Search Results - "Kossida, S"

State-of-the-art technology in modern computer-aided drug design by Dalkas, Georgios A, Vlachakis, Dimitrios, Tsagkrasoulis, Dimosthenis, Kastania, Anastasia, Kossida, Sophia

“…The quest for small drug-like compounds that selectively inhibit the function of biological targets has always been a major focus in the pharmaceutical…”
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Lysyl-tRNA synthetase produces diadenosine tetraphosphate to curb STING-dependent inflammation by Guerra, J, Valadao, A-L, Vlachakis, D, Polak, K, Vila, I K, Taffoni, C, Prabakaran, T, Marriott, A S, Kaczmarek, R, Houel, A, Auzemery, B, Déjardin, S, Boudinot, P, Nawrot, B, Jones, N J, Paludan, S R, Kossida, S, Langevin, C, Laguette, N

“…Inflammation is an essential part of immunity against pathogens and tumors but can promote disease if not tightly regulated. Self and non-self-nucleic acids…”
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Comparative transcriptome profiles in HIV-infected persons according to their clinical phenotype by C.K. Psomas, D.G. Kontopoulos, S. Kinloch-De Loës, S. Kossida, M.L. Gougeon

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Identification of phylogenetically conserved enhancer elements implicated in pancreas development in the WISP1 and CTGF orthologs by Kapasa, M., Serafimidis, I., Gavalas, A., Kossida, S.

“…WISP1 and CTGF are members of the CCN family of growth factors encoding extracellular matrix proteins participating in several developmental and tumorigenic…”
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The FlyBase Database of the Drosophila Genome Projects and community literature by FlyBase Consortium, The

“…The flybase drosophila genetics database and the public interfaces of the berkeley drosophila genome project (bdgp) and european drosophila genome project…”
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POS-03.62: Characterization of novel candidate biomarkers for prostate cancer using quantitative proteomic profiling by Tyritzis, S, Garbis, S, Pavlakis, K, Vourekas, S, Roumeliotis, T, Zerefos, P, Vlahou, A, Kossida, S, Diaz, J, Constantinides, C

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Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: the 2022 update of the recommendations by ERIC, the European Research Initiative on CLL by Agathangelidis, Andreas, Chatzidimitriou, Anastasia, Chatzikonstantinou, Thomas, Tresoldi, Cristina, Davis, Zadie, Giudicelli, Véronique, Kossida, Sofia, Belessi, Chrysoula, Rosenquist, Richard, Ghia, Paolo, Langerak, Anton W., Davi, Frédéric, Stamatopoulos, Kostas

“…The somatic hypermutation (SHM) status of the clonotypic immunoglobulin heavy variable (IGHV) gene is a critical biomarker for assessing the prognosis of…”
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Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL by Agathangelidis, Andreas, Chatzidimitriou, Anastasia, Gemenetzi, Katerina, Giudicelli, Veronique, Karypidou, Maria, Plevova, Karla, Davis, Zadie, Yan, Xiao-Jie, Jeromin, Sabine, Schneider, Christof, Pedersen, Lone Bredo, Tschumper, Renee C., Sutton, Lesley-Ann, Baliakas, Panagiotis, Scarfò, Lydia, van Gastel, Ellen J., Armand, Marine, Tausch, Eugen, Biderman, Bella, Baer, Constance, Bagnara, Davide, Navarro, Alba, Langlois de Septenville, Anne, Guido, Valentina, Mitterbauer-Hohendanner, Gerlinde, Dimovski, Aleksandar, Brieghel, Christian, Lawless, Sarah, Meggendorfer, Manja, Brazdilova, Kamila, Ritgen, Matthias, Facco, Monica, Tresoldi, Cristina, Visentin, Andrea, Patriarca, Andrea, Catherwood, Mark, Bonello, Lisa, Sudarikov, Andrey, Vanura, Katrina, Roumelioti, Maria, Skuhrova Francova, Hana, Moysiadis, Theodoros, Veronese, Silvio, Giannopoulos, Krzysztof, Mansouri, Larry, Karan-Djurasevic, Teodora, Sandaltzopoulos, Raphael, Bödör, Csaba, Fais, Franco, Kater, Arnon, Panovska, Irina, Rossi, Davide, Alshemmari, Salem, Panagiotidis, Panagiotis, Costeas, Paul, Espinet, Blanca, Antic, Darko, Foroni, Letizia, Montillo, Marco, Trentin, Livio, Stavroyianni, Niki, Gaidano, Gianluca, Francia di Celle, Paola, Niemann, Carsten, Campo, Elias, Anagnostopoulos, Achilles, Pott, Christiane, Fischer, Kirsten, Hallek, Michael, Oscier, David, Stilgenbauer, Stephan, Haferlach, Claudia, Jelinek, Diane, Chiorazzi, Nicholas, Pospisilova, Sarka, Lefranc, Marie-Paule, Kossida, Sofia, Langerak, Anton W., Belessi, Chrysoula, Davi, Frederic, Rosenquist, Richard, Ghia, Paolo, Stamatopoulos, Kostas

“…Chronic lymphocytic leukemia (CLL) is characterized by the existence of subsets of patients with (quasi)identical, stereotyped B-cell receptor (BcR)…”
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Plant cytosine-5 DNA methyltransferases: Structure, function, and molecular evolution by Pavlopoulou, Athanasia, Kossida, Sophia

