Search Results - "Kostanian, I A"

Amyloid-like fibrils forming and fibroblasts destruction in Tenon's capsule in progressive myopia as a result of pigment epithelium derived factor resistance to restricted proteolysis by Minkevich, N I, Rakitina, T V, Bogachuk, A P, Radchenko, V V, Surina, E A, Morozova-Roche, L A, Yanamandra, K, Iomdina, E N, Babichenko, I I, Kostanian, I A, Lipkin, V M

“…We have shown previously the presence of full length (50 kD) and truncated proteolytic form (45 kD) of pigment epithelium derived factor (PEDF) in the eye…”
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Investigation of antitumor activity of the hexamer fraction of HLDF-6 peptide as a differentiation factor in hemoblastoma-bearing mice by Danilenko, E D, Sysoeva, G M, Ustimenko, S Iu, Samukov, V V, Kostanian, I A, Masycheva, V I

“…A study of antitumor properties of HLDF-6 was carried out in DBA/2 mice with transplantable ascites lympholeukemia P-388 as well as in tumor cell culture…”
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Synthesis and structure-function study of artificial nucleases on the basis of hemin conjugates with peptide fragments of cell differentiation factor HLDF by Zheltukhina, G A, Lobanova, T N, Nebol'sin, V E, Galliamov, M O, Dranitsyna, S M, Kostanian, I A

“…A series of octa-hexapeptide fragments of HLDF and their conjugates with hemin were obtained by solid phase peptide synthesis. A relationship between the…”
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Neuroprotective effect of the hexapeptide HLDF-6 on neurons of rat hippocampus on the model of Alzheimer's disease in vivo and in vitro by Kostanian, I A, Zhokhov, S S, Storozheva, Z I, Proshin, A T, Surina, E A, Babichenko, I I, Sherstnev, V V, Lipkin, V M

“…The neuroprotective effect of Thr-Gly-Glu-Asn-His-Arg hexapeptide (HLDF-6), a biologically active fragment of the differentiation factor of human leukemia…”
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STAT1: a many-sided transcription factor by Kostanian, I A, Vonarshenko, A V, Lipkin, V M

“…Cell homeostasis is regulated by numerous signaling proteins. Their main task is to process extracellular signals and activate the intracellular cascades of…”
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Haponin (eIF1AD) interacts with glyceraldehyde 3-phosphate dehydrogenase in the CHO-K1 cell line by Rakitina, T V, Bogatova, O V, Smirnova, E V, Pozdeev, V I, Kostanian, I A, Lipkin, V M

“…Haponin (HLDF-alike protein) was previously identified from the human promyelocytic leukemia HL-60 cell line. For the functional study of this protein, we…”
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Antitumor properties of a liposomal form of a differentiation factor HLDF fragment in cultured cells by Bateneva, A V, Babenko, O A, Danilenko, E D, Poryvaev, V D, Karpyshev, N N, Goncharova, E P, Kostanian, I A, Masycheva, V I

“…Cytotoxic properties of a liposomal form of the HLDF6 hexapeptide, representing an HL-60 cell differentiation factor fragment, have been studied on a murine…”
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The proapoptotic factor HLDF in the normal, hyperplastic and neoplastic endometrium by Koviazin, V A, Shchelokova, E E, Kostanian, I A, Dranitsyna, S M, Frolova, I I, Babichenko, I I

“…Antibodies to the factor HLDF are shown to be specific markers of apoptosis and permit the estimation of the rate of programmed cell death in the course of a…”
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Identification and expression of haponin, a new protein from HL-60 cells by Vonarshenko, A V, Radchenko, V V, Gapon, M V, Rodionov, I L, Babichenko, I I, Kakuev, D L, Artamonov, I D, Garkovenko, A V, D'iachkova, L G, Lipkin, V M, Kostanian, I A

“…We found a new protein haponin (an HLDF-alike protein) in promyelocyte HL-60 cells that is immunoreactive to polyclonal antibodies against HLDFbeta…”
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L-Glutamic acid modulates the cytotoxic effect of tumor necrosis factor in the HL-60 cell line by Gibanova, N V, Rakitina, T V, Zhokhov, S S, Pustoshilova, N M, Lipkin, V M, Kostanian, I A

