Search Results - "Kost, N V"

Effect of Neurotropic and Immunotropic Drugs on Leukocyte Elastase Activity In Vitro by Zozulya, S. A., Sokolov, O. Yu, Kost, N. V.

“…Leukocyte elastase is a marker of inflammation. Previously, a relationship was found between the severity of mental disorders in patients and elastase-like…”
Get full text

Effects of Semax on the Default Mode Network of the Brain by Lebedeva, I. S., Panikratova, Ya. R., Sokolov, O. Yu, Kupriyanov, D. A., Rumshiskaya, A. D., Kost, N. V., Myasoedov, N. F.

“…The effects of nootropic drug Semax on the neuronal network of the brain were studied by the resting state functional magnetic-resonance imaging (resting state…”
Get full text

Neurotropic peptide HLDF-6-amide reduces age-related decline in sexual activity in old male rats by Sokolov, O.Yu, Prokhorova, T.A., Tereshkina, E.B., Zozulya, S.A., Simonov, A.N., Kost, N.V., Dadayan, A.K., Bogachouk, A.P., Zolotarev, Yu.A

“…Aging is associated with a decline in the erectile capacity and sexual motivation. Emerging new therapy for the treatment of these age-related pathologies in…”
Get full text

Haloperidol Reduces the Activity of Complement and Induces the Anti-Inflammatory Transformation of Peritoneal Macrophages in Rats by Cheremnykh, E. G., Ivanov, P. A., Sokolov, Oleg Yu, Prokhorova, T. A., Tereshkina, E. B., Baymeeva, N. V., Miroshnichenko, I. I., Kost, N. V.

“…It is known that psychotropic substances affect the immune system. Unfortunately, chronic antipsychotic administration causes side toxicological effects,…”
Get full text

Assessment of the Cytotoxicity of Peptide Modifications of Doxorubicin on Tetrahymena pyriformis by Pozdnyakova, A. N., Cheremnykh, E. G., Sokolov, O. Yu, Kost, N. V., Shevchenko, K. V., Shevchenko, V. P., Nagaev, I. Yu, Andreeva, L. A., Myasoedov, N. F.

“…The cytotoxicity of doxorubicin (Dox) and its peptide modifications Z-Gly-Pro-Dox and Boc-Gly-Pro-Dox were studied. Tetrahymena pyriformis was used as a test…”
Get full text

Functional Connectomic Approach to Studying Selank and Semax Effects by Panikratova, Ya. R., Lebedeva, I. S., Sokolov, O. Yu, Rumshiskaya, A. D., Kupriyanov, D. A., Kost, N. V., Myasoedov, N. F.

“…The present study was aimed at the assessment of effects of anxiolytic Selank and nootropic Semax on the whole-brain resting-state functional connectivity (FC)…”
Get full text

Dipeptidylpeptidase 4 (DPP4, CD26) activity in the blood serum of term and preterm neonates with cerebral ischemia by Yakovleva, A.A, Zolotov, N.N, Sokolov, O.Yu, Kost, N.V, Kolyasnikova, K.N, Micheeva, I.G

“…Abstract Background To investigate the mechanisms of inflammation in neonates after cerebral ischemia (CI), we evaluated the DPP4 activity in their blood sera…”
Get full text

Reactions between beta-casomorphins-7 and 5-HT2-serotonin receptors by Sokolov, O Yu, Pryanikova, N A, Kost, N V, Zolotarev, Yu A, Ryukert, E N, Zozulya, A A

“…Radioreceptor analysis showed that human beta-casomorphin-7 displaced 3H-spiperone from 5-HT2-serotonin receptors of the rat cerebral frontal cortex: EC50 8…”
Get full text

Neurotensin-Like Peptides as Potential Antipsychotics: Modulation of the Serotonin System by Kost, N. V., Meshavkin, V. K., Khashaba, E. Yu, Sokolov, O. Yu, Voevodina, M. E., Zolotarev, Yu. A., Andreeva, L. A., Myasoedov, N. F.

