Lipid composition and Na+,K+-ATPase activity in erythrocyte membranes of patients with type 2 diabetes mellitusand dyslipoproteinemia

Aim. To study lipid composition and Na+,K+-Na+,K+-ATPase activity in erythrocyte membranes of patients with type 2 diabetes mellitus and dyslipoproteinemia. Materials and methods. The study included 40 patients (22 men and 18 women) aged 40-65 years with DM2. Results. The patients had abnormal lipid...

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Published in:	Sakharnyĭ diabet Vol. 13; no. 1; pp. 41 - 44
Main Authors:	Kravets, Elena Borisovna, Stepovaya, Elena Alekseevna, Koshchevets, Tatiana Yur'evna, Medvedeva, Olesya Dmitrievna, Yakovleva, Natalya Mikhailovna, Yadmaa, Oyuunchimeg, Ananina, Elena Alexandrovna
Format:	Journal Article
Language:	English
Published:	Endocrinology Research Centre 15-03-2010
Subjects:	diabetic dyslipoproteinemia erythrocyte k+-atpase activity lipids membrane na+ type 2 diabetes mellitus
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Summary:	Aim. To study lipid composition and Na+,K+-Na+,K+-ATPase activity in erythrocyte membranes of patients with type 2 diabetes mellitus and dyslipoproteinemia. Materials and methods. The study included 40 patients (22 men and 18 women) aged 40-65 years with DM2. Results. The patients had abnormal lipid composition and impaired Na+,K+-Na+,K+-ATPase activity in erythrocyte membranes. The magnitude of thesechanges depended on the duration of pathology, severity of diabetic dyslipoproteinemia, and quality of compensation of carbohydrate metabolism. Conclusion. Aim. Investigation of lipid dysorganization in erythrocyte membranes in patients with type 2 diabetes mellitus yields data for the developmentof therapeutic modalities to correct dyslipoproteinemia.
ISSN:	2072-0351 2072-0378
DOI:	10.14341/2072-0351-6015