Search Results - "Kosten, Tom"
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The concept of pharmacologic cocaine interception as a treatment for drug abuse
Published in Chemico-biological interactions (06-09-2010)“…Cocaine access to brain tissue and associated cocaine-induced behaviors are substantially reduced in rats and mice by significant plasma levels of an enzyme…”
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Anti-cocaine antibody and butyrylcholinesterase-derived cocaine hydrolase exert cooperative effects on cocaine pharmacokinetics and cocaine-induced locomotor activity in mice
Published in Chemico-biological interactions (25-03-2013)“…► Small amounts of cocaine hydrolase reduce cocaine levels in mouse plasma and brain. ► Anti-cocaine antibody can sequester cocaine in plasma. ► Antibody plus…”
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Journal Article