Search Results - "Kotake, M."

High incidence of interstitial lung disease following practical use of osimertinib in patients who had undergone immediate prior nivolumab therapy by Kotake, M., Murakami, H., Kenmotsu, H., Naito, T., Takahashi, T.

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S-1 and irinotecan plus bevacizumab versus mFOLFOX6 or CapeOX plus bevacizumab as first-line treatment in patients with metastatic colorectal cancer (TRICOLORE): a randomized, open-label, phase III, noninferiority trial by Yamada, Y., Denda, T., Gamoh, M., Iwanaga, I., Yuki, S., Shimodaira, H., Nakamura, M., Yamaguchi, T., Ohori, H., Kobayashi, K., Tsuda, M., Kobayashi, Y., Miyamoto, Y., Kotake, M., Shimada, K., Sato, A., Morita, S., Takahashi, S., Komatsu, Y., Ishioka, C.

“…Combination therapy with oral fluoropyrimidine and irinotecan has not yet been established as first-line treatment of metastatic colorectal cancer (mCRC). We…”
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Randomized clinical trial of skin closure by subcuticular suture or skin stapling after elective colorectal cancer surgery by Kobayashi, S., Ito, M., Yamamoto, S., Kinugasa, Y., Kotake, M., Saida, Y., Kobatake, T., Yamanaka, T., Saito, N., Moriya, Y.

“…Background The best suture method to prevent incisional surgical‐site infection (SSI) after clean‐contaminated surgery has not been clarified. Methods Patients…”
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A randomized phase III trial comparing S-1 versus UFT as adjuvant chemotherapy for stage II/III rectal cancer (JFMC35-C1: ACTS-RC) by Oki, E., Murata, A., Yoshida, K., Maeda, K., Ikejiri, K., Munemoto, Y., Sasaki, K., Matsuda, C., Kotake, M., Suenaga, T., Matsuda, H., Emi, Y., Kakeji, Y., Baba, H., Hamada, C., Saji, S., Maehara, Y.

“…Preventing distant recurrence and achieving local control are important challenges in rectal cancer treatment, and use of adjuvant chemotherapy has been…”
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Updated analysis and exploratory analysis of primary tumor location in the TRICOLORE trial: A randomized phase III trial of S-1 and irinotecan plus bevacizumab versus mFOLFOX6 or CapeOX plus bevacizumab as first-line treatment for metastatic colorectal cancer by Nakamura, M, Takashima, A, Denda, T, Gamoh, M, Iwanaga, I, Komatsu, Y, Takahashi, M, Ohori, H, Sekikawa, T, Tsuda, M, Kobayashi, Y, Miyamoto, Y, Kotake, M, Ishioka, C, Shimada, K, Sato, A, Yuki, S, Morita, S, Takahashi, S, Yamaguchi, T

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The indications for a diverting stoma in low anterior resection for rectal cancer: a prospective multicentre study of 222 patients from Japanese cancer centers by Shiomi, A., Ito, M., Saito, N., Hirai, T., Ohue, M., Kubo, Y., Takii, Y., Sudo, T., Kotake, M., Moriya, Y.

“…Aim  The aim of the study was to determine the present state of diverting stoma construction in Japanese cancer centres and to investigate the relationship…”
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The application of omics technologies in the functional evaluation of inulin and inulin-containing prebiotics dietary supplementation by Tsurumaki, M, Kotake, M, Iwasaki, M, Saito, M, Tanaka, K, Aw, W, Fukuda, S, Tomita, M

“…Inulin, a natural renewable polysaccharide resource produced by various plants in nature, has been reported to possess a significant number of diverse…”
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Magnetic Shielding of an Adiabatic Demagnetization Refrigerator for TES Microcalorimeter Operation by Hishi, U., Fujimoto, R., Kunihisa, T., Takakura, S., Mitsude, T., Kamiya, K., Kotake, M., Hoshino, A., Shinozaki, K.

“…We are developing a compact adiabatic demagnetization refrigerator (ADR) dedicated for TES X-ray microcalorimeter operation. Ferric ammonium alum (FAA) was…”
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1051 Knockdown of LINE-1 Enhances Sensitivity to 5-FU in LINE-1-hypomethylated Colorectal Cancer Cell by Kawakami, K, Matsunoki, A, Kotake, M, Kaneko, M, Kitamura, H, Watanabe, G, Minamoto, T

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Discovery of a potent, metabolically stabilized resorcylic lactone as an anti-inflammatory lead by Du, H., Matsushima, T., Spyvee, M., Goto, M., Shirota, H., Gusovsky, F., Chiba, K., Kotake, M., Yoneda, N., Eguchi, Y., DiPietro, L., Harmange, J.-C., Gilbert, S., Li, X.-Y., Davis, H., Jiang, Y., Zhang, Z., Pelletier, R., Wong, N., Sakurai, H., Yang, H., Ito-Igarashi, H., Kimura, A., Kuboi, Y., Mizui, Y., Tanaka, I., Ikemori-Kawada, M., Kawakami, Y., Inoue, A., Kawai, T., Kishi, Y., Wang, Y.

