Search Results - "Kostikas, K"

Omalizumab for the treatment of allergic rhinitis: a systematic review and meta-analysis by Tsabouri, S, Ntritsos, G, Koskeridis, F, Evangelou, E, Olsson, P, Kostikas, K

“…Allergic rhinitis (AR), an IgE mediated inflammatory disease, significantly impacts quality of life of a considerable proportion of the general population…”
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Clinical, functional and inflammatory characteristics in patients with paucigranulocytic stable asthma: Comparison with different sputum phenotypes by Ntontsi, P., Loukides, S., Bakakos, P., Kostikas, K., Papatheodorou, G., Papathanassiou, E., Hillas, G., Koulouris, N., Papiris, S., Papaioannou, A. I.

“…Background According to induced sputum cell count, four different asthma phenotypes have been recognized (eosinophilic, neutrophilic, mixed and…”
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LABA/LAMA combinations versus LAMA monotherapy or LABA/ICS in COPD: a systematic review and meta-analysis by Rodrigo, Gustavo J, Price, David, Anzueto, Antonio, Singh, Dave, Altman, Pablo, Bader, Giovanni, Patalano, Francesco, Fogel, Robert, Kostikas, Konstantinos

“…Randomized controlled trials (RCTs) indicate that long-acting bronchodilator combinations, such as β -agonist (LABA)/muscarinic antagonist (LAMA), have…”
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Stratification of Patients with Chronic Obstructive Pulmonary Disease Using Volatile Organic Compounds by Exarchos, K P, Chronis, C, Lipirou, L, Sakkas, V, Kostikas, K

“…Chronic obstructive pulmonary disease (COPD) is a common disease that causes long-term disability and death. Its natural history is punctuated by acute…”
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Sputum and BAL Clara cell secretory protein and surfactant protein D levels in asthma by Emmanouil, P., Loukides, S., Kostikas, K., Papatheodorou, G., Papaporfyriou, A., Hillas, G., Vamvakaris, I., Triggidou, R., Katafigiotis, P., Kokkini, A., Papiris, S., Koulouris, N., Bakakos, P.

“…Clara cell secretory protein (CC16) is associated with Th2 modulation. Surfactant protein D (SPD) plays an important role in surfactant homeostasis and…”
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Clinical Impact and Healthcare Resource Utilization Associated with Early versus Late COPD Diagnosis in Patients from UK CPRD Database [Corrigendum] by Kostikas, Konstantinos, Price, David, Gutzwiller, Florian S., Jones, Bethan, Loefroth, Emil, Clemens, Andreas, Fogel, Robert, Jones, Rupert, Cao, Hui

“…Kostikas K, Price D, Gutzwiller FS, et al. Int J Chron Obstruct Pulmon Dis. 2020;15:1729–1738. On page 1730 in Patients and Methods, Study Design section, and…”
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Patient-Reported Outcomes (PROs) in COPD Clinical Trials: Trends and Gaps by Afroz, Nuzhat, Gutzwiller, Florian S, Mackay, Alex J, Naujoks, Christel, Patalano, Francesco, Kostikas, Konstantinos

“…Key characteristics of chronic obstructive pulmonary disease (COPD) that significantly affect health-related quality of life (HRQoL) include chest symptoms,…”
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The asthma-COPD overlap syndrome: do we really need another syndrome in the already complex matrix of airway disease? by Kostikas, Konstantinos, Clemens, Andreas, Patalano, Francesco

“…The term asthma-COPD overlap syndrome (ACOS) is one of multiple terms used to describe patients with characteristics of both COPD and asthma, representing ~20%…”
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The Perception of Physicians on Gender-Specific Differences in the Diagnosis of COPD: Results from a Questionnaire-Based Survey by Raherison-Semjen, Chantal, Mezzi, Karen, Kostikas, Konstantinos, Mackay, Alexander J, Singh, Dave

“…To evaluate the perception of physicians on gender-specific differences in the diagnosis of chronic obstructive pulmonary disease (COPD) using a qualitative…”
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Dual bronchodilation vs triple therapy in the "real-life" COPD DACCORD study by Buhl, Roland, Criée, Carl-Peter, Kardos, Peter, Vogelmeier, Claus F, Kostikas, Konstantinos, Lossi, Nadine S, Worth, Heinrich

“…No observational studies have evaluated the "real-world" effectiveness of dual bronchodilation comprising a long-acting β -agonist plus a long-acting…”
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Clinical Impact and Healthcare Resource Utilization Associated with Early versus Late COPD Diagnosis in Patients from UK CPRD Database by Kostikas, Konstantinos, Price, David, Gutzwiller, Florian S, Jones, Bethan, Loefroth, Emil, Clemens, Andreas, Fogel, Robert, Jones, Rupert, Cao, Hui