“…A detailed analysis of the structure and function, along with evolutionary aspects, of the main plant cytosine-5 DNA methyltransferases (C5-MTases) is…”
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Updates of the ERIC recommendations on how to report the results from immunoglobulin heavy variable gene analysis in chronic lymphocytic leukemia by Chatzikonstantinou, Thomas, Agathangelidis, Andreas, Chatzidimitriou, Anastasia, Tresoldi, Cristina, Davis, Zadie, Giudicelli, Véronique, Kossida, Sofia, Belessi, Chrysoula, Rosenquist, Richard, Ghia, Paolo, Langerak, Anton W., Davi, Frédéric, Stamatopoulos, Kostas

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Inferred Allelic Variants of Immunoglobulin Receptor Genes: A System for Their Evaluation, Documentation, and Naming by Ohlin, Mats, Scheepers, Cathrine, Corcoran, Martin, Lees, William D, Busse, Christian E, Bagnara, Davide, Thörnqvist, Linnea, Bürckert, Jean-Philippe, Jackson, Katherine J L, Ralph, Duncan, Schramm, Chaim A, Marthandan, Nishanth, Breden, Felix, Scott, Jamie, Matsen Iv, Frederick A, Greiff, Victor, Yaari, Gur, Kleinstein, Steven H, Christley, Scott, Sherkow, Jacob S, Kossida, Sofia, Lefranc, Marie-Paule, van Zelm, Menno C, Watson, Corey T, Collins, Andrew M

“…Immunoglobulins or antibodies are the main effector molecules of the B-cell lineage and are encoded by hundreds of variable (V), diversity (D), and joining (J)…”
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Phylogenetic analysis of the eukaryotic RNA (cytosine-5)-methyltransferases by Pavlopoulou, Athanasia, Kossida, Sophia

“…RNA (cytosine-5)-methyltransferases (RCMTs) have been characterized both in prokaryotic and eukaryotic organisms. The RCMT family, however, remains largely…”
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Structuprint: a scalable and extensible tool for two-dimensional representation of protein surfaces by Kontopoulos, Dimitrios Georgios, Vlachakis, Dimitrios, Tsiliki, Georgia, Kossida, Sofia

“…The term 'molecular cartography' encompasses a family of computational methods for two-dimensional transformation of protein structures and analysis of their…”
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A novel mutation of the hGR gene causing Chrousos syndrome by Nicolaides, Nicolas C., Geer, Eliza B., Vlachakis, Dimitrios, Roberts, Michael L., Psarra, Anna-Maria G., Moutsatsou, Paraskevi, Sertedaki, Amalia, Kossida, Sophia, Charmandari, Evangelia

“…Background Natural mutations in the human glucocorticoid receptor (hGR, NR3C1) gene cause Chrousos syndrome, a rare condition characterized by generalized,…”
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Evolutionary Scenarios of Notch Proteins by Theodosiou, Athina, Arhondakis, Stilianos, Baumann, Marc, Kossida, Sophia

“…Notch is a highly conserved family of transmembrane receptors and transcription factors that are key players in several developmental processes. In this study,…”
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Search for Potential Markers for Prostate Cancer Diagnosis, Prognosis and Treatment in Clinical Tissue Specimens Using Amine-Specific Isobaric Tagging (iTRAQ) with Two-Dimensional Liquid Chromatography and Tandem Mass Spectrometry by Garbis, Spiros D, Tyritzis, Stavros I, Roumeliotis, Theodoros, Zerefos, Panagiotis, Giannopoulou, Eugenia G, Vlahou, Antonia, Kossida, Sophia, Diaz, Jose, Vourekas, Stavros, Tamvakopoulos, Constantin, Pavlakis, Kitty, Sanoudou, Despina, Constantinides, Constantinos A

“…This study aimed to identify candidate new diagnosis and prognosis markers and medicinal targets of prostate cancer (PCa), using state of the art proteomics. A…”
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Everolimus suppresses cancellous bone loss, bone resorption, and cathepsin K expression by osteoclasts by Kneissel, Michaela, Luong-Nguyen, Ngoc-Hong, Baptist, Myma, Cortesi, Reto, Zumstein-Mecker, Sabine, Kossida, Sophia, O'Reilly, Terry, Lane, Heidi, Susa, Mira

“…The proliferation inhibitor of the macrolide class, everolimus, is a drug shown to be effective in the prevention of organ transplant rejection and to have a…”
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DrugOn: a fully integrated pharmacophore modeling and structure optimization toolkit by Vlachakis, Dimitrios, Fakourelis, Paraskevas, Megalooikonomou, Vasileios, Makris, Christos, Kossida, Sophia

“…During the past few years, pharmacophore modeling has become one of the key components in computer-aided drug design and in modern drug discovery. DrugOn is a…”
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The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase by Roussigne, Myriam, Kossida, Sophia, Lavigne, Anne-Claire, Clouaire, Thomas, Ecochard, Vincent, Glories, Alexandra, Amalric, François, Girard, Jean-Philippe

“…We have identified a novel evolutionarily conserved protein motif – designated the THAP domain – that defines a new family of cellular factors. We have found…”
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An enhanced Markov clustering method for detecting protein complexes by Moschopoulos, C.N., Pavlopoulos, G.A., Likothanassis, S.D., Kossida, S.

“…With the recent high-throughput methods, large datasets of experimentally detected pairwise protein-protein interactions are generated. However, these data…”
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