Search Results - "Koshiba‐Takeuchi, Kazuko"

Combined method of whole mount and block‐face imaging: Acquisition of 3D data of gene expression pattern from conventional in situ hybridization by Sutrisno, Aldy Anindyawan, Katano, Wataru, Kawamura, Hayata, Tajika, Yuki, Koshiba‐Takeuchi, Kazuko

“…Visualization of spatiotemporal expression of a gene of interest is a fundamental technique for analyzing the involvements of genes in organ development. In…”
Get full text

Early patterning and specification of cardiac progenitors in gastrulating mesoderm by Devine, W Patrick, Wythe, Joshua D, George, Matthew, Koshiba-Takeuchi, Kazuko, Bruneau, Benoit G

“…Mammalian heart development requires precise allocation of cardiac progenitors. The existence of a multipotent progenitor for all anatomic and cellular…”
Get full text

Cardiac septation in heart development and evolution by Katano, Wataru, Moriyama, Yuuta, Takeuchi, Jun K., Koshiba‐Takeuchi, Kazuko

“…The heart is one of the vital organs and is functionalized for blood circulation from its early development. Some vertebrates have altered their living…”
Get full text

Coronary artery established through amniote evolution by Mizukami, Kaoru, Higashiyama, Hiroki, Arima, Yuichiro, Ando, Koji, Okada, Norihiro, Kose, Katsumi, Yamada, Shigehito, Takeuchi, Jun K, Koshiba-Takeuchi, Kazuko, Fukuhara, Shigetomo, Miyagawa-Tomita, Sachiko, Kurihara, Hiroki

“…Coronary arteries are a critical part of the vascular system and provide nourishment to the heart. In humans, even minor defects in coronary arteries can be…”
Get full text

Expression analysis of Baf60c during heart regeneration in axolotls and neonatal mice by Nakamura, Ryo, Koshiba‐Takeuchi, Kazuko, Tsuchiya, Megumi, Kojima, Mizuyo, Miyazawa, Asuka, Ito, Kohei, Ogawa, Hidesato, Takeuchi, Jun K.

“…Some organisms, such as zebrafish, urodele amphibians, and newborn mice, have a capacity for heart regeneration following injury. However, adult mammals fail…”
Get full text

Evolution and development of heart morphology and coronary circulation in vertebrates by Moriyama, Yuuta, Koshiba-Takeuchi, Kazuko

Get more information

Whole-Mount and Section In Situ Hybridization in Mouse Embryos for Detecting mRNA Expression and Localization by Koshiba-Takeuchi, Kazuko

“…In situ hybridization is defined as one of the most useful and powerful methods to know where genes (e.g., mRNA, ncRNA) of interest are expressed in tissues…”
Get more information

Evolution of the fish heart by sub/neofunctionalization of an elastin gene by Moriyama, Yuuta, Ito, Fumihiro, Takeda, Hiroyuki, Yano, Tohru, Okabe, Masataka, Kuraku, Shigehiro, Keeley, Fred W., Koshiba-Takeuchi, Kazuko

“…The evolution of phenotypic traits is a key process in diversification of life. However, the mechanisms underlying the emergence of such evolutionary novelties…”
Get full text

Important cardiac transcription factor genes are accompanied by bidirectional long non-coding RNAs by Hori, Yutaro, Tanimoto, Yoko, Takahashi, Satoru, Furukawa, Tetsushi, Koshiba-Takeuchi, Kazuko, Takeuchi, Jun K

“…Heart development is a relatively fragile process in which many transcription factor genes show dose-sensitive characteristics such as haploinsufficiency and…”
Get full text

Reptilian heart development and the molecular basis of cardiac chamber evolution by Latham, Stephany, Henkelman, R. Mark, Bruneau, Benoit G, Olson, Eric N, Wade, Juli, Koshiba-Takeuchi, Kazuko, Georges, Romain O, Cebra-Thomas, Judith, Gilbert, Scott F, Nemer, Mona, Kaynak, Bogac L, Beck, Laural, Black, Brian L, Sukonnik, Tatyana, Mori, Alessandro D, Takeuchi, Jun K

“…The emergence of terrestrial life witnessed the need for more sophisticated circulatory systems. This has evolved in birds, mammals and crocodilians into…”
Get full text

Transcriptional Dynamics of Immortalized Human Mesenchymal Stem Cells during Transformation by Takeuchi, Masao, Higashino, Atsunori, Takeuchi, Kikuko, Hori, Yutaro, Koshiba-Takeuchi, Kazuko, Makino, Hatsune, Monobe, Yoko, Kishida, Marina, Adachi, Jun, Takeuchi, Jun, Tomonaga, Takeshi, Umezawa, Akihiro, Kameoka, Yosuke, Akagi, Ken-Ichi

