Search Results - "Kosten, Ilona"

MUTZ-3 derived Langerhans cells in human skin equivalents show differential migration and phenotypic plasticity after allergen or irritant exposure by Kosten, Ilona J., Spiekstra, Sander W., de Gruijl, Tanja D., Gibbs, Susan

“…After allergen or irritant exposure, Langerhans cells (LC) undergo phenotypic changes and exit the epidermis. In this study we describe the unique ability of…”
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Comparative phenotypic and functional analysis of migratory dendritic cell subsets from human oral mucosa and skin by Kosten, Ilona Jennifer, van de Ven, Rieneke, Thon, Maria, Gibbs, Susan, de Gruijl, Tanja D

“…Antigen exposure to oral mucosa is generally thought to lead to immune tolerance induction. However, very little is known about the subset composition and…”
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MUTZ-3 Langerhans cell maturation and CXCL12 independent migration in reconstructed human gingiva by Kosten, Ilona J, Spiekstra, Sander W, de Gruijl, Tanja D, Gibbs, Susan

“…Here we describe a reconstructed full thickness human oral mucosa (gingiva) equivalent with integrated Langerhans Cells (GE-LC) and use it to compare LC…”
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Gingiva Equivalents Secrete Negligible Amounts of Key Chemokines Involved in Langerhans Cell Migration Compared to Skin Equivalents by de Gruijl, Tanja D., Spiekstra, Sander W., Buskermolen, Jeroen K., Kosten, Ilona J., Gibbs, Susan

“…Both oral mucosa and skin have the capacity to maintain immune homeostasis or regulate immune responses upon environmental assault. Whereas much is known about…”
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Assessment of metal sensitizer potency with the reconstructed human epidermis IL-18 assay by Gibbs, Susan, Kosten, Ilona, Veldhuizen, Rosalien, Spiekstra, Sander, Corsini, Emanuela, Roggen, Erwin, Rustemeyer, Thomas, Feilzer, Albert J., Kleverlaan, Cees J.

“…•New EU Medical Device legislation (2017) calls for higher standards of safety for medical devices.•Using the RhE IL-18 assay, 15 metal salts used in medical…”
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Intradermal delivery of TLR agonists in a human explant skin model: preferential activation of migratory dendritic cells by polyribosinic-polyribocytidylic acid and peptidoglycans by Oosterhoff, Dinja, Heusinkveld, Moniek, Lougheed, Sinéad M, Kosten, Ilona, Lindstedt, Malin, Bruijns, Sven C M, van Es, Thomas, van Kooyk, Yvette, van der Burg, Sjoerd H, de Gruijl, Tanja D

“…TLR agonists are attractive candidate adjuvants for therapeutic cancer vaccines as they can induce a balanced humoral and T cell-mediated immune response. With…”
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The Human Glycoprotein Salivary Agglutinin Inhibits the Interaction of DC-SIGN and Langerin with Oral Micro-Organisms by Boks, Martine A., Gunput, Sabrina T.G., Kosten, Ilona, Gibbs, Susan, van Vliet, Sandra J., Ligtenberg, Antoon J.M., van Kooyk, Yvette

“…Salivary agglutinin (SAG), also known as gp340 or SALSA, is a glycoprotein encoded by the Deleted in Malignant Brain Tumours 1 gene and is abundantly present…”
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Generation, subsets and functions of inducible regulatory T cells by Kosten, Ilona J, Rustemeyer, Thomas

“…The idea of regulatory T cells (Tregs) lost its popularity during the 1980s and 1990s, since immunologists failed to elucidate how the innate regulation of…”
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