Search Results - "Koster, Abraham J"

A unifying structural and functional model of the coronavirus replication organelle: Tracking down RNA synthesis by Snijder, Eric J, Limpens, Ronald W A L, de Wilde, Adriaan H, de Jong, Anja W M, Zevenhoven-Dobbe, Jessika C, Maier, Helena J, Faas, Frank F G A, Koster, Abraham J, Bárcena, Montserrat

“…Zoonotic coronavirus (CoV) infections, such as those responsible for the current severe acute respiratory syndrome-CoV 2 (SARS-CoV-2) pandemic, cause grave…”
Get full text

A molecular pore spans the double membrane of the coronavirus replication organelle by Wolff, Georg, Limpens, Ronald W. A. L., Zevenhoven-Dobbe, Jessika C., Laugks, Ulrike, Zheng, Shawn, de Jong, Anja W. M., Koning, Roman I., Agard, David A., Grünewald, Kay, Koster, Abraham J., Snijder, Eric J., Bárcena, Montserrat

“…Viral RNA exported from the coronavirus replication organelle is likely to be mediated by a crown-shaped molecular pore. A gateway to the cytosol Coronaviruses…”
Get full text

The Translocon Protein Sec61 Mediates Antigen Transport from Endosomes in the Cytosol for Cross-Presentation to CD8+ T Cells by Zehner, Matthias, Marschall, Andrea L., Bos, Erik, Schloetel, Jan-Gero, Kreer, Christoph, Fehrenschild, Dagmar, Limmer, Andreas, Ossendorp, Ferry, Lang, Thorsten, Koster, Abraham J., Dübel, Stefan, Burgdorf, Sven

“…The molecular mechanisms regulating antigen translocation into the cytosol for cross-presentation are under controversial debate, mainly because direct data is…”
Get full text

Expression and Cleavage of Middle East Respiratory Syndrome Coronavirus nsp3-4 Polyprotein Induce the Formation of Double-Membrane Vesicles That Mimic Those Associated with Coronaviral RNA Replication by Oudshoorn, Diede, Rijs, Kevin, Limpens, Ronald W A L, Groen, Kevin, Koster, Abraham J, Snijder, Eric J, Kikkert, Marjolein, Bárcena, Montserrat

“…Betacoronaviruses, such as Middle East respiratory syndrome coronavirus (MERS-CoV), are important pathogens causing potentially lethal infections in humans and…”
Get full text

Correlative cryo super-resolution light and electron microscopy on mammalian cells using fluorescent proteins by Tuijtel, Maarten W., Koster, Abraham J., Jakobs, Stefan, Faas, Frank G. A., Sharp, Thomas H.

“…Sample fixation by vitrification is critical for the optimal structural preservation of biomolecules and subsequent high-resolution imaging by cryo-correlative…”
Get full text

Asymmetric cryo-EM reconstruction of phage MS2 reveals genome structure in situ by Koning, Roman I, Gomez-Blanco, Josue, Akopjana, Inara, Vargas, Javier, Kazaks, Andris, Tars, Kaspars, Carazo, José María, Koster, Abraham J.

“…In single-stranded ribonucleic acid (RNA) viruses, virus capsid assembly and genome packaging are intertwined processes. Using cryo-electron microscopy and…”
Get full text

Complement Is Activated by IgG Hexamers Assembled at the Cell Surface by Diebolder, Christoph A., Beurskens, Frank J., de Jong, Rob N., Koning, Roman I., Strumane, Kristin, Lindorfer, Margaret A., Voorhorst, Marleen, Ugurlar, Deniz, Rosati, Sara, Heck, Albert J. R., van de Winkel, Jan G. J., Wilson, Ian A., Koster, Abraham J., Taylor, Ronald P., Saphire, Erica Ollmann, Burton, Dennis R., Schuurman, Janine, Gros, Piet, Parren, Paul W. H. I.

“…Complement activation by antibodies bound to pathogens, tumors, and self antigens is a critical feature of natural immune defense, a number of disease…”
Get full text

Renal Subcapsular Transplantation of PSC-Derived Kidney Organoids Induces Neo-vasculogenesis and Significant Glomerular and Tubular Maturation In Vivo by van den Berg, Cathelijne W., Ritsma, Laila, Avramut, M. Cristina, Wiersma, Loes E., van den Berg, Bernard M., Leuning, Daniëlle G., Lievers, Ellen, Koning, Marije, Vanslambrouck, Jessica M., Koster, Abraham J., Howden, Sara E., Takasato, Minoru, Little, Melissa H., Rabelink, Ton J.