“…Purpose: Previous studies have shown that opportunities to diagnose chronic obstructive pulmonary disease (COPD) early are often missed in primary care. This…”
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Impact of COPD diagnosis timing on clinical and economic outcomes: the ARCTIC observational cohort study by Larsson, Kjell, Janson, Christer, Ställberg, Björn, Lisspers, Karin, Olsson, Petter, Kostikas, Konstantinos, Gruenberger, Jean-Bernard, Gutzwiller, Florian S, Uhde, Milica, Jorgensen, Leif, Johansson, Gunnar

“…Assess the clinical and economic consequences associated with an early versus late diagnosis in patients with COPD. In a retrospective, observational cohort…”
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The effect of indacaterol/glycopyrronium versus tiotropium or salmeterol/fluticasone on the prevention of clinically important deterioration in COPD by Anzueto, Antonio R, Vogelmeier, Claus F, Kostikas, Konstantinos, Mezzi, Karen, Fucile, Sebastian, Bader, Giovanni, Shen, Steven, Banerji, Donald, Fogel, Robert

“…Endpoints that evaluate deterioration rather than improvement of disease may have clinical utility in COPD. In this analysis, we compared the effects of…”
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Inhaled corticosteroid use by exacerbations and eosinophils: a real-world COPD population by Vestbo, Jørgen, Vogelmeier, Claus F, Small, Mark, Siddall, James, Fogel, Robert, Kostikas, Konstantinos

“…Blood eosinophils may predict response to inhaled corticosteroids (ICS) in chronic obstructive pulmonary disease (COPD) where ICS is recommended in patients at…”
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Exhaled breath condensate in patients with asthma: implications for application in clinical practice by Kostikas, K., Koutsokera, A., Papiris, S., Gourgoulianis, K. I., Loukides, S.

“…Summary Exhaled breath condensate (EBC) analysis, a rather appealing and promising method, can be used to evaluate conveniently and non‐invasively a wide range…”
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CONQUEST Quality Standards: For the Collaboration on Quality Improvement Initiative for Achieving Excellence in Standards of COPD Care by Pullen, Rachel, Miravitlles, Marc, Sharma, Anita, Singh, Dave, Martinez, Fernando, Hurst, John R, Alves, Luis, Dransfield, Mark, Chen, Rongchang, Muro, Shigeo, Winders, Tonya, Blango, Christopher, Muellerova, Hana, Trudo, Frank, Dorinsky, Paul, Alacqua, Marianna, Morris, Tamsin, Carter, Victoria, Couper, Amy, Jones, Rupert, Kostikas, Konstantinos, Murray, Ruth, Price, David B

“…Chronic obstructive pulmonary disease (COPD) are managed predominantly in primary care. However, key opportunities to optimize treatment are often not realized…”
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Sputum interleukin-13 as a biomarker for the evaluation of asthma control by Tsilogianni, Z., Hillas, G., Bakakos, P., Aggelakis, L., Konstantellou, E., Papaioannou, A. I., Papaporfyriou, A., Papiris, S., Koulouris, N., Loukides, S., Kostikas, K.

“…Summary Background Asthma control refers to the extent to which the manifestations of asthma have been reduced or eradicated by treatment. Interleukin‐13…”
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Increased levels of angiopoietins 1 and 2 in sputum supernatant in severe refractory asthma by Tseliou, E., Bakakos, P., Kostikas, K., Hillas, G., Mantzouranis, K., Emmanouil, P., Simoes, D., Alchanatis, M., Papiris, S., Loukides, S.

“…Background: Airway and vascular remodeling may play a prominent role in the clinical severity of severe refractory asthma (SRA). Angiopoietin‐1 (Ang‐1) is an…”
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A Real-World Study on the Day and Night-Time Symptoms Among Greek COPD Patients Who Recently Initiated Treatment with Dual Bronchodilation: The DANICO Study by Konstantinos, Kostikas, Dimakou, Katerina, Gourgoulianis, Konstantinos, Gaga, Mina, Papapetrou, Dimosthenis, Tsoukalas, Georgios, Chatziapostolou, Panagiotis, Antoniadis, Antonios, Meletis, Georgios, Evangelopoulou, Efstathia, Styliara, Panagiota, Karypidou, Ilektra, Gogali, Athena, Kalafatakis, Konstantinos, Tzanakis, Nikolaos

“…Purpose: The rationale of this study was to investigate the prevalence of daily and night symptoms and quality of sleep in Greek COPD patients as a means to…”
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Exhaled nitric oxide in asthma in adults: the end is the beginning? by Kostikas, K, Minas, M, Papaioannou, A I, Papiris, S, Dweik, R A

“…Approximately 20 years after the initial report of the measurement of exhaled nitric oxide (NO) in the exhaled air of humans, numerous publications have…”
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