Search Results - "Kosinski, Christoph"

Do normal D-dimer levels reliably exclude cerebral sinus thrombosis? by KOSINSKI, Christoph M, MULL, Michael, SCHWARZ, Michael, KOCH, Benno, BINIEK, Rolf, SCHLÄFER, Joachim, MILKEREIT, Eva, WILLMES, Klaus, SCHIEFER, Johannes

“…Cerebral sinus thrombosis (CST) needs to be considered in the differential diagnosis of all patients with acute headache. Early diagnosis is essential because…”
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Neural Cell Adhesion Molecule L1-Transfected Embryonic Stem Cells Promote Functional Recovery after Excitotoxic Lesion of the Mouse Striatum by Bernreuther, Christian, Dihne, Marcel, Johann, Verena, Schiefer, Johannes, Cui, Yifang, Hargus, Gunnar, Schmid, Janinne Sylvie, Xu, Jinchong, Kosinski, Christoph M, Schachner, Melitta

“…We have generated a murine embryonic stem cell line constitutively expressing L1 at all stages of neural differentiation to investigate the effects of L1…”
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Myopathy as a first symptom of Huntington's disease in a Marathon runner by Kosinski, Christoph M., Schlangen, Christiane, Gellerich, Frank N., Gizatullina, Zemfira, Deschauer, Markus, Schiefer, Johannes, Young, Anne B., Landwehrmeyer, Georg Bernhard, Toyka, Klaus V., Sellhaus, Bernd, Lindenberg, Katrin S.

“…A semi professional marathon runner at risk for Huntington's disease (HD) (43 CAG repeats) developed signs of a slowly progressive myopathy with…”
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High-capacity adenoviral vector-mediated reduction of huntingtin aggregate load in vitro and in vivo by Huang, Bin, Schiefer, Johannes, Sass, Christian, Landwehrmeyer, G Bernhard, Kosinski, Christoph M, Kochanek, Stefan

“…Huntington's disease (HD) is an autosomal dominant neurodegenerative disease caused by the expansion of a CAG trinucleotide repeat in exon 1 of the huntingtin…”
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The metabotropic glutamate receptor 5 antagonist MPEP and the mGluR2 agonist LY379268 modify disease progression in a transgenic mouse model of Huntington's disease by Schiefer, Johannes, Sprünken, Arne, Puls, Christiane, Lüesse, Hans-Gerd, Milkereit, Anna, Milkereit, Eva, Johann, Verena, Kosinski, Christoph M

“…Chronic glutamate mediated excitotoxicity has been suggested to contribute to the pathogenesis of Huntington's disease (HD). Both, inhibition of glutamate…”
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Altered Brain Neurotransmitter Receptors in Transgenic Mice Expressing a Portion of an Abnormal Human Huntington Disease Gene by Cha, Jang-Ho J., Kosinski, Christoph M., Kerner, Julie A., Alsdorf, Stephen A., Mangiarini, Laura, Davies, Stephen W., Penney, John B., Bates, Gillian P., Young, Anne B.

“…Loss of neurotransmitter receptors, especially glutamate and dopamine receptors, is one of the pathologic hallmarks of brains of patients with Huntington…”
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Low stability of huntington muscle Mitochondria against Ca2+ in R6/2 mice by Gizatullina, Zemfira Z., Lindenberg, Katrin S., Harjes, Phoebe, Chen, Ying, Kosinski, Christoph M., Landwehrmeyer, Bernhard G., Ludolph, Albert C., Striggow, Frank, Zierz, Stephan, Gellerich, Frank N.

“…Objective The aim of the present work was the detection of Mitochondrial dysfunction of Huntington's disease (HD). Methods We investigated muscle and muscle…”
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Time of transplantation and cell preparation determine neural stem cell survival in a mouse model of Huntington's disease by JOHANN, Verena, SCHIEFER, Johannes, KOSINSKI, Christoph M, SASS, Christian, MEY, Jörg, BROOK, Gary, KRIITTGEN, Alexander, SCHLANGEN, Christiane, BERNREUTHER, Christian, SCHACHNER, Melitta, DIHNE, Marcel

“…Cell replacement therapies for neurodegenerative diseases, using multipotent neural stem cells (NSCs), require above all, a good survival of the graft. In this…”
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Riluzole prolongs survival time and alters nuclear inclusion formation in a transgenic mouse model of Huntington's disease by Schiefer, Johannes, Landwehrmeyer, G. Bernhard, Lüesse, Hans-Gerd, Sprünken, Arne, Puls, Christiane, Milkereit, Anna, Milkereit, Eva, Kosinski, Christoph M.

