Search Results - "Kotiranta, Titta"

Hydrophilic Auristatin Glycoside Payload Enables Improved Antibody-Drug Conjugate Efficacy and Biocompatibility by Satomaa, Tero, Pynnönen, Henna, Vilkman, Anja, Kotiranta, Titta, Pitkänen, Virve, Heiskanen, Annamari, Herpers, Bram, Price, Leo, Helin, Jari, Saarinen, Juhani

“…Antibody-drug conjugates (ADCs) offer a combination of antibody therapy and specific delivery of potent small-molecule payloads to target cells. The properties…”
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Targeting CD33+ Acute Myeloid Leukemia with GLK-33, a Lintuzumab-Auristatin Conjugate with a Wide Therapeutic Window by Satomaa, Tero, Pynnönen, Henna, Aitio, Olli, Hiltunen, Jukka O, Pitkänen, Virve, Lähteenmäki, Tuula, Kotiranta, Titta, Heiskanen, Annamari, Hänninen, Anna-Liisa, Niemelä, Ritva, Helin, Jari, Kuusanmäki, Heikki, Vänttinen, Ida, Rathod, Ramji, Nieminen, Anni I, Yatkin, Emrah, Heckman, Caroline A, Kontro, Mika, Saarinen, Juhani

“…CD33 (Siglec-3) is a cell surface receptor expressed in approximately 90% of acute myeloid leukemia (AML) blasts, making it an attractive target for therapy of…”
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