Search Results - "Kosman, David"

Characterization of the Drosophila segment determination morphome by Surkova, Svetlana, Kosman, David, Kozlov, Konstantin, Manu, Myasnikova, Ekaterina, Samsonova, Anastasia A., Spirov, Alexander, Vanario-Alonso, Carlos E., Samsonova, Maria, Reinitz, John

“…Here we characterize the expression of the full system of genes which control the segmentation morphogenetic field of Drosophila at the protein level in one…”
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Dynamic control of positional information in the early Drosophila embryo by Reinitz, John, Jaeger, Johannes, Surkova, Svetlana, Blagov, Maxim, Janssens, Hilde, Kosman, David, Kozlov, Konstantin N, Manu, Myasnikova, Ekaterina, Vanario-Alonso, Carlos E, Samsonova, Maria, Sharp, David H

“…Morphogen gradients contribute to pattern formation by determining positional information in morphogenetic fields. Interpretation of positional information is…”
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Dynamical Analysis of Regulatory Interactions in the Gap Gene System of Drosophila melanogaster by Jaeger, Johannes, Blagov, Maxim, Kosman, David, Kozlov, Konstantin N, Manu, Myasnikova, Ekaterina, Surkova, Svetlana, Vanario-Alonso, Carlos E, Samsonova, Maria, Sharp, David H, Reinitz, John

“…Genetic studies have revealed that segment determination in Drosophila melanogaster is based on hierarchical regulatory interactions among maternal coordinate…”
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Rapid preparation of a panel of polyclonal antibodies to Drosophila segmentation proteins by Kosman, D, Small, S, Reinitz, J

“…We describe a method for rapidly raising a panel of high quality polyclonal antibodies from bacterially expressed proteins. Approximately 1(2)/3 days of…”
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Thoracic Patterning by the Drosophila Gap Gene hunchback by Wu, Xuelin, Vasisht, Vikram, Kosman, David, Reinitz, John, Small, Stephen

“…Localized gene expression patterns are critical for establishing body plans in all multicellular animals. In Drosophila, the gap gene hunchback (hb) is…”
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Concentration-dependent patterning by an ectopic expression domain of the Drosophila gap gene knirps by Kosman, D, Small, S

“…The asymmetric distribution of the gap gene knirps (kni) in discrete expression domains is critical for striped patterns of pair-rule gene expression in the…”
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Gene length may contribute to graded transcriptional responses in the Drosophila embryo by McHale, Peter, Mizutani, Claudia M., Kosman, David, MacKay, Danielle L., Belu, Mirela, Hermann, Anita, McGinnis, William, Bier, Ethan, Hwa, Terence

“…An important question in developmental biology is how relatively shallow gradients of morphogens can reliably establish a series of distinct transcriptional…”
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Analysis of pattern precision shows that Drosophila segmentation develops substantial independence from gradients of maternal gene products by Holloway, David M., Harrison, Lionel G., Kosman, David, Vanario‐Alonso, Carlos E., Spirov, Alexander V.

“…We analyze the relation between maternal gradients and segmentation in Drosophila, by quantifying spatial precision in protein patterns. Segmentation is first…”
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Computational Identification of Ftz/Ftz-F1 downstream target genes by Bowler, Timothy, Kosman, David, Licht, Jonathan D., Pick, Leslie

“…Hox genes encode DNA binding transcription factors that regulate the body plans of metazoans by regulating the expression of downstream target ‘realizator…”
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Removal of background signal from in situ data on the expression of segmentation genes in Drosophila by Myasnikova, Ekaterina, Samsonova, Maria, Kosman, David, Reinitz, John

“…Here we present a method for the removal of nonspecific background signal from fluorescently localized expression patterns of Drosophila segmentation genes…”
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Dynamical analysis of regulatory interactions in the gap gene system of Dosophila melanogaster by Jaeger, Johannes, Blagov, Maxim, Kosman, David, Kozlov, Konstantin N

“…Genetic studies have revealed that segment determination in Drosophila melanogaster is based on hierarchical regulatory interactions among maternal coordinate…”
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The dorsal morphogen gradient regulates the mesoderm determinant twist in early Drosophila embryos by JIN JIANG, KOSMAN, D, IP, Y. T, LEVINE, M

“…A gradient of the maternal morphogen dorsal (dl) initiates the differentiation of various tissues along the dorsal-ventral axis of early Drosophila embryos. dl…”
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The dorsal gradient morphogen regulates stripes of rhomboid expression in the presumptive neuroectoderm of the Drosophila embryo by IP, Y. T, PARK, R. E, KOSMAN, D, BIER, E, LEVINE, M

“…rhomboid (rho) encodes a putative transmembrane receptor that is required for the differentiation of the ventral epidermis. It is initially expressed before…”
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Establishment of the Mesoderm-Neuroectoderm Boundary in the Drosophila Embryo by Kosman, David, Ip, Y. Tony, Levine, Michael, Arora, Kavita

“…A gradient of the maternal morphogen dorsal establishes asymmetric patterns of gene expression along the dorsal-ventral axis of early embryos and activates the…”
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dorsal-twist interactions establish snail expression in the presumptive mesoderm of the Drosophila embryo by TONY IP, Y, PARK, R. E, KOSMAN, D, YAZDANBAKHSH, K, LEVINE, M

“…The first step in the differentiation of the Drosophila mesoderm is the activation of two regulatory genes, twist (twi) and snail (sna), in ventral regions of…”
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SEGMENTATION OF NUCLEI IN CONFOCAL IMAGE STACKS USING PERFORMANCE BASED THRESHOLDING by Beaver, W., Kosman, D., Tedeschi, G., Bier, E., McGinnis, W., Freund, Y.

“…Combinatorial transcriptional fluorescent in situ hybridization (CT-FLSH) is a confocal fluorescence imaging technique enabling the detection of multiple…”
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Dynamic control of positional information in the early Drosophila embryo by JAEGER, Johannes, SURKOVA, Svetlana, SHARP, David H, REINITZ, John, BLAGOV, Maxim, JANSSENS, Hilde, KOSMAN, David, KOZLOV, Konstantin N, MANU, MYASNIKOVA, Ekaterina, VANARIO-ALONSO, Carlos E, SAMSONOVA, Maria

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Stripe forming architecture of the gap gene system by Reinitz, John, Kosman, David, Vanario-Alonso, Carlos E., Sharp, David H.

“…In this report, we show that gap genes encode exactly one set of pair‐rule stripes, which occur in the native even‐skipped position. The core of this work is a…”
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