“…Glutamate excitotoxicity has been suggested to contribute to the pathogenesis of Huntington's disease (HD). Riluzole is a substance with glutamate antagonistic…”
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Transdermal dopaminergic stimulation with rotigotine in Parkinsonian akinetic crisis by Dafotakis, Manuel, Sparing, Roland, Juzek, Agnes, Block, Frank, Kosinski, Christoph M

“…Abstract Akinetic crisis (AC) is a much-feared complication of Parkinson’s disease (PD) which may appear upon abrupt cessation or malabsorption of dopaminergic…”
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Evaluation of R6/2 HD transgenic mice for therapeutic studies in Huntington's disease: behavioral testing and impact of diabetes mellitus by Lüesse, Hans-Gerd, Schiefer, Johannes, Spruenken, Arne, Puls, Christiane, Block, Frank, Kosinski, Christoph M

“…R6/2 transgenic mice express exon 1 of the human Huntington's disease (HD) gene with an increased CAG repeat length. They develop a progressive neurological…”
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Inducing huntingtin inclusion formation in primary neuronal cell culture and in vivo by high-capacity adenoviral vectors expressing truncated and full-length huntingtin with polyglutamine expansion by Huang, Bin, Schiefer, Johannes, Sass, Christian, Kosinski, Christoph M., Kochanek, Stefan

“…Background Huntington's disease (HD) is an inherited autosomal dominant neurodegenerative disease caused by the expansion of a CAG trinucleotide repeat in exon…”
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High rate of restenosis after carotid artery stenting in patients with high-grade internal carotid artery stenosis: Medium-term follow-up by Harrer, J. U., Morschel, R., Mull, M., Kosinski, C. M.

“…Objective Carotid endarterectomy (CEA) is the goldstandard procedure for the majority of patients with high-grade symptomatic internal carotid artery stenosis…”
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Cerebral kinetics of the dopamine D2 receptor ligand [123 I]IBZM in mice by Meyer, Philipp T, Salber, Dagmar, Schiefer, Johannes, Cremer, Markus, Schaefer, Wolfgang M, Kosinski, Christoph M, Langen, Karl-Josef

“…Abstract Introduction In vivo small animal imaging of the dopaminergic system is of great interest for basic and applied neurosciences, especially in…”
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Rapid geographical clustering of wound botulism in Germany after subcutaneous and intramuscular injection of heroin by Galldiks, Norbert, Nolden-Hoverath, Silke, Kosinski, Christoph M, Stegelmeyer, Ulrike, Schmidt, Sylvia, Dohmen, Christian, Kuhn, Jens, Gerbershagen, Kathrin, Bewermeyer, Heiko, Walger, Peter, Biniek, Rolf, Neveling, Michael, Jacobs, Andreas H, Haupt, Walter F

“…Wound infections due to Clostridium botulinum in Germany are rare and occur predominantly in heroin injectors, especially after subcutaneous or intramuscular…”
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Comparison of intravenous and intraperitoneal [123 I]IBZM injection for dopamine D2 receptor imaging in mice by Meyer, Philipp T, Salber, Dagmar, Schiefer, Johannes, Cremer, Markus, Schaefer, Wolfgang M, Kosinski, Christoph M, Langen, Karl-Josef

“…Abstract Introduction Intraperitoneal (IP) injection represents an attractive alternative route of radiotracer administration for small animal imaging, e.g.,…”
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Akathisia as a side effect of antipsychotic treatment with quetiapine in a patient with Parkinson's disease by Prueter, Christian, Habermeyer, Benedikt, Norra, Christine, Kosinski, Christoph M.

“…Due to its low profile for extrapyramidal side‐effects, quetiapine has become an alternative to clozapine in the treatment of dopamimetic psychosis in patients…”
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Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease by Cha, Jang-Ho J., Frey, Ariel S., Alsdorf, Stephen A., Kerner, Julie A., Kosinski, Christoph M., Mangiarini, Laura, Penney, John B., Davies, Stephen W., Bates, Gillian P., Young, Anne B.

“…Alterations in neurotransmitter receptors are a pathological hallmark of the neurodegeneration seen in Huntington's disease (HD). However, the significance of…”
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Eyelid oedema and headache by Sparing, Roland, Kosinski, Christoph M, Krings, Timo, Schiefer, Johannes

“…A 42-year-old woman developed painless swelling of the upper eyelids (figure, A, arrows). She was seen by doctors who applied topical mydriatic drops, and…”
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Patent foramen ovale closure versus drug therapy in patients over 60 years and a follow‐up of 5 years by Eichelmann, Angelika, Kubini, Ralf, Nachoski, Dejan, Kosinski, Christoph, Becker, Michael, Aljalloud, Ali

“…Background The advantages of patent foramen ovale (PFO) closure as protection from a recurrence of stroke remains controversial compared to drug therapy,…”
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