Search Results - "Koskinas, John"
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Immune System and Hepatocellular Carcinoma (HCC): New Insights into HCC Progression
Published in International journal of molecular sciences (01-07-2023)“…According to the WHO's recently released worldwide cancer data for 2020, liver cancer ranks sixth in morbidity and third in mortality among all malignancies…”
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Extrahepatic immune related manifestations in chronic hepatitis C virus infection
Published in World journal of gastroenterology : WJG (21-09-2014)“…The association of chronic hepatitis C with immune related syndromes has been frequently reported.There is a great range of clinical manifestations affecting…”
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Differential Expression of the Host Lipid Regulators ANGPTL-3 and ANGPTL-4 in HCV Infection and Treatment
Published in International journal of molecular sciences (01-08-2021)“…Host lipid metabolism reprogramming is essential for hepatitis C virus (HCV) infection and progression to severe liver disease. Direct-acting antivirals (DAAs)…”
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4
Bone disease in patients with cirrhosis of different etiology and severity; are Klotho protein and osteoprotegerin potential biomarkers?
Published in Scandinavian journal of gastroenterology (01-02-2023)“…Cirrhosis is associated with increased risk for osteoporosis and osteopenia. This study aims to further investigate this relationship by examining if etiology…”
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2021 Thalassaemia International Federation Guidelines for the Management of Transfusion‐dependent Thalassemia
Published in HemaSphere (01-08-2022)“…Beta‐thalassemia and particularly its transfusion‐dependent form (TDT) is a demanding clinical condition, requiring life‐long care and follow‐up, ideally in…”
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Intrahepatic levels and replicative activity of covalently closed circular hepatitis B virus DNA in chronically infected patients
Published in Hepatology (Baltimore, Md.) (01-09-2006)“…Hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) is responsible for viral persistence in the natural course of chronic HBV infection and during…”
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Increased Arterial Stiffness and Impaired Endothelial Function in Nonalcoholic Fatty Liver Disease: A Pilot Study
Published in American journal of hypertension (01-11-2010)“…Background Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease both in the general and pediatric population and has been associated with…”
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Cellular, Molecular and Proteomic Characteristics of Early Hepatocellular Carcinoma
Published in Current issues in molecular biology (01-10-2022)“…Hepatocellular carcinoma (HCC) accounts for the majority of primary liver cancers. Early detection/diagnosis is vital for the prognosis of HCC, whereas…”
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Speed of sound index for liver steatosis estimation: a reliability study in normal subjects
Published in Diagnostic and interventional radiology (Ankara, Turkey) (01-09-2022)“…PURPOSE Non-alcoholic fatty liver disease (NAFLD) is the most widespread type of chronic liver disease in the Western countries. Ultrasound (US) is widely used…”
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Liver innervation and hepatic function: new insights
Published in The Journal of surgical research (01-04-2015)“…Abstract The hepatic nervous system has a well-known impact on the regulation of liver function and organism homeostasis. The aim of this review is to…”
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The Epigenetic Controller Lysine-Specific Demethylase 1 (LSD1) Regulates the Outcome of Hepatitis C Viral Infection
Published in Cells (Basel, Switzerland) (01-11-2023)“…Hepatitis C virus (HCV) alters gene expression epigenetically to rearrange the cellular microenvironment in a beneficial way for its life cycle. The host…”
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Liver histology in ICU patients dying from sepsis:A clinico-pathological study
Published in World journal of gastroenterology : WJG (07-03-2008)“…AIM:To determine end-stage pathologic changes in the liver of septic patients dying in the intensive care unit. METHODS: Needle liver biopsies obtained…”
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13
Alterations in the iron homeostasis network: A driving force for macrophage-mediated hepatitis C virus persistency
Published in Virulence (17-08-2016)“…Mechanisms that favor Hepatitis C virus (HCV) persistence over clearance are unclear, but involve defective innate immunity. Chronic infection is characterized…”
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Keratin 19 protein expression is an independent predictor of survival in human hepatocellular carcinoma
Published in European journal of gastroenterology & hepatology (01-09-2015)“…AIMWe aimed to assess the clinicopathological relevance and prognostic significance of expression of the hepatic progenitor cell markers keratin 19 (K19),…”
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HCV-Induced Immunometabolic Crosstalk in a Triple-Cell Co-Culture Model Capable of Simulating Systemic Iron Homeostasis
Published in Cells (Basel, Switzerland) (30-08-2021)“…Iron is crucial to the regulation of the host innate immune system and the outcome of many infections. Hepatitis C virus (HCV), one of the major viral human…”
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E2F-1 is overexpressed and pro-apoptotic in human hepatocellular carcinoma
Published in Virchows Archiv : an international journal of pathology (01-05-2012)“…E2F-1 is a transcription factor involved in DNA synthesis and repair, cell proliferation, and apoptosis. Hyposphorylated pRb represses E2F-1 action in early G1…”
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Characteristics and prognosis of hepatocellular carcinoma in multi-transfused patients with thalassemia major. Experience of a single tertiary center
Published in Mediterranean journal of hematology and infectious diseases (26-02-2020)“…Background: In this retrospective study, records of patients with thalassemia major (TM) diagnosed with hepatocellular carcinoma (HCC) from 2008‐2018 were…”
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Emerging Role of l-Dopa Decarboxylase in Flaviviridae Virus Infections
Published in Cells (Basel, Switzerland) (05-08-2019)“…l-dopa decarboxylase (DDC) that catalyzes the biosynthesis of bioactive amines, such as dopamine and serotonin, is expressed in the nervous system and…”
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Concerns Regarding the Management of β-Thalassaemia Patients in the Era of COVID-19
Published in European medical journal. Hematology (30-07-2020)“…Many cases of pneumonia clustered in the city of Wuhan, China, were reported in December 2019, and source tracing has showed Huanan Seafood Market, Wuhan,…”
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Hepatitis C Virus (HCV)-Related Cryoglobulinemia: Cryoglobulin Type and Anti-HCV Profile
Published in Clinical and Vaccine Immunology (01-05-2013)“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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