Search Results - "Koschmann, Jeannette"

Walking pathways with positive feedback loops reveal DNA methylation biomarkers of colorectal cancer by Kel, Alexander, Boyarskikh, Ulyana, Stegmaier, Philip, Leskov, Leonid S, Sokolov, Andrey V, Yevshin, Ivan, Mandrik, Nikita, Stelmashenko, Daria, Koschmann, Jeannette, Kel-Margoulis, Olga, Krull, Mathias, Martínez-Cardús, Anna, Moran, Sebastian, Esteller, Manel, Kolpakov, Fedor, Filipenko, Maxim, Wingender, Edgar

“…The search for molecular biomarkers of early-onset colorectal cancer (CRC) is an important but still quite challenging and unsolved task. Detection of CpG…”
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RNA isolation from precision-cut lung slices (PCLS) from different species by Niehof, Monika, Hildebrandt, Tobias, Danov, Olga, Arndt, Kirsten, Koschmann, Jeannette, Dahlmann, Franziska, Hansen, Tanja, Sewald, Katherina

“…Functional 3D organ models such as precision-cut lung slices (PCLS) have recently captured the attention of biomedical research. To enable wider implementation…”
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Substantiate a read-across hypothesis by using transcriptome data-A case study on volatile diketones by Drake, Christina, Wehr, Matthias M, Zobl, Walter, Koschmann, Jeannette, De Lucca, David, Kühne, Britta A, Hansen, Tanja, Knebel, Jan, Ritter, Detlef, Boei, Jan, Vrieling, Harry, Bitsch, Annette, Escher, Sylvia E

“…This case study explores the applicability of transcriptome data to characterize a common mechanism of action within groups of short-chain aliphatic α-, β-,…”
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Multi-omics “upstream analysis” of regulatory genomic regions helps identifying targets against methotrexate resistance of colon cancer by Kel, Alexander E., Stegmaier, Philip, Valeev, Tagir, Koschmann, Jeannette, Poroikov, Vladimir, Kel-Margoulis, Olga V., Wingender, Edgar

“…[Display omitted] •Upstream analysis strategy for multi-omics data is proposed.•Drug targets are predicted by search for TFBS and analysis of signaling…”
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Bioinformatic pipelines to predict respiratory toxicity and reduce animal testing by Koschmann, Jeannette

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"Upstream Analysis": An Integrated Promoter-Pathway Analysis Approach to Causal Interpretation of Microarray Data by Koschmann, Jeannette, Bhar, Anirban, Stegmaier, Philip, Kel, Alexander E, Wingender, Edgar

“…A strategy is presented that allows a causal analysis of co-expressed genes, which may be subject to common regulatory influences. A state-of-the-art promoter…”
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Integration of Bioinformatics and Synthetic Promoters Leads to the Discovery of Novel Elicitor-Responsive cis-Regulatory Sequences in Arabidopsis by Koschmann, Jeannette, Machens, Fabian, Becker, Marlies, Niemeyer, Julia, Schulze, Jutta, Bülow, Lorenz, Stahl, Dietmar J., Hehl, Reinhard

“…A combination of bioinformatic tools, high-throughput gene expression profiles, and the use of synthetic promoters is a powerful approach to discover and…”
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Integration of Bioinformatics and Synthetic Promoters Leads to the Discovery of Novel Elicitor-Responsive cis-Regulatory Sequences in Arabidopsis1[C][W][OA] by Koschmann, Jeannette, Machens, Fabian, Becker, Marlies, Niemeyer, Julia, Schulze, Jutta, Bülow, Lorenz, Stahl, Dietmar J., Hehl, Reinhard

“…A combination of bioinformatic tools, high-throughput gene expression profiles, and the use of synthetic promoters is a powerful approach to discover and…”
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