Search Results - "Kotil, Seyfullah"
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Rationally designing antisense therapy to keep up with evolving bacterial resistance
Published in PloS one (15-01-2019)“…Antisense molecules used as antibiotics offer the potential to keep up with acquired resistance, by redesigning the sequence of an antisense. Once bacteria…”
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Emergence of evolutionarily stable communities through eco-evolutionary tunnelling
Published in Nature ecology & evolution (01-10-2018)“…Ecological and evolutionary dynamics of communities are inexorably intertwined. The ecological state determines the fate of newly arising mutants, and…”
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Using a real-world network to model the trade-off between stay-at-home restriction, vaccination, social distancing and working hours on COVID-19 dynamics
Published in PeerJ (San Francisco, CA) (15-12-2022)“…Human behaviour, economic activity, vaccination, and social distancing are inseparably entangled in epidemic management. This study aims to investigate the…”
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Machine learning aided multiscale modelling of the HIV-1 infection in the presence of NRTI therapy
Published in PeerJ (San Francisco, CA) (31-03-2023)“…Human Immunodeficiency Virus (HIV) is one of the most common chronic infectious diseases in humans. Extending the expected lifetime of patients depends on the…”
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Prediction of HIV-1 protease resistance using genotypic, phenotypic, and molecular information with artificial neural networks
Published in PeerJ (San Francisco, CA) (21-03-2023)“…Drug resistance is a primary barrier to effective treatments of HIV/AIDS. Calculating quantitative relations between genotype and phenotype observations for…”
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Mathematical modelling of antibiotic interaction on evolution of antibiotic resistance: an analytical approach
Published in PeerJ (San Francisco, CA) (26-02-2024)“…The emergence and spread of antibiotic-resistant pathogens have led to the exploration of antibiotic combinations to enhance clinical effectiveness and counter…”
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Characterization of genomic, physiological, and probiotic features Lactiplantibacillus plantarum DY46 strain isolated from traditional lactic acid fermented shalgam beverage
Published in Food bioscience (01-04-2022)“…Lactiplantibacillus plantarum is a significant probiotic where it could be found in ubiquitous niches. In this study, a new Lb. plantarum strain DY46 was…”
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Investigating the eco-evolutionary tunnels for establishing cooperative communities
Published in Mathematical biosciences (01-02-2023)“…Diversity is abundant among microbial communities. Understanding the assembly of diverse microbial communities is a significant challenge. One of the recent…”
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Effect of sojourn time distributions on the early dynamics of COVID-19 outbreak
Published in Nonlinear dynamics (01-06-2023)“…Compartmental models are commonly used in practice to investigate the dynamical response of infectious diseases such as the COVID-19 outbreak. Such models…”
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Exploring the binding capacity of lactic acid bacteria derived bacteriocins against RBD of SARS-CoV-2 Omicron variant by molecular simulations
Published in Journal of biomolecular structure & dynamics (21-12-2023)“…The changes in the SARS-CoV-2 genome have resulted in the emergence of new variants. Some of the variants have been classified as variants of concern (VOC)…”
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Improving Predictive Efficacy for Drug Resistance in Novel HIV‑1 Protease Inhibitors through Transfer Learning Mechanisms
Published in Journal of chemical information and modeling (28-10-2024)“…The human immunodeficiency virus presents a significant global health challenge due to its rapid mutation and the development of resistance mechanisms against…”
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In Silico Analysis of Bacteriocins from Lactic Acid Bacteria Against SARS-CoV-2
Published in Probiotics and antimicrobial proteins (01-02-2023)“…The COVID-19 pandemic caused by a novel coronavirus (SARS-CoV-2) is a serious health concern in the twenty-first century for scientists, health workers, and…”
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