Search Results - "Kostun, Jan"

Molecular substratification of endometrial carcinomas with no special molecular profile (NSMP) by using a limited NGS custom panel may facilitate effective patient selection for the PIK3CA-targeted therapy by Ondič, Ondrej, Michalová, Květoslava, Švajdler, Marián, Presl, Jiří, Kosťun, Jan, Hájková, Veronika, Martínek, Petr, Michal, Michal

“…Endometrial carcinomas (EC) of no special molecular profile (NSMP) represent the largest molecular category of EC, comprising a mixture of tumors with…”
Get full text

Calreticulin exposure correlates with robust adaptive antitumor immunity and favorable prognosis in ovarian carcinoma patients by Kasikova, Lenka, Hensler, Michal, Truxova, Iva, Skapa, Petr, Laco, Jan, Belicova, Lucie, Praznovec, Ivan, Vosahlikova, Sarka, Halaska, Michael J., Brtnicky, Tomas, Rob, Lukas, Presl, Jiri, Kostun, Jan, Cremer, Isabelle, Ryska, Ales, Kroemer, Guido, Galluzzi, Lorenzo, Spisek, Radek, Fucikova, Jitka

“…BackgroundAdjuvanticity, which is the ability of neoplastic cells to deliver danger signals, is critical for the host immune system to mount spontaneous and…”
Get full text

One‐step nucleic acid amplification vs ultrastaging in the detection of sentinel lymph node metastasis in endometrial cancer patients by Kosťun, Jan, Pešta, Martin, Sláma, Jiří, Slunéčko, Robert, Vlasák, Pavel, Bouda, Jiří, Novotný, Zdeněk, Topolčan, Ondřej, Kučera, Radek, Kulda, Vlastimil, Houfková, Kateřina, Berezovskiy, Denis, Bartáková, Alena, Presl, Jiří

“…Background and Objectives Utilisation of the one‐step nucleic acid amplification (OSNA) molecular biology method for the detection of the metastatic…”
Get full text

Immunohistochemical and selected genetic reflex testing of all uterine leiomyosarcomas and STUMPs for ALK gene rearrangement may provide an effective screening tool in identifying uterine ALK-rearranged mesenchymal tumors by Ptáková, Nikola, Miesbauerová, Markéta, Kosťun, Ján, Grossmann, Petr, Šidlová, Henrieta, Pavelka, Jaroslav, Presl, Jiří, Alaghehbandan, Reza, Bouda, Jiří, Ondič, Ondrej

“…We examined the value of targeted molecular screening for the identification of uterine anaplastic lymphoma kinase (ALK)-rearranged mesenchymal tumors,…”
Get full text

CD44 as a cancer stem cell marker and its prognostic value in patients with ovarian carcinoma by Bartakova, Alena, Michalova, Kveta, Presl, Jiri, Vlasak, Pavel, Kostun, Jan, Bouda, Jiri

“…The aim of our study was to clarify whether the CD44 adhesion molecule as a cancer stem cell marker could also serve as a prognostic factor in patients with…”
Get full text

Diagnostic Reliability, Accuracy and Safety of Ultrasound-guided Biopsy and Ascites Puncture in Primarily Inoperable Ovarian Tumours by Vlasak, Pavel, Bouda, Jiri, Kostun, Jan, Berezovskiy, Denis, Zikan, Michal, Weinberger, Vit, Ondic, Ondrej, Rusavy, Zdenek, Kucera, Radek, Topolcan, Ondrej, Novotny, Zdenek, Presl, Jiri

“…Background/Aim: To compare the diagnostic reliability, accuracy and safety of ultrasound-guided biopsy (Tru-Cut biopsy) and ascites puncture in patients with a…”
Get full text

The annual recurrence risk model for tailored surveillance strategy in patients with cervical cancer by Cibula, David, Dostálek, Lukáš, Jarkovsky, Jiri, Mom, Constantijne H., Lopez, Aldo, Falconer, Henrik, Fagotti, Anna, Ayhan, Ali, Kim, Sarah H., Isla Ortiz, David, Klat, Jaroslav, Obermair, Andreas, Landoni, Fabio, Rodriguez, Juliana, Manchanda, Ranjit, Kosťun, Jan, dos Reis, Ricardo, Meydanli, Mehmet M., Odetto, Diego, Laky, Rene, Zapardiel, Ignacio, Weinberger, Vit, Benešová, Klára, Borčinová, Martina, Pari, Darwin, Salehi, Sahar, Bizzarri, Nicolò, Akilli, Huseyin, Abu-Rustum, Nadeem R., Salcedo-Hernández, Rosa A., Javůrková, Veronika, Sláma, Jiří, van Lonkhuijzen, Luc R.C.W.