“…L-Glutamic acid was shown to increase the stability of cells of the HL-60 line of human promyelocyte leukemia to the cytotoxic action of tumor necrosis factor…”
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Precursors of HLDF differentiation factor and ribosomal protein RPS21 have a common N-terminal sequence by Smirnova, E V, Garkovenko, A V, Rakitina, T V, Berezhnoĭ, S N, Astapova, M V, Surina, E A, Babichenko, I I, Kostanian, I A, Lipkin, V M

“…The mature differentiation factor HLDF, isolated from culture fluid, comprises 54 aa, whereas the open reading frame of mRNA encodes a 97-aa protein. We…”
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Nuclease activity of human interleukin-10 by Dranitsyna, S M, Kostanian, I A, Astapova, M V, Surina, E A, Lipkin, V M

“…The nuclease activity of human interleukin-10, an immunosuppressive cytokine, was predicted on the basis of structural homology between the 97-105 sequence of…”
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An artificial protein, possessing biological activity of HL-60 human promyelocytic leukemia differentiation factor by Chertkova, R V, Kostanian, I A, Astapova, M V, Surina, E A, Dolgikh, D A, Kirpichnikov, M P

“…The ABB-df artificial protein was prepared by inserting the TGENHR biologically active peptide corresponding to the 41-46 sequence of the differentiation…”
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Cloning and characterization of the human ribosomal protein S21 gene by Smirnova, E V, Rakitina, T V, Evtodienko, A Iu, Kostanian, I A, Lipkin, V M

“…A full-size functional gene encoding the human ribosomal protein S21 was cloned and characterized. Its nucleotide sequence, exon-intron organization, and…”
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Synthetic peptides -- analogs of biologically active fragment of the differentiation factor from HL-60 cells show radioprotective and adaptogenic activities by Goncharenko, E N, Deev, L I, Kostanian, I A, Astapova, M V, Akhalaia, M Ia, Kudriashova, N Iu, Surina, E A

“…It was shown that the addition of synthetic six-membered peptide (HLDF-6) and its Tyr-analog (HLDF-Y) to cultural medium significantly increased the survival…”
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Effect of homologous peptides of differentiation factors HLDF and PEDF on preimplantation development of mice in vitro by Sakharova, N Iu, Kostanian, I A, Lepikhova, T N, Lepikhov, K A, Malashenko, A M, Navolotskaia, E V, Tombran-Tink, J, Lipkin, V M

“…We studied the effect of synthetic peptides PEDF-6 and HLDF-6 on preimplantation development of mouse embryos in vitro. PEDF-6 peptide corresponds to fragment…”
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Protein HLDF and antibodies to it as molecular pathogenetic factors and new markers of acute cerebral blood circulation disturbances by Sherstnev, V V, Skvortsova, V I, Gruden', M A, Shirokov, E A, Denshchuk, I S, Iurasov, V V, Elistratova, E I, Iakovleva, N E, Shetova, I M, Kostanian, I A, Gubskaia, O B

“…Clinic-experimental complex investigation and ELISA determination of protein HLDF as also primary antibodies (Abs) to HLDF values in blood and cerebro-spinal…”
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Expression of the apoptosis inhibitor soluble Fas antigen in patients with malignant and benign bone neoplasms by Kushlinskiĭ, N E, Solov'ev, Iu N, Babkina, I V, Abbasova, S G, Kostanian, I A, Lipkin, V M, Trapeznikov, N N

“…This paper presents results of comparative enzyme immunoassay of soluble serum Fas antigen (sFas) in 98 patients with benign and malignant bone tumors, 15…”
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L-glutamic acid--a modulator of the physiological status of myeloid series blood cells by Astapova, M V, Lipkin, V M, Arkhipova, M V, Andreeva, S G, Dranitsyna, S M, Merkulova, M I, Nurieva, R I, Navolotskaia, E V, Kostanian, I A

“…The effects of L-glutamic acid on the differentiation of HL-60 and K-562 cell lines and on the expression level of mRNAs encoding IL-1 beta, IL-6, and TNF…”
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Biological role of a neurotrophic factor fragment from pigment epithelium: structure-functional homology with a differentiation factor for the HL-60 cell line by Kostanian, I A, Zhokhov, S S, Astapova, M V, Dranitsyna, S M, Bogachuk, A P, Baĭdakova, L K, Rodionov, I L, Baskin, I I, Golubeva, O N, Tombran-Tink, J, Lipkin, V M

“…It was shown that the full-size neurotrophic factor from pigment epithelium (PEDF) induces the cell differentiation of the human promyelocyte leukemia cell…”
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