“…Amino functionalization is a first step modification aiming to achieve biomedical applications of silicon nanoparticles, for example, for photodynamic therapy…”
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Castration Increases Cell Damage Induced by Porphyrins in the Harderian Gland of Male Syrian Hamster. Necrosis and Not Apoptosis Mediates the Subsequent Cell Death by Antolı́n, Isaac, Rodrı́guez, Carmen, Urı́a, Higinio, Sáinz, Rosa M, Mayo, Juan C, Kotler, Mónica L, Rodrı́guez-Colunga, Marı́a J, Tolivia, Delio, Menéndez-Peláez, Armando

“…It is known that the Harderian gland of male Syrian hamster synthesizes a much smaller amount of porphyrins than the gland of the female and that castration…”
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Neurohormone melatonin prevents cell damage: effect on gene expression for antioxidant enzymes by Antolín, I, Rodríguez, C, Saínz, R M, Mayo, J C, Uría, H, Kotler, M L, Rodríguez-Colunga, M J, Tolivia, D, Menéndez-Peláez, A

“…It is well known that porphyrins cause a toxic light-mediated effect due to their capability to generate free radicals. Several reports have proved that…”
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Porphyrin accumulation in the harderian glands of female Syrian hamster results in mitochondrial damage and cell death by Antolín, I, Uría, H, Tolivia, D, Rodríguez-Colunga, M J, Rodríguez, C, Kotler, M L, Menéndez-Peláez, A

“…The Harderian glands of female Syrian hamsters contain very high concentrations of protoporphyrin (in the range of micrograms per mg of tissue) which…”
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Studies on Uroporphyrinogen Biosynthesis in Pig Liver by Fumagalli, Silvia A., Kotier, Monica L., Rossetti, María V., del C. Batlle, Alcira M.

“…Porphobilinogen-deaminase (PBG-D) and PBG-D-isomerase complex (PBG-D-I) from pig liver were isolated and partially purified. Uroporphyrinogen I and III…”
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