“…Current guidelines for surveillance strategy in cervical cancer are rigid, recommending the same strategy for all survivors. The aim of this study was to…”
Get full text

Stratification of lymph node metastases as macrometastases, micrometastases, or isolated tumor cells has no clinical implication in patients with cervical cancer: Subgroup analysis of the SCCAN project by Dostálek, Lukáš, Benešová, Klára, Klát, Jaroslav, Kim, Sarah H., Falconer, Henrik, Kostun, Jan, dos Reis, Ricardo, Zapardiel, Ignacio, Landoni, Fabio, Ortiz, David Isla, van Lonkhuijzen, Luc R.C.W., Lopez, Aldo, Odetto, Diego, Borčinová, Martina, Jarkovsky, Jiri, Salehi, Sahar, Němejcová, Kristýna, Bajsová, Sylva, Park, Kay J., Javůrková, Veronika, Abu-Rustum, Nadeem R., Dundr, Pavel, Cibula, David

“…In cervical cancer, presence of lymph-node macrometastases (MAC) is a major prognostic factor and an indication for adjuvant treatment. However, since clinical…”
Get full text

Survival associated with the use of sentinel lymph node in addition to lymphadenectomy in early-stage cervical cancer treated with surgery alone: A sub-analysis of the Surveillance in Cervical CANcer (SCCAN) collaborative study by Bizzarri, Nicolò, Querleu, Denis, Ramirez, Pedro T., Dostálek, Lukáš, van Lonkhuijzen, Luc RC W., Giannarelli, Diana, Lopez, Aldo, Salehi, Sahar, Ayhan, Ali, Kim, Sarah H., Isla Ortiz, David, Klat, Jaroslav, Landoni, Fabio, Pareja, Rene, Manchanda, Ranjit, Kosťun, Jan, Meydanli, Mehmet M., Odetto, Diego, Laky, Rene, Zapardiel, Ignacio, Weinberger, Vit, Dos Reis, Ricardo, Pedone Anchora, Luigi, Amaro, Karina, Akilli, Huseyin, Abu-Rustum, Nadeem R., Salcedo-Hernández, Rosa A., Javůrková, Veronika, Mom, Constantijne H., Falconer, Henrik, Scambia, Giovanni, Cibula, David

“…The aim of this study was to assess whether the use of sentinel lymph node (SLN) in addition to lymphadenectomy was associated with survival benefit in…”
Get full text

Survival associated with extent of radical hysterectomy in early-stage cervical cancer: a subanalysis of the Surveillance in Cervical CANcer (SCCAN) collaborative study by Bizzarri, Nicolò, Querleu, Denis, Dostálek, Lukáš, van Lonkhuijzen, Luc R.C.W., Giannarelli, Diana, Lopez, Aldo, Salehi, Sahar, Ayhan, Ali, Kim, Sarah H., Ortiz, David Isla, Klat, Jaroslav, Landoni, Fabio, Pareja, Rene, Manchanda, Ranjit, Kosťun, Jan, Ramirez, Pedro T., Meydanli, Mehmet M., Odetto, Diego, Laky, Rene, Zapardiel, Ignacio, Weinberger, Vit, Dos Reis, Ricardo, Pedone Anchora, Luigi, Amaro, Karina, Akilli, Huseyin, Abu-Rustum, Nadeem R., Salcedo-Hernández, Rosa A., Javůrková, Veronika, Mom, Constantijne H., Scambia, Giovanni, Falconer, Henrik, Cibula, David

“…International guidelines recommend tailoring the radicality of hysterectomy according to the known preoperative tumor characteristics in patients with…”
Get full text

