Search Results - "Kostakis, Panagiota"

Long-term imatinib therapy promotes bone formation in CML patients by Fitter, Stephen, Dewar, Andrea L., Kostakis, Panagiota, To, L. Bik, Hughes, Timothy P., Roberts, Marion M., Lynch, Kevin, Vernon-Roberts, Barrie, Zannettino, Andrew C.W.

“…Imatinib inhibits tyrosine kinases important in osteoclast (c-Fms) and osteoblast (platelet-derived growth factor receptor [PDGF-R], c-Abl) function,…”
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RANK Expression as a Cell Surface Marker of Human Osteoclast Precursors in Peripheral Blood, Bone Marrow, and Giant Cell Tumors of Bone by Atkins, Gerald J, Kostakis, Panagiota, Vincent, Cristina, Farrugia, Amanda N, Houchins, Jeffrey P, Findlay, David M, Evdokiou, Andreas, Zannettino, Andrew CW

“…RANK expression in vivo on hematopoietic subsets including pre‐osteoclasts, identified by monoclonal antibodies, has not been described. We describe the…”
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RANKL Expression Is Related to the Differentiation State of Human Osteoblasts by Atkins, Gerald J, Kostakis, Panagiota, Pan, Beiqing, Farrugia, Amanda, Gronthos, Stan, Evdokiou, Andreas, Harrison, Kate, Findlay, David M, Zannettino, Andrew Cw

“…Human osteoblast phenotypes that support osteoclast differentiation and bone formation are not well characterized. Osteoblast differentiation markers were…”
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Neurocognitive and behavioural performance of healthy volunteers receiving an increasing analgesic-range infusion of ketamine by Hayley, Amie, Green, Maja, Downey, Luke, Keane, Michael, Kostakis, Panagiota, Shehabi, Yahya

“…Background The acute and delayed effect of analgesic-range doses of ketamine on neurocognitive and behavioural outcomes is understudied. Using a non-controlled…”
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The acute and residual effects of escalating, analgesic-range doses of ketamine on driving performance: A simulator study by Hayley, Amie C., Green, Maja, Downey, Luke A., Stough, Con K.K., Keane, Michael, Shiferaw, Brook, Kostakis, Panagiota, Shehabi, Yahya

“…Ketamine hydrochloride elicits potent psychotomimetic and neurobehavioural effects which make it incompatible with driving; however, the direct effect on…”
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Accuracy of the Securetec DrugWipe 6s Ketamine device in detecting acute and residual salivary ketamine following a stepwise intravenous treatment protocol by Hayley, Amie C., Green, Maja, Keane, Michael, Kostakis, Panagiota, Shehabi, Yahya, Stough, Con K. K., Downey, Luke A.

“…To evaluate the sensitivity of the Securetec DrugWipe 6 S Ketamine device in detecting salivary ketamine, we administered three fixed, increasing…”
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Receptor activator of nuclear factor-κB ligand expression by human myeloma cells mediates osteoclast formation in vitro and correlates with bone destruction in vivo by FARRUGIA, Amanda N, ATKINS, Gerald J, TO, L. Bik, BEIQING PAN, HORVATH, Noemi, KOSTAKIS, Panagiota, FINDLAY, David M, BARDY, Peter, ZANNETTINO, Andrew C. W

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Human trabecular bone-derived osteoblasts support human osteoclast formation in vitro in a defined, serum-free medium by Atkins, Gerald J., Kostakis, Panagiota, Welldon, Katie J., Vincent, Cristina, Findlay, David M., Zannettino, Andrew C.W.

“…While it has been assumed that osteoblasts in the human support osteoclast formation, in vitro evidence of this is currently lacking. We tested the ability of…”
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Long-term imatinib therapy promotes bone formation in CML patients. Commentary by MATHEW, Paul, FITTER, Stephen, DEWAR, Andrea L, KOSTAKIS, Panagiota, TO, L. Bik, HUGHES, Timothy P, ROBERTS, Marion M, LYNCH, Kevin, VERNON-ROBERTS, Barrie, ZANNETTINO, Andrew C. W

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Isolation of a Human Homolog of Osteoclast Inhibitory Lectin That Inhibits the Formation and Function of Osteoclasts by Hu, Yun Shan, Zhou, Hong, Myers, Damian, Quinn, Julian MW, Atkins, Gerald J, Ly, Chi, Gange, Christine, Kartsogiannis, Vicky, Elliott, Jan, Kostakis, Panagiota, Zannettino, Andrew CW, Cromer, Brett, Mckinstry, William J, Findlay, David M, Gillespie, Matthew T, Ng, Kong Wah

“…Osteoclast inhibitory lectin (OCIL) is a newly recognized inhibitor of osteoclast formation. We identified a human homolog of OCIL and its gene, determined its…”
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Receptor activator of nuclear factor-kappaB ligand expression by human myeloma cells mediates osteoclast formation in vitro and correlates with bone destruction in vivo by Farrugia, Amanda N, Atkins, Gerald J, To, L Bik, Pan, Beiqing, Horvath, Noemi, Kostakis, Panagiota, Findlay, David M, Bardy, Peter, Zannettino, Andrew C W

“…Multiple myeloma (MM) is an incurable B-cell malignancy able to mediate massive destruction of the axial skeleton. The aim of this study was to examine the…”
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