“…With bioactivity-guided phenotype screenings, a potent anti-inflammatory compound f152A1 has been isolated, characterized and identified as the known natural…”
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Glucose transporter 2 concentrations in hyper- and hypothyroid rat livers by Mokuno, T, Uchimura, K, Hayashi, R, Hayakawa, N, Makino, M, Nagata, M, Kakizawa, H, Sawai, Y, Kotake, M, Oda, N, Nakai, A, Nagasaka, A, Itoh, M

“…The deterioration of glucose metabolism frequently observed in hyperthyroidism may be due in part to increased gluconeogenesis in the liver and glucose efflux…”
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Changes in lipid peroxidation and free radical scavengers in the brain of hyper- and hypothyroid aged rats by Mano, T, Sinohara, R, Sawai, Y, Oda, N, Nishida, Y, Mokumo, T, Asano, K, Ito, Y, Kotake, M, Hamada, M

“…To determine how lipid peroxides and free radical scavengers are changed in the brain of hyper- or hypothyroid rats, we examined the behavior of lipid peroxide…”
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Effects of thyroid hormone on coenzyme Q and other free radical scavengers in rat heart muscle by Mano, T, Sinohara, R, Sawai, Y, Oda, N, Nishida, Y, Mokuno, T, Kotake, M, Hamada, M, Masunaga, R, Nakai, A

“…Active oxygen species are reported to cause organ damage. This study was therefore designed to determine the behaviour of antioxidants and free radical…”
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1673P Efficacy and safety of 5 mg olanzapine for the prevention of carboplatin-induced nausea and vomiting in patients with thoracic malignancies: A prospective multicenter phase II study by Fujita, Y., Iihara, H., Shimokawa, M., Sakai, C., Ikemura, S., Hirose, C., Kotake, M., Funaguchi, N., Gomyo, T., Imai, H., Hakamata, J., Kaito, D., Minato, K., Arai, T., Kawazoe, H., Suzuki, A., Ohno, Y., Okura, H.

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Changes in free radical scavengers and lipid peroxide in thyroid glands of various thyroid disorders by Mano, T, Shinohara, R, Iwase, K, Kotake, M, Hamada, M, Uchimuro, K, Hayakawa, N, Hayashi, R, Nakai, A, Ishizuki, Y, Nagasaka, A

“…To clarify whether the changes of free radicals and its scavengers are induced by thyroid disorders, we measured levels of free radical scavengers and checked…”
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Reverse transcriptase is elevated in the thyroid tissue from Graves' disease patients by NAGASAKA, A, NAKAI, A, ODA, N, KOTAKE, M, IWASE, K, YOSHIDA, S

“…Hypertrophy of the thyroid gland in Graves' disease is related to an autoimmune response directed against TSH receptors found in thyroid cells. Recently,…”
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456P Practical use of osimertinib in Japanese patients with EGFR T790M mutation positive advanced non-small-cell lung cancer by Kotake, M., Murakami, H., Naito, T., Takahashi, T., Kenmotsu, H., Ono, A., Wakuda, K., Nakashima, K., Omori, S.

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456P Practical use of osimertinib in Japanese patients with EGFR T790M mutation positive advanced non-small-cell lung cancer by Kotake, M., Murakami, H., Naito, T., Takahashi, T., Kenmotsu, H., Ono, A., Wakuda, K., Nakashima, K., Omori, S.

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Reduction of activity, but no decrease in concentration, of erythrocyte Cu,Zn-superoxide dismutase by hyperglycaemia in diabetic patients by Kotake, M., Shinohara, R., Kato, K., Hayakawa, N., Hayashi, R., Uchimura, K., Makino, M., Nagata, M., Kakizawa, H., Nakagawa, H., Nagasaka, A., Itoh, M.

“…Cu,Zn‐superoxide dismutase (SOD) activity in erythrocytes is affected by various diseases, including diabetes mellitus (DM). We investigated changes in the…”
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475PUpdated analysis and exploratory analysis of primary tumor location in the TRICOLORE trial: A randomized phase III trial of S-1 and irinotecan plus bevacizumab versus mFOLFOX6 or CapeOX plus bevacizumab as first-line treatment for metastatic colorectal cancer by Nakamura, M, Takashima, A, Denda, T, Gamoh, M, Iwanaga, I, Komatsu, Y, Takahashi, M, Ohori, H, Sekikawa, T, Tsuda, M, Kobayashi, Y, Miyamoto, Y, Kotake, M, Ishioka, C, Shimada, K, Sato, A, Yuki, S, Morita, S, Takahashi, S, Yamaguchi, T

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