Search Results - "Kothari, Sweta T."
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A Computational Model for Docking of Noncompetitive Neuraminidase Inhibitors and Probing their Binding Interactions with Neuraminidase of Influenza Virus H5N1
Published in Current computer-aided drug design (01-12-2016)“…With cases of emergence of drug resistance to the current competitive inhibitors of neuraminidase (NA) such as oseltamivir and zanamavir, there is a present…”
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Novel evidence of microglial immune response in impairment of Dengue infection of CNS
Published in Immunobiology (1979) (01-10-2015)“…Highlights • First direct evidence of microglial role in Dengue. • First report on infection of BV2 cells by Dengue virus. • First molecular leads into the…”
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(Copper–curcumin) β-cyclodextrin vaginal gel: Delivering a novel metal–herbal approach for the development of topical contraception prophylaxis
Published in European journal of pharmaceutical sciences (18-12-2014)“…Delivering a safe and effective topical vaginal contraceptive is the need of present era. We explored the potential of a metal (copper) and herbal moiety…”
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Brain-Derived Neurotrophic Factor in children with Autism Spectrum Disorder
Published in Annals of Neurosciences (01-10-2014)“…Autism Spectrum Disorder (ASD) is a complex neurobehavioral syndrome with no known biomarker so far for early detection. It has been challenging, both to…”
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Structure-aided drug development of potential neuraminidase inhibitors against pandemic H1N1 exploring alternate binding mechanism
Published in Molecular diversity (01-11-2019)“…The rate of mutability of pathogenic H1N1 influenza virus is a threat. The emergence of drug resistance to the current competitive inhibitors of neuraminidase,…”
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Design, synthesis and evaluation of chalcones as H1N1 Neuraminidase inhibitors
Published in Medicinal chemistry research (01-04-2018)“…A series of chalcone derivatives ( 1a – 2i ) were designed based on isoliquiritigenin (the most active natural chalcone non-competitive neuraminidase (NA)…”
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Seroprevalence of Measles, Mumps, and Rubella Antibodies in College Students in Mumbai, India
Published in Viral immunology (01-04-2016)“…Measles, Mumps, and Rubella (MMR) are vaccine preventable viral infections, which cause significant mortality and morbidity globally. Increased incidence rates…”
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Drug susceptibility of influenza A/H3N2 strains co-circulating during 2009 influenza pandemic: First report from Mumbai
Published in Infection, genetics and evolution (01-01-2015)“…•Influenza A/H3N2 isolates harbor mutations known to confer resistance to amantadine.•No know mutations conferring resistance to neuraminidase inhibitors were…”
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Molecular analysis of genetic variation in angiotensin I-converting enzyme identifies no association with sporting ability: First report from Indian population
Published in Indian journal of human genetics (01-01-2012)“…Introduction: A polymorphism in the angiotensin-converting enzyme (ACE) gene was the first performance enhancing polymorphisms (PEPs) to be identified and…”
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Estimation of mRNA levels of interleukin (IL)-10, tumor necrosis factor (TNF)-α, IL-4 and interferon (IFN)-γ in HIV infected children in Mumbai
Published in Indian journal of clinical biochemistry (01-03-2006)“…Cytokines, viral load and opportunistic infections play an important role in HIV-disease progression. Hundred children vertically infected with HIV were…”
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Estimation of mRNA levels of interleukin (IL)-10, tumor necrosis factor (TNF)-[alpha], IL-4 and interferon (IFN)-[gamma] in HIV infected children in Mumbai
Published in Indian journal of clinical biochemistry (01-03-2006)“…Cytokines, viral load and opportunistic infections play an important role in HIV-disease progression. Hundred children vertically infected with HIV were…”
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