The Role of HE4 in the Follow-Up of Advanced Ovarian, Fallopian Tube, and Primary Peritoneal Cancer—CEEGOG OX-01 Study by Presl, Jiri, Havelka, Pavel, Weinberger, Vit, Ovesna, Petra, Fekete, Peter, Fruhauf, Filip, Jedryka, Marcin, Bystricky, Branislav, Strojna, Aleksandra, Volodko, Nataliya, Matylevich, Olga, Herboltova, Petra, Blecharz, Pawel, Kalist, Vladimir, Ehrlichova, Lucie, Stranik, Petr, Masak, Ladislav, Poncova, Renata, Czekanski, Andrzej, Chaloupkova, Barbora, Koblizkova, Michaela, Smoligova, Vendula, Hrabalova, Marketa, Jaksicova, Alena, Linkesch, Peter, Viktora, Libor, Bouda, Jiri, Vlasak, Pavel, Kostun, Jan

“…Background: Ovarian, fallopian tube, and primary peritoneal cancers often share clinical characteristics and are typically diagnosed at advanced stages due to…”
Get full text

Importance of Preoperative Knowledge of the Biomarker HE4 in Early-stage Endometrial Cancer Regarding Surgical Management by Presl, Jiri, Ovesna, Petra, Novotny, Zdenek, Vlasak, Pavel, Bouda, Jiri, Kostun, Jan, Topolcan, Ondrej, Kucera, Radek, Bednarikova, Marketa, Weinberger, Vit

“…To analyze the utility of HE4 assessment in preoperative management of patients with early-stage endometrial cancer for stratification into low-risk and…”
Get full text

Association of Hospital Surgical Volume With Survival in Early-Stage Cervical Cancer Treated With Radical Hysterectomy by Bizzarri, Nicolò, Dostálek, Lukáš, van Lonkhuijzen, Luc R C W, Giannarelli, Diana, Lopez, Aldo, Falconer, Henrik, Querleu, Denis, Ayhan, Ali, Kim, Sarah H, Ortiz, David Isla, Klat, Jaroslav, Landoni, Fabio, Rodriguez, Juliana, Manchanda, Ranjit, Kosťun, Jan, Ramirez, Pedro T, Meydanli, Mehmet M, Odetto, Diego, Laky, Rene, Zapardiel, Ignacio, Weinberger, Vit, Dos Reis, Ricardo, Pedone Anchora, Luigi, Amaro, Karina, Salehi, Sahar, Akilli, Huseyin, Abu-Rustum, Nadeem R, Salcedo-Hernández, Rosa A, Javůrková, Veronika, Mom, Constantijne H, Scambia, Giovanni, Cibula, David

“…To evaluate the association of number of radical hysterectomies performed per year in each center with disease-free survival and overall survival. We conducted…”
Get full text

The annual recurrence risk model for tailored surveillance strategy in cervical cancer patients by Cibula, David, Dostálek, Lukáš, Jarkovsky, Jiri, Mom, Constantijne H., Lopez, Aldo, Falconer, Henrik, Fagotti, Anna, Ayhan, Ali, Kim, Sarah H., Ortiz, David Isla, Klat, Jaroslav, Obermair, Andreas, Landoni, Fabio, Rodriguez, Juliana, Manchanda, Ranjit, Kosťun, Jan, dos Reis, Ricardo, Meydanli, Mehmet Mutlu, Odetto, Diego, Laky, Rene, Zapardiel, Ignacio, Weinberger, Vit, Benešová, Klára, Borčinová, Martina, Pari, Darwin, Salehi, Sahar, Bizzarri, Nicolò, Akilli, Huseyin, Abu-Rustum, Nadeem R., Salcedo-Hernández, Rosa Angélica, Javůrková, Veronika, Sláma, Jiří, van Lonkhuijzen, Luc R.C.W.

Get full text

Inflammatory myofibroblastic tumor of the uterus - case report by Štiková, Zuzana, Ptáková, Nikola, Horáková, Markéta, Kosťun, Jan, Ondič, Ondrej

“…Inflammatory myofibroblastic tumor (IMT) of the uterus is rare but probably underdiagnosed tumor. It is usually benign but small fraction of cases may locally…”
Get more information