“…Comprehensive analysis of alterations in gene expression along with neoplastic transformation in human cells provides valuable information about the molecular…”
Get full text

Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart by Bruneau, Benoit G, Koshiba-Takeuchi, Kazuko, Takeuchi, Jun K, Arruda, Eric P, Kathiriya, Irfan S, Mo, Rong, Hui, Chi-chung, Srivastava, Deepak

“…Human mutations in TBX5, a gene encoding a T-box transcription factor, and SALL4, a gene encoding a zinc-finger transcription factor, cause similar upper limb…”
Get full text

Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development by Takeuchi, Jun K, Mileikovskaia, Maria, Koshiba-Takeuchi, Kazuko, Heidt, Analeah B, Mori, Alessandro D, Arruda, Eric P, Gertsenstein, Marina, Georges, Romain, Davidson, Lorinda, Mo, Rong, Hui, Chi-Chung, Henkelman, R Mark, Nemer, Mona, Black, Brian L, Nagy, Andras, Bruneau, Benoit G

“…To elucidate the function of the T-box transcription factor Tbx20 in mammalian development, we generated a graded loss-of-function series by transgenic RNA…”
Get full text

Correction: Transcriptional Dynamics of Immortalized Human Mesenchymal Stem Cells during Transformation by Takeuchi, Masao, Higashino, Atsunori, Takeuchi, Kikuko, Hori, Yutaro, Koshiba-Takeuchi, Kazuko, Makino, Hatsune, Monobe, Yoko, Kishida, Marina, Adachi, Jun, Takeuchi, Jun, Tomonaga, Takeshi, Umezawa, Akihiro, Kameoka, Yosuke, Akagi, Ken-ichi

Get full text

Tbx5 specifies the left/right ventricles and ventricular septum position during cardiogenesis by Takeuchi, Jun K, Ohgi, Makoto, Koshiba-Takeuchi, Kazuko, Shiratori, Hidetaka, Sakaki, Ichiro, Ogura, Keiko, Saijoh, Yukio, Ogura, Toshihiko

“…Extensive misexpression studies were carried out to explore the roles played by Tbx5 , the expression of which is excluded from the right ventricle (RV) during…”
Get full text

Tbx5 and Tbx4 trigger limb initiation through activation of the Wnt/Fgf signaling cascade by Takeuchi, Jun K, Koshiba-Takeuchi, Kazuko, Suzuki, Takayuki, Kamimura, Mika, Ogura, Keiko, Ogura, Toshihiko

“…A tight loop between members of the fibroblast growth factor and the Wnt families plays a key role in the initiation of vertebrate limb development. We show…”
Get full text

Tbx5 and the Retinotectum Projection by Koshiba-Takeuchi, Kazuko, Takeuchi, Jun K., Matsumoto, Ken, Momose, Tsuyoshi, Uno, Kenichiro, Hoepker, Veit, Ogura, Keiko, Takahashi, Naoki, Nakamura, Harukazu, Yasuda, Kunio, Ogura, Toshihiko

“…Dorsal and ventral aspects of the eye are distinct from the early stages of development. The developing eye cup grows dorsally, and the choroidal fissure is…”
Get full text

Diffusion of Nodal Signaling Activity in the Absence of the Feedback Inhibitor Lefty2 by Meno, Chikara, Takeuchi, Jun, Sakuma, Rui, Koshiba-Takeuchi, Kazuko, Ohishi, Sachiko, Saijoh, Yukio, Miyazaki, Jun-ichi, ten Dijke, Peter, Ogura, Toshihiko, Hamada, Hiroshi

“…The role of Lefty2 in left–right patterning was investigated by analysis of mutant mice that lack asymmetric expression of lefty2. These animals exhibited…”
Get full text

Significance of whole-genome duplications on the emergence of evolutionary novelties by Moriyama, Yuuta, Koshiba-Takeuchi, Kazuko

“…Abstract Acquisition of evolutionary novelties is a fundamental process for adapting to the external environment and invading new niches and results in the…”
Get full text

Vertebrate crossveinless 2 is secreted and acts as an extracellular modulator of the BMP signaling cascade by Kamimura, Mika, Matsumoto, Ken, Koshiba‐Takeuchi, Kazuko, Ogura, Toshihiko

“…In vertebrates and invertebrates, BMP/Dpp (Bone Morphogenetic Protein/Decapentaplegic) signaling regulates the orchestrated processes of embryogenesis. Recent…”
Get full text