“…Human pluripotent stem cell (hPSC)-derived kidney organoids may facilitate disease modeling and the generation of tissue for renal replacement. Long-term…”
Get full text

Influenza virus damages the alveolar barrier by disrupting epithelial cell tight junctions by Short, Kirsty R, Kasper, Jennifer, van der Aa, Stijn, Andeweg, Arno C, Zaaraoui-Boutahar, Fatiha, Goeijenbier, Marco, Richard, Mathilde, Herold, Susanne, Becker, Christin, Scott, Dana P, Limpens, Ronald W A L, Koster, Abraham J, Bárcena, Montserrat, Fouchier, Ron A M, Kirkpatrick, Charles James, Kuiken, Thijs

“…A major cause of respiratory failure during influenza A virus (IAV) infection is damage to the epithelial-endothelial barrier of the pulmonary alveolus. Damage…”
Get full text

Mind the gap: Micro-expansion joints drastically decrease the bending of FIB-milled cryo-lamellae by Wolff, Georg, Limpens, Ronald W.A.L., Zheng, Shawn, Snijder, Eric J., Agard, David A., Koster, Abraham J., Bárcena, Montserrat

“…[Display omitted] •Micro-expansion joints greatly increase the cryo-FIB-milling success rate.•These lateral gaps milled in the support prevent cryo-lamellae…”
Get full text

AreTomo: An integrated software package for automated marker-free, motion-corrected cryo-electron tomographic alignment and reconstruction by Zheng, Shawn, Wolff, Georg, Greenan, Garrett, Chen, Zhen, Faas, Frank G.A., Bárcena, Montserrat, Koster, Abraham J., Cheng, Yifan, Agard, David A.

“…[Display omitted] •AreTomo, a GPU accelerated software package, fully automates motion-corrected marker-free tomographic alignment and reconstruction.•AreTomo…”
Get full text

Cryoelectron Tomography of the NAIP5/NLRC4 Inflammasome: Implications for NLR Activation by Diebolder, Christoph A., Halff, Els F., Koster, Abraham J., Huizinga, Eric G., Koning, Roman I.

“…Inflammasomes are high molecular weight protein complexes that play a crucial role in innate immunity by activating caspase-1. Inflammasome formation is…”
Get full text

Heterogeneous MAC Initiator and Pore Structures in a Lipid Bilayer by Phase-Plate Cryo-electron Tomography by Sharp, Thomas H., Koster, Abraham J., Gros, Piet

“…Pore formation in membranes is important for mammalian immune defense against invading bacteria. Induced by complement activation, the membrane attack complex…”
Get full text

Atrasentan Reduces Albuminuria by Restoring the Glomerular Endothelial Glycocalyx Barrier in Diabetic Nephropathy by Boels, Margien G S, Avramut, M Cristina, Koudijs, Angela, Dane, Martijn J C, Lee, Dae Hyun, van der Vlag, Johan, Koster, Abraham J, van Zonneveld, Anton Jan, van Faassen, Ernst, Gröne, Hermann-Josef, van den Berg, Bernard M, Rabelink, Ton J

“…Atrasentan, a selective endothelin A receptor antagonist, has been shown to reduce albuminuria in type 2 diabetes. We previously showed that the structural…”
Get full text

SARS-coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulum by Knoops, Kèvin, Kikkert, Marjolein, Worm, Sjoerd H E van den, Zevenhoven-Dobbe, Jessika C, van der Meer, Yvonne, Koster, Abraham J, Mommaas, A Mieke, Snijder, Eric J

“…Positive-strand RNA viruses, a large group including human pathogens such as SARS-coronavirus (SARS-CoV), replicate in the cytoplasm of infected host cells…”
Get full text

Automated vitrification of cryo-EM samples with controllable sample thickness using suction and real-time optical inspection by Koning, Roman I., Vader, Hildo, van Nugteren, Martijn, Grocutt, Peter A., Yang, Wen, Renault, Ludovic L. R., Koster, Abraham J., Kamp, Arnold C. F., Schwertner, Michael

“…The speed and efficiency of data collection and image processing in cryo-electron microscopy have increased over the last decade. However, cryo specimen…”
Get full text

Ultrastructural Characterization of Arterivirus Replication Structures: Reshaping the Endoplasmic Reticulum To Accommodate Viral RNA Synthesis by KNOOPS, Kèvin, BARCENA, Montserrat, LIMPENS, Ronald W. A. L, KOSTER, Abraham J, MIEKE MOMMAAS, A, SNIJDER, Eric J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Cross-membranes orchestrate compartmentalization and morphogenesis in Streptomyces by Celler, Katherine, Koning, Roman I., Willemse, Joost, Koster, Abraham J., van Wezel, Gilles P.

“…Far from being simple unicellular entities, bacteria have complex social behaviour and organization, living in large populations, and some even as coherent,…”
Get full text

Origins of Enterovirus Replication Organelles Established by Whole-Cell Electron Microscopy by Melia, Charlotte E, Peddie, Christopher J, de Jong, Anja W M, Snijder, Eric J, Collinson, Lucy M, Koster, Abraham J, van der Schaar, Hilde M, van Kuppeveld, Frank J M, Bárcena, Montserrat

“…Enterovirus genome replication occurs at virus-induced structures derived from cellular membranes and lipids. However, the origin of these replication…”
Get full text

Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells by Schillemans, Maaike, Karampini, Ellie, van den Eshof, Bart L, Gangaev, Anastasia, Hofman, Menno, van Breevoort, Dorothee, Meems, Henriët, Janssen, Hans, Mulder, Aat A, Jost, Carolina R, Escher, Johanna C, Adam, Rüdiger, Carter, Tom, Koster, Abraham J, van den Biggelaar, Maartje, Voorberg, Jan, Bierings, Ruben

“…OBJECTIVE—Endothelial cells store VWF (von Willebrand factor) in rod-shaped secretory organelles, called Weibel-Palade bodies (WPBs). WPB exocytosis is…”
Get full text