STUDY OF SERUM E- SELECTIN LEVELS IN CARDIOVASCULAR DISORDERS IN UDUPI DISTRICT
Objective: To correlate the known pro-atherogenic risk factors like low HDL levels with E-selectin levels in angiogenesis and cardiovascular disease, and to see if E-selectin levels in blood can be used along with other parameters to screen for risk of CVDs. Methods: Serum samples of subjects betwee...
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| Published in: | Indian journal of clinical biochemistry Vol. 27; no. S1; p. S107 |
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| Main Authors: | , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Springer
24-05-2022
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| Subjects: | |
| Online Access: | Get full text |
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| Summary: | Objective: To correlate the known pro-atherogenic risk factors like low HDL levels with E-selectin levels in angiogenesis and cardiovascular disease, and to see if E-selectin levels in blood can be used along with other parameters to screen for risk of CVDs. Methods: Serum samples of subjects between the ages of 50-60 with CVD were chosen randomly on the basis of hs- Troponin- t levels and were divided into 3 groups of 15 each. The Abnova human SE- selectin immunoassaya four and a half hour solid phase ELISA was used to measure SE- selectin in serum samples. CK, CKMB- mass, hs- Troponin- t and HDL were analysed using auto analyser-Cobas 6000. Result: E-selectin showed a negative correlation with hs-Troponint in Group 2. There was a negative correlation between hs- Troponin- t, E-selectin and HDL in group 3. Conclusion: There does not appear to be any role for E-selectin as a marker in the studied population according to the present study. The fact that E- selectin has genetic polymorphism may explain the lack of significant difference in E-selectin levels. |
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| ISSN: | 0970-1915 |