Search Results - "Kostanyan, I. A."

STAT1: A many-sided transcription factor by Kostanyan, I. A, Vonarshenko, A. V, Lipkin, V. M

“…The cell homeostasis is regulated by numerous signaling proteins. Their common task is to process extracellular signals by triggering cascades of intracellular…”
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HLDF-6 peptide affects behavioral reactions and organism functions dependent on androgen hormones in normal and castrated male mice by Rzhevsky, D.I., Zhokhov, S.S., Babichenko, I.I., Goleva, A.V., Goncharenko, E.N., Baizhumanov, A.A., Murashev, A.N., Lipkin, V.M., Kostanyan, I.A.

“…The hexapeptide Thr-Gly-Glu-Asn-His-Arg (HLDF-6), which was first identified as an active fragment of the human leukemia differentiation factor (HLDF)…”
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Intermediate amyloid oligomers of lysozyme: Is their cytotoxicity a particular case or general rule for amyloid? by Malisauskas, M, Darinskas, A, Zamotin, V V, Gharibyan, A, Kostanyan, I A, Morozova-Roche, L A

“…In the current study we investigated the molecular mechanisms of cytotoxicity of amyloid oligomers of horse milk lysozyme. We have shown that lysozyme forms…”
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Granulocyte differentiation inducer, hexapeptide HLDF-6, decreases cytotoxic effect of tumor necrosis factor on HL-60 cell line by Gibanova, N V, Rakitina, T V, Lipkin, V M, Kostanyan, I A

“…The effect of hexapeptide HLDF-6, the granulocytic differentiation inducer, on the tumor necrosis factor alpha (TNF-alpha)-induced differentiation and…”
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Antitumor and Immunomodulating Effects of a Fragment of HL-60 Cell Differentiation Factor in Mice with Lewis Pulmonary Carcinoma by Sysoeva, G. M, Fadina, V. A, Danilenko, E. D, Samukov, V. V, Kostanyan, I. A, Masycheva, V. I

“…A six-member HLDF6 peptide, fragment of HL-60 cell differentiation factor, exhibited antimetastatic and immunomodulating effects…”
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Amyloidogenic properties of the artificial protein albebetin and its biologically active derivatives. The role of electrostatic interactions in fibril formation by Lavrikova, M A, Zamotin, V V, Malisauskas, M, Chertkova, R V, Kostanyan, I A, Dolgikh, D A, Kirpichnikov, M P, Morozova-Roche, L A

“…The artificial protein albebetin (ABB) and its derivatives containing biologically active fragments of natural proteins form fibrils at physiological pH. The…”
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Neuroprotective effect of the hexapeptide HLDF-6 on rat hippocampal neurons on the in vivo and in vitro models of alzheimer’s disease by Kostanyan, I. A., Zhokhov, S. S., Storozheva, Z. I., Proshin, A. T., Surina, E. A., Babichenko, I. I., Sherstnev, V. V., Lipkin, V. M.

“…The neuroprotective effect of Thr-Gly-Glu-Asn-His-Arg hexapeptide (HLDF-6), a biologically active fragment of the differentiation factor of human leukemia…”
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Experimental model of hemorrhagic stroke: rabbit immunization with HL-60 promyelocytic cell differentiation factor by Gapon, M V, Dranitsyna, S M, Minkevich, N I, Gruden', M A, Babichenko, I I, Kostanyan, I A

“…Rabbits immunized with synthetic HLDF differentiation factor developed hemorrhagic stroke with thrombosis of small cerebral vessels and destruction of vascular…”
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Different mechanisms of protective and differentiative activities of homological peptides TGENHR and TQVEHR by Zhokhov, S S, Kostanyan, I A, Gibanova, N V, Surina, E A, Rodionov, I L, Storozheva, Z I, Proshin, A T, Babichenko, I I, Lipkin, V M

“…Previously we identified a six-membered fragment 354TQVEHR359 of the C-terminal part of the PEDF (Pigment Epithelium-Derived Factor) differentiation factor…”
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Synthesis and structure-function study of artificial nucleases on the basis of hemin conjugates with peptide fragments of cell differentiation factor HLDF by Zheltukhina, G. A., Lobanova, T. N., Nebolsin, V. E., Gallyamov, M. O., Dranitsyna, S. M., Kostanyan, I. A.