“…Neurotensin-like peptides acting as functional antagonists of serotonin receptors were revealed in the head-shaking test on mice. The neurotensin-like peptides…”
Get full text

The Qualitative Analysis of the Amide Derivative of HLDF-6 Peptide and Its Metabolites with the Use of Tritium- and Deuterium-Labeled Derivatives by Zolotarev, A, Dadayan, A K, Kost, N V, Voevodina, M E, Sokolov, O Y, Kozik, V S, Shram, S I, Azev, V N, Bocharov, E V, Bogachouk, A P, Lipkin, V M, Myasoedov, N F

“…The goal of the study was to elaborate the pharmacokinetics methods of the amide derivative of peptide HLDF-6 (TGENHR-NH2) and its range of nootropic and…”
Get more information

Optimization of the treatment of anxiety disorders with selank by Medvedev, V E, Tereshchenko, O N, Kost, N V, Ter-Israelyan, A Yu, Gushanskaya, E V, Chobanu, I K, Sokolov, O Yu, Myasoedov, N F

“…To compare the efficacy and tolerability of monotherapy with phenazepam to complex treatment with the peptide preparation selank and phenazepam in patients…”
Get more information

The influence of oligopeptides on spontaneous carcinogenesis in mice by Meshavkin, V. K., Kost, N. V., Sokolov, O. Yu, Andreeva, L. A., Myasoedov, N. F.

Get full text

Half-life of leu-enkephalin in the serum of infants of the first year of life on different types of feeding: relationship with temperament by Sokolov, O Yu, Kurasova, O B, Kost, N V, Gabaeva, M V, Korneeva, E V, Mikheeva, I G, Zozulya, A A

“…The half-life of leu-enkephalin in the serum of infants aged under 1 year is significantly shorter than in adults. In girls leu-enkephalin half-life is…”
Get full text

Change in the spectral characteristics of olanzapine upon protonation by Shevchenko, V. P, Nagaev, I. Yu, Kost, N. V, Ivanov, I. A, Myasoedov, N. F

Get full text

Effects of Selank on behavioral reactions and activities of plasma enkephalin-degrading enzymes in mice with different phenotypes of emotional and stress reactions by Sokolov, O Yu, Meshavkin, V K, Kost, N V, Zozulya, A A

“…Comparative study of plasma activities of enkephalin-degrading enzymes in mice with different phenotypes of emotional and stress reactions revealed significant…”
Get full text

Effects of Pro-Gly-Pro Tripeptide on the Dopamine System by Meshavkin, V. K., Batishcheva, E. Yu, Kost, N. V., Sokolov, O. Yu, Trufanova, A. V., Samonina, G. E.

“…Tripeptide Pro-Gly-Pro interacted with dopamine receptors in vitro and reduced behavioral manifestations of apomorphine-induced hyperfunction of the dopamine…”
Get full text

The inhibitory effect of Selank on enkephalin-degrading enzymes as a possible mechanism of its anxiolytic activity by Zozulya, A A, Kost, N V, Yu Sokolov, O, Gabaeva, M V, Grivennikov, I A, Andreeva, L N, Zolotarev, Y A, Ivanov, S V, Andryushchenko, A V, Myasoedov, N F, Smulevich, A B

“…Examination of patients with various forms of anxiety and phobic disorders (according to DSM-4 criteria) demonstrated a considerable shortening of enkephalin…”
Get full text

Naloxone-induced suppression of the behavioral manifestation of serotoninergic system hyperactivation by beta-casomorphins-7 in mice by Zozulia, A A, Meshavkin, V K, Sokolov, O Iu, Kost, N V

“…The effect of human and bovine beta-casomorphins-7 on the behavior of mice under conditions of 5-hydroxytryptophan (5-HT) induced hyperactivation of the…”
Get more information

Leu-Enkephalin Generally Labeled with Tritium in Studying the Selank Inhibiting Effect on the Enkephalin-Degrading Enzymes of Human Blood Plasma by Zolotarev, Yu. A., Sokolov, O. Yu, Kost, N. V., Vaskovsky, B. V., Myasoedov, N. F., Zozulya, A. A.

Get full text

Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia by Zozulia, A A, Neznamov, G G, Siuniakov, T S, Kost, N V, Gabaeva, M V, Sokolov, O Iu, Serebriakova, E V, Siranchieva, O A, Andriushenko, A V, Telesheva, E S, Siuniakov, S A, Smulevich, A B, Miasoedov, N F, Seredenin, S B

“…Sixty-two patients with generalized anxiety disorder (GAD) and neurasthenia were studied. The effect of selank (30 patients) was compared to that of medazepam…”
Get more information