“…A series of octa-hexapeptide fragments of HLDF and their conjugates with hemin were obtained by solid phase peptide synthesis. A relationship between the…”
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Study of interaction between l-glutamate and human blood lymphocytes by Kostanyan, I.A, Merkulova, M.I, Navolotskaya, E.V, Nurieva, R.I

“…The presence of specific glutamate receptors on T lymphocytes separated from normal human blood was investigated. Upon study of T lymphocytes interaction with…”
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PEDF - A Noninhibitory Serpin with Neurotrophic Activity by Minkevich, N I, Lipkin, V M, Kostanyan, I A

“…The pigment epithelium-derived factor (PEDF) is a glycoprotein with a molecular weight of 50 kDa belonging to the noninhibitory serpin family. It regulates…”
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Soluble Fas antigen in the serum of patients with colon cancer by Kushlinskii, N E, Britvin, T A, Abbasova, S G, Perevoshchikov, A G, Prorokov, V V, Kostanyan, I A, Knysh, V I, Lipkin, V M

“…Serum concentration of soluble Fas antigen (sFas) was measured in 60 normal subjects and 33 patients with colon cancer. The incidence of sFas detection and its…”
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Novel protein haponin regulates cellular response to oxidative stress by Smirnova, E. V., Rakitina, T. V., Bogatova, O. V., Ivanova, D. L., Vorobyeva, E. E., Lipkin, A. V., Kostanyan, I. A., Lipkin, V. M.

“…A novel protein haponin (NP_115701.2) has been isolated and characterized earlier in the laboratory of hormonal regulation of proteins. The role of this…”
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Postischemic administration of HLDF-6 peptide ameliorates cognitive dysfunction and brain damage induced by chronic cerebral Ischemia in rats by Kostanyan, I. A., Storozheva, Z. I., Semenova, N. A., Lipkin, V. M.

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HLDF-6 peptide relieves symptoms of abstinence syndrome during experimental opium abuse by Litvinova, S V, Kalyuzhnyi, A L, Aristova, V V, Shulgovskii, V V, Kostanyan, I A, Terebelina, N N, Panchenko, L F

“…Experiments were performed on rats with opium abuse induced by chronic administration of morphine in increasing doses. We studied the effect of HLDF-6 peptide…”
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ANTIBODIES TO LEUKEMIA DIFFERENTIATION FACTOR (HLDF) IN PATIENTS WITH GASTROINTESTINAL CANCER by Autenshlus, A. I., Sosnina, A. V., Mikhailiva, E. S., Lykov, A. P., Tumanov, Yu. V., Danilanko, E. D., Samukov, V. S., Kostanyan, I. A., Morozov, D. V., Cherenkova, M. M., Thvan, L. .A., Varaksin, N. A.

“…Antibodies to leukemia differentiation factor (HLDF) in patients with gastrointestinal cancer Abstract. Patients with gastric cancer exhibit higher levels of…”
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Use of HLDF-6 peptide for correction of disturbances in the endogenous opioid system in offspring of morphine-tolerant animals by Litvinova, S V, Kostanyan, I A, Aristova, V V, Kalyuzhnyi, A L, Shul'govskii, V V, Terebilina, N N, Panchenko, L F

“…We studied the effect of bioactive peptide HLDF-6 on functional activity of the endogenous antinociceptive system in the offspring of morphine-tolerant…”
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Haponin (EIF1AD) interacts with glyceraldehyde 3-phosphate dehydrohenase in the CHO-K1 cell line by Rakitina, T. V, Bogatova, O. V, Smirnova, E. V, Pozdeev, V. I, Kostanyan, I. A, Lipkin, V. M

“…Haponin (HLDF-alike protein) was previously identified from the human promyelocytic leukemia HL-60 cell line. For the functional study of this protein, we…”
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Leptin and apoptosis inhibitor soluble Fas antigen in the serum of patients with osteosarcoma and neuroectodermal bone tumors by Kushlinskii, N E, Solov'ev, Y N, Babkina, I V, Abbasova, S G, Kostanyan, I A, Lipkin, V M, Trapeznikov, N N

“…Serum contents of leptin and soluble Fas antigen were measured in 28 patients with osteosarcoma, 7 with neuroectodermal bone tumors, and 17 healthy subjects…”
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